| Identification |
|---|
| HMDB Protein ID
| CDBP02783 |
| Secondary Accession Numbers
| Not Available |
| Name
| Voltage-dependent calcium channel gamma-8 subunit |
| Description
| Not Available |
| Synonyms
|
- Neuronal voltage-gated calcium channel gamma-8 subunit
|
| Gene Name
| CACNG8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion transport |
| Specific Function
| Thought to stabilize the calcium channel in an inactivated (closed) state |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Process |
| di-, tri-valent inorganic cation transport |
| divalent metal ion transport |
| calcium ion transport |
| establishment of localization |
| transport |
| ion transport |
| cation transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.4 |
| SNPs
| CACNG8 |
| Gene Sequence
|
>1278 bp
CTGGAGTCGCTGAAGCGCTGGAACGAAGAGCGGGGCCTCTGGTGCGAGAAGGGGGTGCAG
GTGCTGCTGACGACGGTGGGCGCCTTCGCCGCCTTCGGCCTCATGACCATCGCCATCAGC
ACTGACTACTGGCTCTACACGCGCGCCCTCATCTGCAACACCACCAACCTCACGGCCGGC
GGCGACGACGGGACCCCCCACCGCGGGGGCGGCGGCGCCTCGGAGAAGAAGGACCCCGGC
GGCCTCACGCACTCGGGCCTCTGGAGGATCTGCTGCCTGGAAGGGTTGAAAAGAGGCGTC
TGCGTGAAGATCAATCATTTCCCGGAGGACACGGACTACGACCACGACAGCGCGGAGTAT
CTACTCCGAGTTGTCCGGGCCTCCAGCATCTTCCCCATCCTTAGCGCCATCCTGCTGCTG
CTCGGGGGTGTGTGCGTGGCGGCCTCCCGCGTCTACAAGTCCAAGAGGAACATCATTCTG
GGCGCAGGGATCCTGTTCGTGGCAGCAGGCCTGAGCAACATCATCGGCGTGATCGTGTAC
ATCTCCGCCAACGCGGGCGAGCCGGGCCCGAAGCGGGACGAGGAGAAGAAAAACCACTAC
TCGTACGGCTGGTCCTTCTACTTCGGCGGGCTGTCGTTCATCCTGGCCGAGGTGATAGGC
GTGCTGGCCGTCAACATCTACATCGAGCGCAGCCGCGAGGCGCACTGCCAGTCTCGCTCG
GACCTGCTCAAGGCCGGCGGGGGCGCGGGCGGCAGTGGCGGGAGCGGCCCCTCGGCCATC
CTCCGTCTGCCCAGTTACCGCTTCCGCTACCGCCGCCGCTCCCGCTCTAGCTCCCGCTCC
AGCGAGCCGTCGCCGTCGCGGGACGCGTCTCCCGGCGGCCCCGGGGGCCCGGGCTTTGCC
TCCACGGACATCTCCATGTACACGCTCAGCCGCGACCCCTCCAAGGGCAGCGTGGCCGCG
GGGCTGGCGGGGGCCGGCGGCGGCGGCGGCGGCGCCGTGGGGGCGTTCGGCGGCGCGGCC
GGGGGCGCCGGGGGCGGCGGCGGAGGCGGCGGCGGGGCGGGTGCCGAGCGGGACCGCGGG
GGGGCGTCCGGCTTCCTCACGCTGCACAACGCCTTCCCCAAGGAGGCGGGCGGCGGCGTC
ACGGTCACGGTCACCGGGCCGCCCGCCCCGCCCGCGCCCGCGCCACCCGCGCCCTCTGCG
CCCGCCCCCGGGACCCTGGCCAAGGAGGCCGCCGCCTCCAACACCAACACGCTCAACAGG
AAAACCACGCCTGTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 425 |
| Molecular Weight
| 43480.7 |
| Theoretical pI
| 9.85 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["19-39", "129-149", "158-178", "208-228", "318-338"]
|
| Protein Sequence
|
>Voltage-dependent calcium channel gamma-8 subunit
MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG
GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY
LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY
ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS
DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA
STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG
GSSGFLTLHNAFPKEAGGGVTVTVTRPPAPPAPRHPAPSAPAPGTLAKGAAASNTNTLNR
KTTPV
|
| External Links |
|---|
| GenBank ID Protein
| 24586686 |
| UniProtKB/Swiss-Prot ID
| Q8WXS5 |
| UniProtKB/Swiss-Prot Entry Name
| CCG8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_031895.4 |
| GeneCard ID
| CACNG8 |
| GenAtlas ID
| CACNG8 |
| HGNC ID
| HGNC:13628 |
| References |
|---|
| General References
| Not Available |