| Identification |
|---|
| HMDB Protein ID
| CDBP02775 |
| Secondary Accession Numbers
| Not Available |
| Name
| Signal transduction protein CBL-C |
| Description
| Not Available |
| Synonyms
|
- RING finger protein 57
- SH3-binding protein CBL-3
- SH3-binding protein CBL-C
|
| Gene Name
| CBLC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transducer activity |
| Specific Function
| Regulator of EGFR mediated signal transduction |
| GO Classification
|
| Component |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| nucleus |
| Function |
| zinc ion binding |
| protein binding |
| molecular transducer activity |
| signal transducer activity |
| calcium ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
|
| Cellular Location
|
- Nucleus (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.2 |
| SNPs
| CBLC |
| Gene Sequence
|
>1425 bp
ATGGCTCTGGCGGTGGCCCCGTGGGGGCGACAGTGGGAAGAGGCCCGCGCCCTGGGCCGG
GCAGTCAGGATGCTGCAGCGCCTAGAAGAGCAATGCGTCGACCCCCGGCTGTCCGTGAGT
CCCCCTTCGCTGCGGGACCTGCTGCCCCGCACAGCGCAGCTGCTTCGAGAGGTGGCCCAT
TCTCGGCGGGCGGCCGGCGGAGGCGGCCCCGGGGGTCCCGGCGGCTCTGGGGACTTTCTA
CTCATCTACCTGGCCAATCTGGAGGCCAAGAGCAGGCAGGTGGCCGCGCTGCTGCCTCCC
CGGGGCCGAAGGAGTGCCAACGACGAGCTCTTCCGGGCGGGCTCCAGACTCAGGCGACAG
CTGGCCAAGCTGGCCATCATCTTCAGCCACATGCACGCAGAGCTGCACGCACTCTTCCCC
GGGGGAAAGTACTGTGGACACATGTACCAGCTCACCAAGGCCCCCGCCCACACCTTCTGG
AGGGAAAGTTGCGGAGCCCGGTGTGTGCTGCCCTGGGCTGAGTTTGAGTCCCTCCTGGGC
ACCTGCCACCCTGTGGAACCAGGCTGCACAGCCCTGGCCTTGCGCACCACCATTGACCTC
ACCTGCAGCGGGCACGTGTCCATCTTCGAGTTCGACGTCTTCACCAGGCTCTTTCAGCCA
TGGCCAACACTCCTCAAGAACTGGCAGCTCCTGGCAGTCACCCACCCAGGCTACATGGCC
TTCCTCACCTATGATGAGGTCCAAGAGCGTCTGCAGGCCTGCAGAGACAAGCCAGGCAGT
TACATCTTCCGGCCCAGCTGTACTCGCCTGGGGCAGTGGGCCATCGGCTATGTGAGCTCA
GATGGCAGCATCCTGCAGACCATCCCTGCCAACAAACCCCTGTCCCAGGTGCTCCTGGAG
GGACAGAAGGACGGCTTCTACCTCTACCCAGATGGAAAGACCCACAACCCAGACCTGACT
GAGCTCGGCCAGGCAGAACCCCAGCAGCGCATCCACGTGTCAGAGGAGCAGCTGCAGCTC
TACTGGGCCATGGACTCCACATTTGAGCTCTGCAAGATCTGTGCTGAGAGCAACAAGGAT
GTGAAGATTGAGCCGTGCGGGCACCTGCTCTGCAGCTGCTGCCTGGCTGCCTGGCAGCAC
TCGGACAGCCAGACCTGCCCCTTCTGCCGCTGCGAGATCAAGGGCTGGGAGGCCGTGAGT
ATCTACCAGTTCTACGGTCAGGCTACTGCTGAGGACTCAGGGAACAGCAGTGACCAGGAA
GGCAGGGAGTTGGAGCTGGGGCAGGTGCCCCTTTCGGCTCCTCCATTGCCCCCACGGCCA
GATCTGCCCCCCAGGAAGCCCAGAAATGCCCAGCCGAAAGTGAGACTCCTAAAGGGGAAC
TCCCCTCCAGCTGCGCTGGGACCCCAGGACCCTGCCCCGGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 474 |
| Molecular Weight
| 52455.5 |
| Theoretical pI
| 7.73 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Signal transduction protein CBL-C
MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
|
| External Links |
|---|
| GenBank ID Protein
| 6291532 |
| UniProtKB/Swiss-Prot ID
| Q9ULV8 |
| UniProtKB/Swiss-Prot Entry Name
| CBLC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB028645 |
| GeneCard ID
| CBLC |
| GenAtlas ID
| CBLC |
| HGNC ID
| HGNC:15961 |
| References |
|---|
| General References
| Not Available |