Showing Protein C-type lectin domain family 4 member A (CDBP02803)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02803
Secondary Accession Numbers Not Available
Name C-type lectin domain family 4 member A
Description Not Available
Synonyms
  1. C-type lectin DDB27
  2. C-type lectin superfamily member 6
  3. Dendritic cell immunoreceptor
  4. Lectin-like immunoreceptor
Gene Name CLEC4A
Protein Type Enzyme
Biological Properties
General Function Involved in sugar binding
Specific Function May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation
GO Classification
Function
binding
carbohydrate binding
sugar binding
Cellular Location
  1. Membrane
  2. Single-pass type II membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12p13
SNPs CLEC4A
Gene Sequence 
>714 bp
ATGACTTCGGAAATCACTTATGCTGAAGTGAGGTTCAAAAATGAATTCAAGTCCTCAGGC
ATCAACACAGCCTCTTCTGCAGCTTCCAAGGAGAGGACTGCCCCTCTCAAAAGTAATACC
GGATTCCCCAAGCTGCTTTGTGCCTCACTGTTGATATTTTTCCTGCTATTGGCAATCTCA
TTCTTTATTGCTTTTGTCATTTTCTTTCAAAAATATTCTCAGCTTCTTGAAAAAAAGACT
ACAAAAGAGCTGGTTCATACAACATTGGAGTGTGTGAAAAAAAATATGCCCGTGGAAGAG
ACAGCCTGGAGCTGTTGCCCAAAGAATTGGAAGTCATTTAGTTCCAACTGCTACTTTATT
TCTACTGAATCAGCATCTTGGCAAGACTGTGAGAAGGACTGTGCTAGAATGGAGGCTCAC
CTGCTGGTGATAAACACTCAAGAAGAGCAGGATTTCATCTTCCAGAATCTGCAAGAAGAA
TCTGCTTATTTTGTGGGGCTCTCAGATCCAGAAGGTCAGCGACATTGGCAATGGGTTGAT
CAGACACCATACAATGAAAGTTCCACATTCTGGCATCCACGTGAGCCCAGTGATCCCAAT
GAGCGCTGCGTTGTGCTAAATTTTCGTAAATCACCCAAAAGATGGGGCTGGAATGATGTT
AATTGTCTTGGTCCTCAAAGGTCAGTTTGTGAGATGATGAAGATCCACTTATGA
Protein Properties
Number of Residues 237
Molecular Weight 27512.0
Theoretical pI 6.76
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["49-69"]
Protein Sequence 
>C-type lectin domain family 4 member A
MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAIS
FFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFI
STESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVD
QTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL
GenBank ID Protein 8489015
UniProtKB/Swiss-Prot ID Q9UMR7
UniProtKB/Swiss-Prot Entry Name CLC4A_HUMAN
PDB IDs Not Available
GenBank Gene ID AF067800
GeneCard ID CLEC4A
GenAtlas ID CLEC4A
HGNC ID HGNC:13257
References
General References Not Available