| Identification |
|---|
| HMDB Protein ID
| CDBP02726 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-19 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CDH19 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| plasma membrane |
| membrane |
| cell part |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q22.1 |
| SNPs
| CDH19 |
| Gene Sequence
|
>2319 bp
ATGAACTGTTATTTACTGCTGCGTTTTATGTTGGGAATTCCTCTCCTATGGCCTTGTCTT
GGAGCAACAGAAAACTCTCAAACAAAGAAAGTCAAGCAGCCAGTGCGATCTCATTTGAGA
GTGAAGCGTGGCTGGGTGTGGAACCAATTTTTTGTACCAGAGGAAATGAATACGACTAGT
CATCACATCGGCCAGCTAAGATCTGATTTAGACAATGGAAACAATTCTTTCCAGTACAAG
CTTTTGGGAGCTGGAGCTGGAAGTACTTTTATCATTGATGAAAGAACAGGTGACATATAT
GCCATACAGAAGCTTGATAGAGAGGAGCGATCCCTCTACATCTTAAGAGCCCAGGTAATA
GACATCGCTACTGGAAGGGCTGTGGAACCTGAGTCTGAGTTTGTCATCAAAGTTTCGGAT
ATCAATGACAATGAACCAAAATTCCTAGATGAACCTTATGAGGCCATTGTACCAGAGATG
TCTCCAGAAGGAACATTAGTTATCCAGGTGACAGCAAGTGATGCTGACGATCCCTCAAGT
GGTAATAATGCTCGTCTCCTCTACAGCTTACTTCAAGGCCAGCCATATTTTTCTGTTGAA
CCAACAACAGGAGTCATAAGAATATCTTCTAAAATGGATAGAGAACTGCAAGATGAGTAT
TGGGTAATCATTCAAGCCAAGGACATGATTGGTCAGCCAGGAGCGTTGTCTGGAACAACA
AGTGTATTAATTAAACTTTCAGATGTTAATGACAATAAGCCTATATTTAAAGAAAGTTTA
TACCGCTTGACTGTCTCTGAATCTGCACCCACTGGGACTTCTATAGGAACAATCATGGCA
TATGATAATGACATAGGAGAGAATGCAGAAATGGATTACAGCATTGAAGAGGATGATTCG
CAAACATTTGACATTATTACTAATCATGAAACTCAAGAAGGAATAGTTATATTAAAAAAG
AAAGTGGATTTTGAGCACCAGAACCACTACGGTATTAGAGCAAAAGTTAAAAACCATCAT
GTTCCTGAGCAGCTCATGAAGTACCACACTGAGGCTTCCACCACTTTCATTAAGATCCAG
GTGGAAGATGTTGATGAGCCTCCTCTTTTCCTCCTTCCATATTATGTATTTGAAGTTTTT
GAAGAAACCCCACAGGGATCATTTGTAGGCGTGGTGTCTGCCACAGACCCAGACAATAGG
AAATCTCCTATCAGGTATTCTATTACTAGGAGCAAAGTGTTCAATATCAATGATAATGGT
ACAATCACTACAAGTAACTCACTGGATCGTGAAATCAGTGCTTGGTACAACCTAAGTATT
ACAGCCACAGAAAAATACAATATAGAACAGATCTCTTCGATCCCACTGTATGTGCAAGTT
CTTAACATCAATGATCATGCTCCTGAGTTCTCTCAATACTATGAGACTTATGTTTGTGAA
AATGCAGGCTCTGGTCAGGTAATTCAGACTATCAGTGCAGTGGATAGAGATGAATCCATA
GAAGAGCACCATTTTTACTTTAATCTATCTGTAGAAGACACTAACAATTCAAGTTTTACA
ATCATAGATAATCAAGATAACACAGCTGTCATTTTGACTAATAGAACTGGTTTTAACCTT
CAAGAAGAACCTGTCTTCTACATCTCCATCTTAATTGCCGACAATGGAATCCCGTCACTT
ACAAGTACAAACACACTTACCATCCATGTCTGTGACTGTGGTGACAGTGGGAGCACACAG
ACCTGCCAGTACCAGGAGCTTGTGCTTTCCATGGGATTCAAGACAGAAGTCATCATTGCT
ATTCTCATTTGCATTATGATCATATTTGGGTTTATTTTTTTGACTTTGGGTTTAAAACAA
CGGAGAAAACAGATTCTATTTCCTGAGAAAAGTGAAGATTTCAGAGAGAATATATTCCAA
TATGATGATGAAGGGGGTGGAGAAGAAGATACAGAGGCCTTTGATATAGCAGAGCTGAGG
AGTAGTACCATAATGCGGGAACGCAAGACTCGGAAAACCACAAGCGCTGAGATCAGGAGC
CTATACAGGCAGTCTTTGCAAGTTGGCCCCGACAGTGCCATATTCAGGAAATTCATTCTG
GAAAAGCTCGAAGAAGCTAATACTGATCCGTGTGCCCCTCCTTTTGATTCCCTCCAGACC
TACGCTTTTGAGGGAACAGGGTCATTAGCTGGATCCCTGAGCTCCTTAGAATCAGCAGTC
TCTGATCAGGATGAAAGCTATGATTACCTTAATGAGTTGGGACCTCGCTTTAAAAGATTA
GCATGCATGTTTGGTTCTGCAGTGCAGTCAAATAATTAG
|
| Protein Properties |
|---|
| Number of Residues
| 772 |
| Molecular Weight
| 87001.6 |
| Theoretical pI
| 4.35 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-19
MNCYLLLRFMLGIPLLWPCLGATENSQTKKVKQPVRSHLRVKRGWVWNQFFVPEEMNTTS
HHIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVI
DIATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSS
GNNARLLYSLLQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTT
SVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDS
QTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQ
VEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNRKSPIRYSITRSKVFNINDNG
TITTSNSLDREISAWYNLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCE
NAGSGQVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNL
QEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIA
ILICIMIIFGFIFLTLGLKQRRKQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELR
SSTIMRERKTRKTTSAEIRSLYRQSLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQT
YAFEGTGSLAGSLSSLESAVSDQDESYDYLNELGPRFKRLACMFGSAVQSNN
|
| External Links |
|---|
| GenBank ID Protein
| 10803406 |
| UniProtKB/Swiss-Prot ID
| Q9H159 |
| UniProtKB/Swiss-Prot Entry Name
| CAD19_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ007607 |
| GeneCard ID
| CDH19 |
| GenAtlas ID
| CDH19 |
| HGNC ID
| HGNC:1758 |
| References |
|---|
| General References
| Not Available |