| Identification |
|---|
| HMDB Protein ID
| CDBP02826 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calmegin |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CLGN |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Probably plays an important role in spermatogenesis. Binds calcium ions |
| GO Classification
|
| Component |
| endoplasmic reticulum |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| unfolded protein binding |
| protein binding |
| calcium ion binding |
| Process |
| protein metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular protein metabolic process |
| protein folding |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q28.3-q31.1 |
| SNPs
| CLGN |
| Gene Sequence
|
>1833 bp
ATGCATTTCCAAGCCTTTTGGCTATGTTTGGGTCTTCTGTTCATCTCAATTAATGCAGAA
TTTATGGATGATGATGTTGAGACGGAAGACTTTGAAGAAAATTCAGAAGAAATTGATGTT
AATGAAAGTGAACTTTCCTCAGAGATTAAATATAAGACACCTCAACCTATAGGAGAAGTA
TATTTTGCAGAAACTTTTGATAGTGGAAGGTTGGCTGGATGGGTCTTATCAAAAGCAAAG
AAAGATGACATGGATGAGGAAATTTCAATATACGATGGAAGATGGGAAATTGAAGAGTTG
AAAGAAAACCAGGTACCTGGTGACAGAGGACTGGTATTAAAATCTAGAGCAAAGCATCAT
GCAATATCTGCTGTATTAGCAAAACCATTCATTTTTGCTGATAAACCCTTGATAGTTCAA
TATGAAGTAAATTTTCAAGATGGTATTGATTGTGGAGGTGCATACATTAAACTCCTAGCA
GACACCGATGATTTGATTCTGGAAAACTTTTATGATAAAACATCCTATATCATTATGTTT
GGACCAGATAAATGTGGAGAAGATTATAAACTTCATTTTATCTTCAGACATAAACATCCC
AAAACTGGAGTTTTCGAAGAGAAACATGCCAAACCTCCAGATGTAGACCTTAAAAAGTTC
TTTACAGACAGGAAGACTCATCTTTATACCCTTGTGATGAATCCAGATGACACATTTGAG
GTGTTAGTTGATCAAACAGTTGTAAACAAAGGAAGCCTCCTAGAGGATGTGGTTCCTCCT
ATCAAACCTCCCAAAGAAATTGAAGATCCCAATGATAAAAAACCTGAGGAATGGGATGAA
AGAGCAAAAATTCCTGATCCTTCTGCCGTCAAACCAGAAGACTGGGATGAAAGTGAACCT
GCCCAAATAGAAGATTCAAGTGTTGTTAAACCTGCTGGCTGGCTTGATGATGAACCAAAA
TTTATCCCTGATCCTAATGCTGAAAAACCTGATGACTGGAATGAAGACACGGATGGAGAA
TGGGAGGCACCTCAGATTCTTAATCCAGCATGTCGGATTGGGTGTGGTGAGTGGAAACCT
CCCATGATAGATAACCCAAAATACAAAGGAGTATGGAGACCTCCACTGGTCGATAATCCT
AACTATCAGGGAATCTGGAGTCCTCGAAAAATTCCTAATCCAGATTATTTCGAAGATGAT
CATCCATTTCTTCTGACTTCTTTCAGTGCTCTTGGTTTAGAGCTTTGGTCTATGACCTCT
GATATCTACTTTGATAATTTTATTATCTGTTCGGAAAAGGAAGTAGCAGATCACTGGGCT
GCAGATGGTTGGAGATGGAAAATAATGATAGCAAATGCTAATAAGCCTGGTGTATTAAAA
CAGTTAATGGCAGCTGCTGAAGGGCACCCATGGCTTTGGTTGATTTATCTTGTGACAGCA
GGAGTGCCAATAGCATTAATTACTTCATTTTGTTGGCCAAGAAAAGTAAAGAAAAAACAT
AAAGATACAGAGTATAAAAAAACCGACATATGTATACCACAAACAAAAGGAGTACTAGAG
CAAGAAGAAAAGGAAGAGAAAGCAGCCCTGGAAAAACCAATGGACCTGGAAGAGGAAAAA
AAGCAAAATGATGGTGAAATGCTTGAAAAAGAAGAGGAAAGTGAACCTGAGGAAAAGAGT
GAAGAAGAAATTGAAATCATAGAAGGGCAAGAAGAAAGTAATCAATCAAATAAGTCTGGG
TCAGAGGATGAGATGAAAGAAGCAGATGAGAGCACAGGATCTGGAGATGGGCCGATAAAG
TCAGTACGCAAAAGAAGAGTACGAAAGGACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 610 |
| Molecular Weight
| 70038.0 |
| Theoretical pI
| 4.3 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calmegin
MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV
YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH
AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF
GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE
VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP
AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP
PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS
DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA
GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK
KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK
SVRKRRVRKD
|
| External Links |
|---|
| GenBank ID Protein
| 193787446 |
| UniProtKB/Swiss-Prot ID
| O14967 |
| UniProtKB/Swiss-Prot Entry Name
| CLGN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK093096 |
| GeneCard ID
| CLGN |
| GenAtlas ID
| CLGN |
| HGNC ID
| HGNC:2060 |
| References |
|---|
| General References
| Not Available |