| Identification |
|---|
| HMDB Protein ID
| CDBP02795 |
| Secondary Accession Numbers
| Not Available |
| Name
| C-C chemokine receptor type 9 |
| Description
| Not Available |
| Synonyms
|
- C-C CKR-9
- CC-CKR-9
- CCR-9
- CDw199 antigen
- G-protein coupled receptor 28
- GPR-9-6
|
| Gene Name
| CCR9 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection |
| GO Classification
|
| Component |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| c-c chemokine receptor activity |
| molecular transducer activity |
| signal transducer activity |
| peptide receptor activity |
| peptide receptor activity, g-protein coupled |
| receptor activity |
| g-protein chemoattractant receptor activity |
| chemokine receptor activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p21.3 |
| SNPs
| CCR9 |
| Gene Sequence
|
>1110 bp
ATGACACCCACAGACTTCACAAGCCCTATTCCTAACATGGCTGATGACTATGGCTCTGAA
TCCACATCTTCCATGGAAGACTACGTTAACTTCAACTTCACTGACTTCTACTGTGAGAAA
AACAATGTCAGGCAGTTTGCGAGCCATTTCCTCCCACCCTTGTACTGGCTCGTGTTCATC
GTGGGTGCCTTGGGCAACAGTCTTGTTATCCTTGTCTACTGGTACTGCACAAGAGTGAAG
ACCATGACCGACATGTTCCTTTTGAATTTGGCAATTGCTGACCTCCTCTTTCTTGTCACT
CTTCCCTTCTGGGCCATTGCTGCTGCTGACCAGTGGAAGTTCCAGACCTTCATGTGCAAG
GTGGTCAACAGCATGTACAAGATGAACTTCTACAGCTGTGTGTTGCTGATCATGTGCATC
AGCGTGGACAGGTACATTGCCATTGCCCAGGCCATGAGAGCACATACTTGGAGGGAGAAA
AGGCTTTTGTACAGCAAAATGGTTTGCTTTACCATCTGGGTATTGGCAGCTGCTCTCTGC
ATCCCAGAAATCTTATACAGCCAAATCAAGGAGGAATCCGGCATTGCTATCTGCACCATG
GTTTACCCTAGCGATGAGAGCACCAAACTGAAGTCAGCTGTCTTGACCCTGAAGGTCATT
CTGGGGTTCTTCCTTCCCTTCGTGGTCATGGCTTGCTGCTATACCATCATCATTCACACC
CTGATACAAGCCAAGAAGTCTTCCAAGCACAAAGCCCTAAAAGTGACCATCACTGTCCTG
ACCGTCTTTGTCTTGTCTCAGTTTCCCTACAACTGCATTTTGTTGGTGCAGACCATTGAC
GCCTATGCCATGTTCATCTCCAACTGTGCCGTTTCCACCAACATTGACATCTGCTTCCAG
GTCACCCAGACCATCGCCTTCTTCCACAGTTGCCTGAACCCTGTTCTCTATGTTTTTGTG
GGTGAGAGATTCCGCCGGGATCTCGTGAAAACCCTGAAGAACTTGGGTTGCATCAGCCAG
GCCCAGTGGGTTTCATTTACAAGGAGAGAGGGAAGCTTGAAGCTGTCGTCTATGTTGCTG
GAGACAACCTCAGGAGCACTCTCCCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 369 |
| Molecular Weight
| 42015.3 |
| Theoretical pI
| 8.26 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["54-74", "86-106", "128-148", "167-187", "219-239", "255-275", "301-321"]
|
| Protein Sequence
|
>C-C chemokine receptor type 9
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
ETTSGALSL
|
| External Links |
|---|
| GenBank ID Protein
| 4886432 |
| UniProtKB/Swiss-Prot ID
| P51686 |
| UniProtKB/Swiss-Prot Entry Name
| CCR9_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ132337 |
| GeneCard ID
| CCR9 |
| GenAtlas ID
| CCR9 |
| HGNC ID
| HGNC:1610 |
| References |
|---|
| General References
| Not Available |