| Identification |
|---|
| HMDB Protein ID
| CDBP02690 |
| Secondary Accession Numbers
| Not Available |
| Name
| B box and SPRY domain-containing protein |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| BSPRY |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| May regulate epithelial calcium transport by inhibiting TRPV5 activity |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
|
| Cellular Location
|
- Cytoplasm
- Peripheral membrane protein
- Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q32 |
| SNPs
| BSPRY |
| Gene Sequence
|
>1209 bp
ATGTCCGCCGAGGGCGCGGAGCCGGGGCCGGGGTCCGGGTCCGGGCCCGGGCCGGGGCCA
CTCTGCCCCGAACACGGCCAGGCTCTGAGCTGGTTCTGCGGCTCCGAGCGACGGCCCGTG
TGCGCCGCCTGCGCGGGGTTGGGCGGTCGCTGCCGGGGGCACCGCATCCGCCGGGCGGAG
GAGCGCGCCGAGGAGCTGCGGAACAAGATTGTGGACCAGTGTGAGAGGCTGCAGTTACAG
AGTGCTGCCATCACCAAGTATGTGGCGGACGTCCTGCCGGGGAAGAATCAAAGAGCAGTG
AGCATGGCCAGTGCAGCGAGGGAACTGGTTATCCAGCGGTTGAGTCTGGTGAGGAGTCTT
TGCGAGAGCGAGGAGCAGCGGTTACTGGAACAGGTGCATGGCGAAGAGGAGCGGGCCCAC
CAGAGCATCCTGACACAGCGGGTGCACTGGGCCGAGGCGCTGCAGAAACTTGACACCATC
CGCACTGGCCTGGTGGGCATGCTTACTCACCTGGATGACCTCCAGCTGATTCAGAAGGAG
CAAGAGATTTTCGAGAGGACCGAAGAAGCAGAGGGCATTTTGGATCCCCAGGAGTCGGAA
ATGTTAAACTTTAATGAGAAGTGCACTCGGAGCCCACTACTGACCCAACTCTGGGCAACG
GCGGTTCTTGGGTCTCTCTCAGGCACAGAGGACATACGGATCGATGAGAGGACAGTCAGC
CCCTTCCTGCAATTGTCAGATGATCGAAAGACCCTGACCTTCAGCACCAAGAAGTCAAAG
GCCTGTGCAGATGGCCCGGAGCGCTTCGACCACTGGCCCAATGCCCTGGCTGCCACCTCC
TTCCAGAATGGGCTCCATGCCTGGATGGTGAATGTCCAGAACAGTTGTGCCTATAAGGTG
GGCGTGGCTTCAGGCCACCTGCCCCGCAAGGGTTCTGGCAGTGACTGCCGTCTGGGCCAC
AATGCCTTCTCCTGGGTCTTCTCTCGCTATGATCAGGAGTTTCGTTTCTCACACAATGGG
CAGCACGAGCCCCTGGGGCTGCTGCGGGGCCCAGCCCAGCTGGGTGTAGTGCTGGACTTG
CAGGTTCAGGAGCTGCTCTTCTATGAGCCAGCCTCCGGCATAGTGCTCTGTGCCCATCAT
GTGTCCTTCCCGGGGCCCCTCTTCCCAGTCTTTGCTGTGGCCGATCAGACCATTTCTATC
GTCCGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 402 |
| Molecular Weight
| 44380.8 |
| Theoretical pI
| 6.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>B box and SPRY domain-containing protein
MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE
ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL
CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE
QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS
PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV
GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL
QVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR
|
| External Links |
|---|
| GenBank ID Protein
| 10241474 |
| UniProtKB/Swiss-Prot ID
| Q5W0U4 |
| UniProtKB/Swiss-Prot Entry Name
| BSPRY_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ276691 |
| GeneCard ID
| BSPRY |
| GenAtlas ID
| BSPRY |
| HGNC ID
| HGNC:18232 |
| References |
|---|
| General References
| Not Available |