| Identification |
|---|
| HMDB Protein ID
| CDBP02720 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-11 |
| Description
| Not Available |
| Synonyms
|
- OB-cadherin
- OSF-4
- Osteoblast cadherin
|
| Gene Name
| CDH11 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| calcium ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q22.1 |
| SNPs
| CDH11 |
| Gene Sequence
|
>2391 bp
ATGAAGGAGAACTACTGTTTACAAGCCGCCCTGGTGTGCCTGGGCATGCTGTGCCACAGC
CATGCCTTTGCCCCAGAGCGGCGGGGGCACCTGCGGCCCTCCTTCCATGGGCACCATGAG
AAGGGCAAGGAGGGGCAGGTGCTACAGCGCTCCAAGCGTGGCTGGGTCTGGAACCAGTTC
TTCGTGATAGAGGAGTACACCGGGCCTGACCCCGTGCTTGTGGGCAGGCTTCATTCAGAT
ATTGACTCTGGTGATGGGAACATTAAATACATTCTCTCAGGGGAAGGAGCTGGAACCATT
TTTGTGATTGATGACAAATCAGGGAACATTCATGCCACCAAGACGTTGGATCGAGAAGAG
AGAGCCCAGTACACGTTGATGGCTCAGGCGGTGGACAGGGACACCAATCGGCCACTGGAG
CCACCGTCGGAATTCATTGTCAAGGTCCAGGACATTAATGACAACCCTCCGGAGTTCCTG
CACGAGACCTATCATGCCAACGTGCCTGAGAGGTCCAATGTGGGAACGTCAGTAATCCAG
GTGACAGCTTCAGATGCAGATGACCCCACTTATGGAAATAGCGCCAAGTTAGTGTACAGT
ATCCTCGAAGGACAACCCTATTTTTCGGTGGAAGCACAGACAGGTATCATCAGAACAGCC
CTACCCAACATGGACAGGGAGGCCAAGGAGGAGTACCACGTGGTGATCCAGGCCAAGGAC
ATGGGTGGACATATGGGCGGACTCTCAGGGACAACCAAAGTGACGATCACACTGACCGAT
GTCAATGACAACCCACCAAAGTTTCCGCAGAGCGTATACCAGATGTCTGTGTCAGAAGCA
GCCGTCCCTGGGGAGGAAGTAGGAAGAGTGAAAGCTAAAGATCCAGACATTGGAGAAAAT
GGCTTAGTCACATACAATATTGTTGATGGAGATGGTATGGAATCGTTTGAAATCACAACG
GACTATGAAACACAGGAGGGGGTGATAAAGCTGAAAAAGCCTGTAGATTTTGAAACCAAA
AGAGCCTATAGCTTGAAGGTAGAGGCAGCCAACGTGCACATCGACCCGAAGTTTATCAGC
AATGGCCCTTTCAAGGACACTGTGACCGTCAAGATCTCAGTAGAAGATGCTGATGAGCCC
CCTATGTTCTTGGCCCCAAGTTACATCCACGAAGTCCAAGAAAATGCAGCTGCTGGCACC
GTGGTTGGGAGAGTGCATGCCAAAGACCCTGATGCTGCCAACAGCCCGATAAGGTATTCC
ATCGATCGTCACACTGACCTCGACAGATTTTTCACTATTAATCCAGAGGATGGTTTTATT
AAAACTACAAAACCTCTGGATAGAGAGGAAACAGCCTGGCTCAACATCACTGTCTTTGCA
GCAGAAATCCACAATCGGCATCAGGAAGCCAAAGTCCCAGTGGCCATTAGGGTCCTTGAT
GTCAACGATAATGCTCCCAAGTTTGCTGCCCCTTATGAAGGTTTCATCTGTGAGAGTGAT
CAGACCAAGCCACTTTCCAACCAGCCAATTGTTACAATTAGTGCAGATGACAAGGATGAC
ACGGCCAATGGACCAAGATTTATCTTCAGCCTACCCCCTGAAATCATTCACAATCCAAAT
TTCACAGTCAGAGACAACCGAGATAACACAGCAGGCGTGTACGCCCGGCGTGGAGGGTTC
AGTCGGCAGAAGCAGGACTTGTACCTTCTGCCCATAGTGATCAGCGATGGCGGCATCCCG
CCCATGAGTAGCACCAACACCCTCACCATCAAAGTCTGCGGGTGCGACGTGAACGGGGCA
CTGCTCTCCTGCAACGCAGAGGCCTACATTCTGAACGCCGGCCTGAGCACAGGCGCCCTG
ATCGCCATCCTCGCCTGCATCGTCATTCTCCTGGTCATTGTAGTATTGTTTGTGACCCTG
AGAAGGCAAAAGAAAGAACCACTCATTGTCTTTGAGGAAGAAGATGTCCGTGAGAACATC
ATTACTTATGATGATGAAGGGGGTGGGGAAGAAGACACAGAAGCCTTTGATATTGCCACC
CTCCAGAATCCTGATGGTATCAATGGATTTATCCCCCGCAAAGACATCAAACCTGAGTAT
CAGTACATGCCTAGACCTGGGCTCCGGCCAGCGCCCAACAGCGTGGATGTCGATGACTTC
ATCAACACGAGAATACAGGAGGCAGACAATGACCCCACGGCTCCTCCTTATGACTCCATT
CAAATCTACGGTTATGAAGGCAGGGGCTCAGTGGCCGGGTCCCTGAGCTCCCTAGAGTCG
GCCACCACAGATTCAGACTTGGACTATGATTATCTACAGAACTGGGGACCTCGTTTTAAG
AAACTAGCAGATTTGTATGGTTCCAAAGACACTTTTGATGACGATTCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 796 |
| Molecular Weight
| 87964.5 |
| Theoretical pI
| 4.51 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-11
MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF
FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE
RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ
VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD
MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN
GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS
NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS
IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD
VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN
FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA
LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI
ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF
INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK
KLADLYGSKDTFDDDS
|
| External Links |
|---|
| GenBank ID Protein
| 16306532 |
| UniProtKB/Swiss-Prot ID
| P55287 |
| UniProtKB/Swiss-Prot Entry Name
| CAD11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001797.2 |
| GeneCard ID
| CDH11 |
| GenAtlas ID
| CDH11 |
| HGNC ID
| HGNC:1750 |
| References |
|---|
| General References
| Not Available |