| Identification |
|---|
| HMDB Protein ID
| CDBP02784 |
| Secondary Accession Numbers
| Not Available |
| Name
| Voltage-dependent calcium channel gamma-like subunit |
| Description
| Not Available |
| Synonyms
|
- Neuronal voltage-gated calcium channel gamma-like subunit
- Transmembrane protein 37
|
| Gene Name
| TMEM37 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium channel activity |
| Specific Function
| Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2q14.2 |
| SNPs
| TMEM37 |
| Gene Sequence
|
>573 bp
ATGACTGCCGTCGGCGTGCAGGCCCAGAGGCCTTTGGGCCAAAGGCAGCCCCGCCGGTCC
TTCTTTGAATCCTTCATCCGGACCCTCATCATCACGTGTGTGGCCCTGGCTGTGGTCCTG
TCCTCGGTCTCCATTTGTGATGGGCACTGGCTCCTGGCTGAGGACCGCCTCTTCGGGCTC
TGGCACTTCTGCACCACCACCAACCAGACGATCTGCTTCAGAGACCTGGGCCAGGCCCAT
GTGCCCGGGCTGGCCGTGGGCATGGGCCTGGTACGCAGCGTGGGCGCCTTGGCCGTGGTG
GCCGCCATTTTTGGCCTGGAGTTCCTCATGGTGTCCCAGTTGTGCGAGGACAAACACTCA
CAGTGCAAGTGGGTCATGGGTTCCATCCTCCTCCTGGTGTCTTTCGTCCTCTCCTCCGGC
GGGCTCCTGGGTTTTGTGATCCTCCTCAGGAACCAAGTCACACTCATCGGCTTCACCCTA
ATGTTTTGGTGCGAATTCACTGCCTCCTTCCTCCTCTTCCTGAACGCCATCAGCGGCCTT
CACATCAACAGCATCACCCATCCCTGGGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 190 |
| Molecular Weight
| 20931.6 |
| Theoretical pI
| 7.79 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- ["25-45", "96-116", "131-151", "155-175"]
|
| Protein Sequence
|
>Voltage-dependent calcium channel gamma-like subunit
MTAVGVQAQRPLGQRQPRRSFFESFIRTLIITCVALAVVLSSVSICDGHWLLAEDRLFGL
WHFCTTTNQTICFRDLGQAHVPGLAVGMGLVRSVGALAVVAAIFGLEFLMVSQLCEDKHS
QCKWVMGSILLLVSFVLSSGGLLGFVILLRNQVTLIGFTLMFWCEFTASFLLFLNAISGL
HINSITHPWE
|
| External Links |
|---|
| GenBank ID Protein
| 116325983 |
| UniProtKB/Swiss-Prot ID
| Q8WXS4 |
| UniProtKB/Swiss-Prot Entry Name
| CCGL_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_183240.2 |
| GeneCard ID
| TMEM37 |
| GenAtlas ID
| TMEM37 |
| HGNC ID
| HGNC:18216 |
| References |
|---|
| General References
| Not Available |