| Identification |
|---|
| HMDB Protein ID
| CDBP02742 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cell adhesion molecule 3 |
| Description
| Not Available |
| Synonyms
|
- Brain immunoglobulin receptor
- IgSF4B
- Immunoglobulin superfamily member 4B
- NECL-1
- Nectin-like protein 1
- Synaptic cell adhesion molecule 3
- TSLC1-like protein 1
|
| Gene Name
| CADM3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein homodimerization activity |
| Specific Function
| Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
- Cell junction
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21.2-q22 |
| SNPs
| CADM3 |
| Gene Sequence
|
>1197 bp
ATGGGGGCCCCAGCCGCCTCGCTCCTGCTCCTGCTCCTGCTGTTCGCCTGCTGCTGGGCG
CCCGGCGGGGCCAACCTCTCCCAGGACGACAGCCAGCCCTGGACATCTGATGAAACAGTG
GTGGCTGGTGGCACCGTGGTGCTCAAGTGCCAAGTGAAAGATCACGAGGACTCATCCCTG
CAATGGTCTAACCCTGCTCAGCAGACTCTCTACTTTGGGGAGAAGAGAGCCCTTCGAGAT
AATCGAATTCAGCTGGTTACCTCTACGCCCCACGAGCTCAGCATCAGCATCAGCAATGTG
GCCCTGGCAGACGAGGGCGAGTACACCTGCTCAATCTTCACTATGCCTGTGCGAACTGCC
AAGTCCCTCGTCACTGTGCTAGGAATTCCACAGAAGCCCATCATCACTGGTTATAAATCT
TCATTACGGGAAAAAGACACAGCCACCCTAAACTGTCAGTCTTCTGGGAGCAAGCCTGCA
GCCCGGCTCACCTGGAGAAAGGGTGACCAAGAACTCCACGGAGAACCAACCCGCATACAG
GAAGATCCCAATGGTAAAACCTTCACTGTCAGCAGCTCGGTGACATTCCAGGTTACCCGG
GAGGATGATGGGGCGAGCATCGTGTGCTCTGTGAACCATGAATCTCTAAAGGGAGCTGAC
AGATCCACCTCTCAACGCATTGAAGTTTTATACACACCAACTGCGATGATTAGGCCAGAC
CCTCCCCATCCTCGTGAGGGCCAGAAGCTGTTGCTACACTGTGAGGGTCGCGGCAATCCA
GTCCCCCAGCAGTACCTATGGGAGAAGGAGGGCAGTGTGCCACCCCTGAAGATGACCCAG
GAGAGTGCCCTGATCTTCCCTTTCCTCAACAAGAGTGACAGTGGCACCTACGGCTGCACA
GCCACCAGCAACATGGGCAGCTACAAGGCCTACTACACCCTCAATGTTAATGACCCCAGT
CCGGTGCCCTCCTCCTCCAGCACCTACCACGCCATCATCGGTGGGATCGTGGCTTTCATT
GTCTTCCTGCTGCTCATCATGCTCATCTTCCTTGGCCACTACTTGATCCGGCACAAAGGA
ACCTACCTGACACATGAGGCAAAAGGCTCCGACGATGCTCCAGACGCGGACACGGCCATC
ATCAATGCAGAAGGCGGGCAGTCAGGAGGGGACGACAAGAAGGAATATTTCATCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 398 |
| Molecular Weight
| 43299.5 |
| Theoretical pI
| 6.0 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cell adhesion molecule 3
MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL
QWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTA
KSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQ
EDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD
PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT
ATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKG
TYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI
|
| External Links |
|---|
| GenBank ID Protein
| 187608363 |
| UniProtKB/Swiss-Prot ID
| Q8N126 |
| UniProtKB/Swiss-Prot Entry Name
| CADM3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001127173.1 |
| GeneCard ID
| CADM3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |