| Identification |
|---|
| HMDB Protein ID
| CDBP02727 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-20 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CDH20 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q21.33 |
| SNPs
| CDH20 |
| Gene Sequence
|
>2406 bp
ATGTGGACTTCTGGTAGAATGAGCAATGCAAAGAACTGGCTTGGACTTGGCATGTCCTTG
TACTTCTGGGGGCTGATGGACCTTACGACCACCGTTCTCTCGGACACCCCAACACCACAA
GGTGAATTAGAAGCACTCCTGTCAGACAAGCCACAGTCACATCAGCGGACCAAGAGGAGC
TGGGTTTGGAACCAGTTTTTCGTTCTGGAAGAGTACACTGGGACCGACCCTTTGTATGTC
GGCAAGCTTCATTCAGATATGGACAGGGGAGACGGATCCATCAAATACATCCTCTCGGGA
GAAGGTGCTGGCATCGTGTTTACCATCGACGACACCACTGGAGACATCCACGCCATTCAG
AGGCTCGACCGAGAGGAAAGAGCCCAGTATACTCTAAGGGCTCAAGCCCTAGACAGGCGG
ACGGGCAGGCCAATGGAGCCCGAGTCAGAGTTCATCATCAAAATTCAAGACATCAATGAC
AATGAGCCCAAGTTCCTGGACGGACCTTATGTGGCCACTGTGCCAGAAATGTCCCCTGTG
GGTACCTCCGTCATCCAAGTGACAGCCACAGATGCAGATGACCCGACCTACGGCAACAGT
GCCAGGGTGGTGTACAGCATTCTTCAGGGCCAGCCATATTTTTCTGTGGACTCTAAAACA
GGTGTAATTAGGACAGCGCTCATGAACATGGACAGAGAAGCCAAAGAATACTACGAAGTG
ATTATCCAAGCCAAGGACATGGGAGGGCAGCTTGGAGGATTAGCTGGGACCACAACAGTC
AACATCACCCTCTCAGATGTCAATGATAACCCACCCCGCTTTCCCCAGAAACATTACCAG
ATGAGTGTGTTGGAATCAGCTCCAATTAGCTCCACTGTCGGGAGAGTGTTTGCCAAGGAC
TTGGATGAAGGCATCAATGCAGAGATGAAATATACTATTGTGGATGGAGATGGTGCAGAT
GCCTTTGACATTAGCACAGATCCCAATTTCCAAGTTGGTATCATAACTGTGAAGAAGCCC
CTGAGTTTTGAAAGCAAGAAAAGCTACACCTTAAAGGTGGAGGGAGCCAATCCTCACCTA
GAGATGCGTTTTCTGAACTTGGGCCCATTTCAGGACACAACAACAGTGCACATCAGTGTG
GAAGACGTGGACGAGCCCCCTGTGTTTGAACCTGGCTTTTACTTTGTGGAGGTGCCTGAG
GATGTGGCGATTGGAACAACCATACAGATCATTTCTGCCAAGGACCCAGATGTGACCAAC
AACTCAATCAGATACTCCATTGATAGAAGCAGTGACCCTGGAAGATTTTTCTATGTTGAC
ATTACAACAGGTGCCCTAATGACAGCAAGACCCCTAGACCGGGAAGAATTTTCTTGGCAT
AATATCACTGTCCTTGCTATGGAAATGAACAATCCCTCCCAGGTTGGAAGTGTTCCTGTC
ACAATCAAAGTCTTAGATGTGAATGACAATGCTCCAGAGTTCCCCAGATTCTATGAAGCT
TTTGTCTGTGAGAACGCCAAGGCAGGACAGCTGATCCAGACAGTGAGTGCGGTGGACCAA
GATGACCCACGCAATGGTCAGCATTTCTACTACAGCTTGGCTCCTGAGGCTGCTAACAAC
CCCAACTTTACCATAAGGGACAACCAAGATAACACAGCACGGATTCTAACCAGGAGGTCT
GGTTTCCGGCAGCAGGAGCAGAGTGTCTTTCACCTGCCTATCCTGATAGCAGATAGCGGG
CAGCCCGTGCTGAGCAGCACAGGCACACTGACCATCCAAGTGTGCAGCTGTGATGACGAC
GGCCACGTCATGTCCTGCAGCCCAGAGGCCTACATGCTCCCAGTCAGTTTGAGCCGGGGC
CCCCTCATTGCCATCCTCGCCTGCATCTTTGTCCTCCTAGTGCTGGTGTTGCTCATTTTG
TCCATGAGGCGGCACCGGAAACAACCATACATCATCGACGACGAGGAAAACATCCACGAG
AACATCGTCCGCTACGACGACGAGGGCGGCGGCGAGGAGGACACCGAGGCCTTCGACATC
GCGGCCATGTGGAACCCCCGGGAGGCGCAGGCGGGGGCCGGCCCCAAGACGCGGCAGGAC
ATGCTGCCCGAGATCGAGAGCCTCTTCCGCTACGTGCCTCAGACGTGCGCAGTGAACAGC
ACTGTCCACAGCTACGTGCTGGCCAAGCTCTACGAGGCCGACATGGACCTGTGGACACCG
CCCTTCGACTCCCTCCAGACGTATATGTTCGAGGGGGACGGCCCTGTGGCGGGGTCGCTG
AGCTCCCTGCAGTCGGCCACGTCGGACTCGGAACAGAGCTTCGACTTCCTGACGGACTGG
GGGCCCCGCTTCCGGAAGCTGGCCGAGCTCTACGGGGCGTCGGAGGGACCCGCGCCGCTG
TGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 801 |
| Molecular Weight
| 88992.0 |
| Theoretical pI
| 4.3 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-20
MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRS
WVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQ
RLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPV
GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV
IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD
LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL
EMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN
NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV
TIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN
PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD
GHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHE
NIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNS
TVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDW
GPRFRKLAELYGASEGPAPLW
|
| External Links |
|---|
| GenBank ID Protein
| 10834607 |
| UniProtKB/Swiss-Prot ID
| Q9HBT6 |
| UniProtKB/Swiss-Prot Entry Name
| CAD20_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF217289 |
| GeneCard ID
| CDH20 |
| GenAtlas ID
| CDH20 |
| HGNC ID
| HGNC:1760 |
| References |
|---|
| General References
| Not Available |