| Identification |
|---|
| HMDB Protein ID
| CDBP02802 |
| Secondary Accession Numbers
| Not Available |
| Name
| C-type lectin domain family 10 member A |
| Description
| Not Available |
| Synonyms
|
- C-type lectin superfamily member 14
- CD301 antigen
- Macrophage lectin 2
|
| Gene Name
| CLEC10A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sugar binding |
| Specific Function
| Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| binding |
| carbohydrate binding |
| sugar binding |
|
| Cellular Location
|
- Membrane
- Single-pass type II membrane protein (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p13.1 |
| SNPs
| CLEC10A |
| Gene Sequence
|
>951 bp
ATGACAAGGACGTATGAAAACTTCCAGTACTTGGAGAATAAGGTGAAAGTCCAGGGGTTT
AAAAATGGGCCACTTCCTCTCCAGTCCCTCCTGCAGCGTCTCTGCTCTGGGCCCTGCCAT
CTCCTGCTGTCCCTGGGCCTCGGCCTCCTGCTGCTGGTCATCATCTGTGTGGTTGGATTC
CAAAATTCCAAATTTCAGAGGGACCTGGTGACCCTGAGAACAGATTTTAGCAACTTCACC
TCAAACACTGTGGCGGAGATCCAGGCACTGACTTCCCAGGGCAGCAGCTTGGAAGAAACG
ATAGCATCTCTGAAAGCTGAGGTGGAGGGTTTCAAGCAGGAACGGCAGGCAGGGGTATCT
GAGCTCCAGGAACACACTACGCAGAAGGCACACCTAGGCCACTGTCCCCACTGCCCATCT
GTGTGTGTCCCAGTTCATTCTGAAATGCTCCTGCGAGTCCAGCAGCTGGTGCAAGACCTG
AAGAAACTGACCTGCCAGGTGGCTACTCTCAACAACAATGCCTCCACTGAAGGGACCTGC
TGCCCTGTCAACTGGGTGGAGCACCAAGACAGCTGCTACTGGTTCTCTCACTCTGGGATG
TCCTGGGCCGAGGCTGAGAAGTACTGCCAGCTGAAGAACGCCCACCTGGTGGTCATCAAC
TCCAGGGAGGAGCAGAATTTTGTCCAGAAATATCTAGGCTCCGCATACACCTGGATGGGC
CTCAGTGACCCTGAAGGAGCCTGGAAGTGGGTGGATGGAACAGACTATGCGACCGGCTTC
CAGAACTGGAAGCCAGGCCAGCCAGACGACTGGCAGGGGCACGGGCTGGGTGGAGGCGAG
GACTGTGCTCACTTCCATCCAGACGGCAGGTGGAATGACGACGTCTGCCAGAGGCCCTAC
CACTGGGTCTGCGAGGCTGGCCTGGGTCAGACCAGCCAGGAGAGTCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 316 |
| Molecular Weight
| 35445.7 |
| Theoretical pI
| 5.99 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>C-type lectin domain family 10 member A
MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGF
QNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVS
ELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTC
CPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMG
LSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPY
HWVCEAGLGQTSQESH
|
| External Links |
|---|
| GenBank ID Protein
| 33667103 |
| UniProtKB/Swiss-Prot ID
| Q8IUN9 |
| UniProtKB/Swiss-Prot Entry Name
| CLC10_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_182906.2 |
| GeneCard ID
| CLEC10A |
| GenAtlas ID
| CLEC10A |
| HGNC ID
| HGNC:16916 |
| References |
|---|
| General References
| Not Available |