| Identification |
|---|
| HMDB Protein ID
| CDBP02738 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-7 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CDH7 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q22.1 |
| SNPs
| CDH7 |
| Gene Sequence
|
>2358 bp
ATGAAGTTGGGCAAAGTGGAGTTCTGCCATTTTCTGCAGCTAATAGCTCTTTTCCTGTGT
TTTTCTGGGATGAGTCAAGCAGAACTCTCAAGGTCCAGATCAAAGCCCTATTTCCAATCA
GGGAGGTCCCGGACCAAGCGCAGCTGGGTGTGGAATCAGTTCTTTGTGCTGGAGGAATAC
ATGGGTTCAGACCCCCTCTATGTAGGAAAGCTTCACTCTGATGTTGATAAAGGAGATGGT
TCCATCAAATACATCTTGTCAGGCGAAGGGGCAAGTTCCATTTTCATTATTGATGAGAAC
ACTGGGGATATTCATGCCACCAAGAGACTGGATCGTGAGGAGCAGGCCTACTACACGCTC
CGAGCTCAAGCGCTGGATAGGCTCACCAACAAACCCGTGGAGCCCGAGTCGGAGTTTGTC
ATCAAAATTCAGGATATCAACGACAATGAACCCAAATTTTTGGATGGCCCATACACGGCA
GGAGTTCCCGAAATGTCTCCCGTGGGGACCTCAGTGGTACAAGTGACAGCGACGGATGCT
GATGATCCTACATATGGCAACAGTGCCAGAGTGGTCTACAGTATTCTGCAAGGACAGCCG
TACTTCTCAGTGGAGCCAAAGACAGGAGTCATCAAGACTGCCCTTCCAAACATGGATAGA
GAGGCTAAAGACCAGTATTTGCTTGTTATTCAGGCAAAGGATATGGTTGGTCAAAATGGA
GGACTGTCAGGAACTACATCAGTCACTGTGACCCTAACTGATGTCAACGATAATCCACCT
CGCTTTCCTCGAAGGTCTTATCAATATAACGTCCCAGAGTCATTACCTGTAGCCTCAGTT
GTGGCCAGAATTAAAGCTGCTGATGCAGATATTGGAGCTAATGCTGAAATGGAGTACAAG
ATTGTGGATGGTGATGGTTTGGGCATTTTTAAGATTTCTGTTGACAAAGAAACCCAGGAA
GGAATCATTACTATACAGAAGGAGCTGGATTTTGAAGCCAAAACAAGTTACACGCTACGG
ATAGAAGCTGCAAATAAAGATGCCGACCCTCGCTTTCTGAGCTTGGGTCCGTTCAGTGAC
ACGACAACTGTGAAGATAATTGTGGAAGATGTAGATGAGCCCCCTGTGTTCTCTTCACCC
TTGTACCCTATGGAGGTGTCGGAAGCTACCCAGGTTGGGAATATCATTGGCACTGTAGCA
GCTCATGACCCAGATTCTTCCAATAGCCCTGTGAGGTACTCAATTGACAGAAACACAGAC
TTGGAGAGATACTTCAATATTGATGCCAACAGTGGGGTCATCACAACTGCCAAGTCTTTG
GATCGAGAGACAAATGCTATTCACAATATCACAGTCCTTGCAATGGAGAGCCAGAATCCA
TCTCAAGTAGGAAGAGGCTATGTGGCCATCACTATACTTGACATCAATGATAACGCCCCT
GAATTTGCCATGGACTATGAGACCACCGTCTGTGAAAATGCCCAGCCGGGGCAGGTTATC
CAGAAAATCAGTGCTGTGGATAAAGATGAGCCATCCAATGGACACCAGTTTTACTTCAGC
TTAACAACGGATGCAACAAATAACCACAACTTTTCATTGAAAGATAACAAAGACAACACA
GCCTCAATACTGACCAGGAGAAACGGCTTCCGGAGACAGGAACAATCAGTTTACTATCTG
CCAATTTTCATTGTGGACAGTGGATCTCCCTCACTTAGCAGCACCAGCACCCTCACCATC
CGCGTGTGTGACTGTGATGCTGACGGCGTAGCCCAGACCTGCAATGCAGAGGCCTATGTC
CTACCTGCTGGCCTCAGTACAGGAGCCCTGATAGCCATACTCGCCTGTGTCTTGACATTA
TTGGTGTTGATCCTCCTTATCGTCACTATGAGAAGACGGAAAAAAGAGCCCCTTATTTTT
GACGAAGAAAGAGACATCAGAGAAAATATTGTGAGATACGATGACGAGGGCGGGGGAGAG
GAGGACACGGAAGCGTTTGACATGGCTGCACTGAGAAACCTCAACGTCATCCGAGACACC
AAGACCCGGAGGGATGTGACTCCAGAAATTCAATTCCTGAGTCGACCAGCTTTTAAAAGC
ATCCCAGATAATGTCATCTTTAGGGAATTTATTTGGGAAAGATTAAAAGAAGCCGATGTT
GATCCTGGTGCTCCTCCTTATGACTCCCTGCAGACATATGCTTTTGAAGGAAATGGCTCA
GTTGCTGAATCACTCAGCTCTTTAGATTCCATCAGCTCAAACTCTGATCAGAACTATGAC
TACCTAAGTGACTGGGGACCTCGCTTTAAACGACTCGCGGACATGTATGGGACTGGCCAA
GAGAGTTTGTACTCATAG
|
| Protein Properties |
|---|
| Number of Residues
| 785 |
| Molecular Weight
| 87085.5 |
| Theoretical pI
| 4.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-7
MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEY
MGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTL
RAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDA
DDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNG
GLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYK
IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSD
TTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTD
LERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAP
EFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNT
ASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYV
LPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGE
EDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADV
DPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQ
ESLYS
|
| External Links |
|---|
| GenBank ID Protein
| 6483290 |
| UniProtKB/Swiss-Prot ID
| Q9ULB5 |
| UniProtKB/Swiss-Prot Entry Name
| CADH7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB035301 |
| GeneCard ID
| CDH7 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |