| Identification |
| HMDB Protein ID
| CDBP02741 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-related family member 4 |
| Description
| Not Available |
| Synonyms
|
- Cadherin-like protein 29
|
| Gene Name
| CDHR4 |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p21.31 |
| SNPs
| CDHR4 |
| Gene Sequence
|
>2367 bp
ATGGTGCTGCTCAGGCTCCTCGTGTTCCTCTTTGCTCCGGTGGTCTCTGACCTCTGCAGC
CTGCCCTGCTTTATAAATGTCTCTGAGAGCCAGGGCCCTGGCACAGTCCTTCAGTTTTTA
TCCTTCAACTGCTCCTCCTACACGCCCACACCCACCCTGGAGTTGCTCAATGTCCAGCCA
CCCACCACCTTCTTCAACCCACCCAGCTTGGCCAGGTGGCAAGGGACCTATGTGGGCAAG
TTGACCTTGAGCAGCTCTGCTCAGTTGGATGCCCTGATGGTGAACCACTACAAGGTGCAG
CTGAAGTTCACATGTGGCAACCATGTGATGGAGGGCTCACTCTCTGTGGATGTGCAGCGG
GACCTTAGCCATATCCAGTGTGCTGGTCAATTTGCCAGCCCAGCTGGGGAAATGATTCAG
GTGCCAGAGACAGTCACACCTGGGGCTCGGCTGTACACTCTGCTCCTCCCAGGCCTAGAA
CTCCACGGAGCGCAGATGAGCATTATCAGTGCCCAGGACCTGCCACACTTCCCTGGACCT
TTCTCCATCAATGAGCAAGGTTGGCTGCAGGCACCATCCCAGGGCCTCCTAGGCCAGGCT
CAAAAGGTCTTCCAGCTGCAAATCTCAGTGTCCTTTGGACAAAGGCAAAGCTGCCAAGGG
ATGGTGATAGTGAAGGTTTTGCCTGTTCCCTCCAGCCAGGTCTCCTTCCTCGAGCAGGCT
CAGAATATCACCATCCCTGAGAATCTGGCCCCCGGTAGTGAGGTGGTTCAGGTCCAGGCC
CGGGGTGTCGACCTGCGCTATGAAATCCTGTCTCCGGTGCCCAGCCCACTCTTCTCCATT
GGTCGTGCAGACGGTGTGGTCCGGACCACCACGCCCCTAGAGTTAGCTCGCACCTCAGGC
ACCGCGGTCTCCAGGCTGCAGGTGAAGGCCTTTGAGCAGGGCCAGCTGTGGGCCAGTGCC
AAGCTCAATCTCACCATGAATGTGCAGCTGGTCAACCTCTGGCCTCCACGCTGCCTCCCA
GCGCTTCTGGTGTCCCAAATCCCGGAGACTGCACCCGTGGGCACCGTGCTGAATACTCTC
ACTTGCGAAGATCCGGACTCTGTTGGTGCCACCCTGGACTACAAGCTGTGGTTCCGCAGC
TCTTCCAACCCTGCCAGCCTCTGCCTTTATGACAGAGTCCTTGAGGTGAATGCCACACTG
GACTGTGACACTCCTGGAGCCTGCTTCCAGCATGCAGCCTCCATCCTGGTGCTCGATGGT
GGCCAGCCCCAGATGACCACTGAGGTGCCGGTACTGGTGATGGTGACACCCATCAACGAG
TTCTCCCCAGCCTGTGCCCCTCGCACGTTCCGGGTTCAGGAGGATGCGGCGCCCCACACT
CTACTGGGCTCCGTGGTGGGCACGGATATGGATTACCCTCACGACAACATTGAGTACTAC
ACCTCTGGTGGTCCTACCACCTTTGCTGTGGACCGTCTCAGCGGGGAAGTTCACCTCCTG
GGACCTTTGGACTATGAGCAGCAGAGGCTGTACAGGCTCACTGTCCTTGTGATTGACCAT
GGCCAAGACCAGAACCCCAACCATCACCTCTCAGGCTCCTGTACCATTACCATCGAGGTT
GAGGATGTGAATGACCATGCCCCCGAGTGTGAGCCCCCATTTCAGGAACTCACCATCTAT
GCTCCTCTGGGCCGTAGCGTGGAGGTGACCAAGATGTCATGCCAGATCCCTCAGGAGCCA
CAGCGCCTGATCTACTCCTATAGCATCGTGGGAGGGAATAGCCAGAACCGATTCATCCTG
CAAGGGGCCATCCTGGTGCACAGTGACCTTGTGTTGGGGCCGTTCTGGCCAGAGCAGCCC
CGTACCTATGAGCTACTGATCTGTGTGGCCGATGCAGGCCCCTCCACCCCCCACCTCAGC
ACCACAGCCACCATTATTGTGCATCTAGTTCCCCGGAGGGCCAGCACAGTGGCCACCAGC
ACCCACAGAACCACAGTGCCCTCAACGATGACACCCATGCTCGTGACAGACACAGAGGCT
TTCTGGCAGCCACAGCCCTGGTTTGTGGTGGTGTTGACAGCAACTGGTGCTCTTCTCCTC
TTGGCCCTAGGCTGGCTTCTTGGCAGGCTCCTCCAGGGGTTGGCCCAGCTGCTGCAAGCA
CCCAGCAAACCAGCCCAGGCTTTGCTGCTAAACAGCATCCAGGGAACTGAGGGATCCATC
GAGGGTTTCCTGGAGGCACCGAAGATGGAGATGTCCCAGGCACCCAGCAGTGTCATGAGT
CTGCATTTTGATGGCAGAGCACAGGACTCCCGTACCGGAAGAGACTACCTGTTTAACACA
CACACAGGAGCCCGGCGCTGGCTCTGA
|
| Protein Properties |
| Number of Residues
| 788 |
| Molecular Weight
| 85826.6 |
| Theoretical pI
| 5.13 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-related family member 4
MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQP
PTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQR
DLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGP
FSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQA
QNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSG
TAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTL
TCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDG
GQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYY
TSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEV
EDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFIL
QGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATS
THRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQA
PSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMSLHFDGRAQDSRTGRDYLFNT
HTGARRWL
|
| External Links |
| GenBank ID Protein
| 203097724 |
| UniProtKB/Swiss-Prot ID
| A6H8M9 |
| UniProtKB/Swiss-Prot Entry Name
| CDHR4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001007540.2 |
| GeneCard ID
| CDHR4 |
| GenAtlas ID
| CDHR4 |
| HGNC ID
| HGNC:34527 |
| References |
| General References
| Not Available |