| Identification |
| HMDB Protein ID
| CDBP02787 |
| Secondary Accession Numbers
| Not Available |
| Name
| C-C motif chemokine 28 |
| Description
| Not Available |
| Synonyms
|
- MEC
- Mucosae-associated epithelial chemokine
- Protein CCK1
- Small-inducible cytokine A28
|
| Gene Name
| CCL28 |
| Protein Type
| Receptor |
| Biological Properties |
| General Function
| Involved in chemokine activity |
| Specific Function
| Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner |
| GO Classification
|
| Component |
| extracellular region |
| Function |
| cytokine activity |
| chemokine activity |
| binding |
| protein binding |
| receptor binding |
| Process |
| immune system process |
| immune response |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:5 |
| Locus
| 5p12 |
| SNPs
| CCL28 |
| Gene Sequence
|
>384 bp
ATGCAGCAGAGAGGACTCGCCATCGTGGCCTTGGCTGTCTGTGCGGCCCTACATGCCTCA
GAAGCCATACTTCCCATTGCCTCCAGCTGTTGCACGGAGGTTTCACATCATATTTCCAGA
AGGCTCCTGGAAAGAGTGAATATGTGTCGCATCCAGAGAGCTGATGGGGATTGTGACTTG
GCTGCTGTCATCCTTCATGTCAAGCGCAGAAGAATCTGTGTCAGCCCGCACAACCATACT
GTTAAGCAGTGGATGAAAGTGCAAGCTGCCAAGAAAAATGGTAAAGGAAATGTTTGCCAC
AGGAAGAAACACCATGGCAAGAGGAACAGTAACAGGGCACATCAGGGGAAACACGAAACA
TACGGCCATAAAACTCCTTATTAG
|
| Protein Properties |
| Number of Residues
| 127 |
| Molecular Weight
| 14279.5 |
| Theoretical pI
| 10.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>C-C motif chemokine 28
MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL
AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET
YGHKTPY
|
| External Links |
| GenBank ID Protein
| 12002127 |
| UniProtKB/Swiss-Prot ID
| Q9NRJ3 |
| UniProtKB/Swiss-Prot Entry Name
| CCL28_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF110384 |
| GeneCard ID
| CCL28 |
| GenAtlas ID
| CCL28 |
| HGNC ID
| HGNC:17700 |
| References |
| General References
| Not Available |