| Identification |
| HMDB Protein ID
| CDBP02705 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcium-binding tyrosine phosphorylation-regulated protein |
| Description
| Not Available |
| Synonyms
|
- CT88
- Calcium-binding protein 86
- Cancer/testis antigen 88
- FSP-2
- Fibrousheathin II
- Fibrousheathin-2
- Testis-specific calcium-binding protein CBP86
|
| Gene Name
| CABYR |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in cAMP-dependent protein kinase regulator activity |
| Specific Function
| May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium |
| GO Classification
|
| Function |
| enzyme regulator activity |
| kinase regulator activity |
| protein kinase regulator activity |
| camp-dependent protein kinase regulator activity |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
- Cytoplasm
- Cell projection
- cilium
- Isoform 5:Nucleus
- flagellum
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q11.2 |
| SNPs
| CABYR |
| Gene Sequence
|
>1482 bp
ATGATTTCTTCAAAGCCCAGACTTGTCGTACCCTATGGCCTCAAGACTCTGCTCGAGGGA
ATTAGCAGAGCTGTTCTCAAAACCAACCCATCAAACATCAACCAGTTTGCAGCAGCTTAT
TTTCAAGAACTTACTATGTATAGAGGGAATACTACTATGGATATAAAAGATCTGGTTAAA
CAATTTCATCAGATTAAAGTAGAGAAATGGTCAGAAGGAACGACACCACAGAAGAAATTA
GAATGTTTAAAAGAACCAGGAAAAACATCTGTAGAATCTAAAGTACCTACCCAGATGGAA
AAATCTACAGACACAGACGAGGACAATGTAACCAGAACAGAATATAGTGACAAAACCACC
CAGTTTCCATCAGTTTATGCTGTGCCAGGCACTGAGCAAACGGAAGCAGTTGGTGGTCTT
TCTTCCAAACCAGCCACCCCTAAGACTACTACCCCACCCTCATCACCACCTCCAACAGCT
GTCTCACCAGAGTTTGCCTACGTCCCAGCTGACCCAGCTCAGCTTGCTGCTCAGATGTTA
GGTAAAGTTTCATCTATTCATTCTGATCAATCTGATGTGTTAATGGTGGATGTGGCAACC
AGTATGCCTGTTGTTATCAAGGAGGTGCCAAGCTCAGAGGCTGCTGAAGATGTCATGGTG
GCTGCTCCTCTTGTGTGTTCTGGAAAGGTGCTAGAAGTGCAGGTTGTGAACCAAACATCT
GTCCATGTAGATTTGGGTTCTCAACCTAAAGAAAATGAGGCTGAACCATCAACGGCTTCC
TCAGTCCCCTTGCAGGATGAACAAGAACCTCCTGCTTATGATCAAGCTCCTGAGGTCACT
TTGCAGGCTGATATTGAGGTTATGTCAACTGTTCATATATCATCTGTCTATAACGATGTG
CCTGTGACTGAAGGAGTTGTTTATATCGAGCAACTGCCAGAACAAATAGTTATCCCTTTT
ACTGATCAAGTTGCTTGTCTTAAAGAAAATGAGCAGTCAAAAGAAAATGAGCAGTCACCA
CGAGTTAGTCCCAAATCTGTAGTAGAAAAGACCACCTCTGGCATGTCTAAAAAATCTGTA
GAGTCCGTAAAACTTGCACAGTTGGAGGAGAATGCAAAATATTCCTCAGTATATATGGAG
GCAGAAGCAACAGCTCTGCTCTCTGACACATCTTTGAAAGGTCAGCCTGAGGTACCTGCA
CAACTCCTGGATGCAGAAGGTGCTATCAAAATAGGCTCTGAAAAATCTCTGCACCTTGAA
GTGGAGGTCACTTCAATAGTCTCTGACAATACTGGGCAGGAGGAGTCTGGGGAAAACTCT
GTACCCCAGGAGATGGAAGGCAGACCTGTGCTCTCTGGGGAAGCTGCAGAAGCAGTGCAC
TCAGGTACATCTGTAAAGTCATCTAGTGGCCCCTTCCCTCCTGCTCCAGAAGGCCTTACT
GCACCAGAAATTGAACCAGAAGGGGAATCAACAGCTGAATAA
|
| Protein Properties |
| Number of Residues
| 493 |
| Molecular Weight
| 52773.6 |
| Theoretical pI
| 4.2 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calcium-binding tyrosine phosphorylation-regulated protein
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK
QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS
VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV
PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV
ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE
VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT
APEIEPEGESTAE
|
| External Links |
| GenBank ID Protein
| 3599530 |
| UniProtKB/Swiss-Prot ID
| O75952 |
| UniProtKB/Swiss-Prot Entry Name
| CABYR_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF088868 |
| GeneCard ID
| CABYR |
| GenAtlas ID
| CABYR |
| HGNC ID
| HGNC:15569 |
| References |
| General References
| Not Available |