| Identification |
|---|
| HMDB Protein ID
| CDBP02689 |
| Secondary Accession Numbers
| Not Available |
| Name
| Bombesin receptor subtype-3 |
| Description
| Not Available |
| Synonyms
|
- BRS-3
|
| Gene Name
| BRS3 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system |
| GO Classification
|
| Component |
| integral to membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| Function |
| neuropeptide receptor activity |
| bombesin receptor activity |
| receptor activity |
| molecular transducer activity |
| signal transducer activity |
| peptide receptor activity |
| peptide receptor activity, g-protein coupled |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| BRS3 |
| Gene Sequence
|
>1200 bp
ATGGCTCAAAGGCAGCCTCACTCACCTAATCAGACTTTAATTTCAATCACAAATGACACA
GAATCATCAAGCTCTGTGGTTTCTAACGATAACACAAATAAAGGATGGAGCGGGGACAAC
TCTCCAGGAATAGAAGCATTGTGTGCCATCTATATTACTTATGCTGTGATCATTTCAGTG
GGCATCCTTGGAAATGCTATTCTCATCAAAGTCTTTTTCAAGACCAAATCCATGCAAACA
GTTCCAAATATTTTCATCACCAGCCTGGCTTTTGGAGATCTTTTACTTCTGCTAACTTGT
GTGCCAGTGGATGCAACTCACTACCTTGCAGAAGGATGGCTGTTCGGAAGAATTGGTTGT
AAGGTGCTCTCTTTCATCCGGCTCACTTCTGTTGGTGTGTCAGTGTTCACATTAACAATT
CTCAGCGCTGACAGATACAAGGCAGTTGTGAAGCCACTTGAGCGACAGCCCTCCAATGCC
ATCCTGAAGACTTGTGTAAAAGCTGGCTGCGTCTGGATCGTGTCTATGATATTTGCTCTA
CCTGAGGCTATATTTTCAAATGTATACACTTTTCGAGATCCCAATAAAAATATGACATTT
GAATCATGTACCTCTTATCCTGTCTCTAAGAAGCTCTTGCAAGAAATACATTCTCTGCTG
TGCTTCTTAGTGTTCTACATTATTCCACTCTCTATTATCTCTGTCTACTATTCCTTGATT
GCTAGGACCCTTTACAAAAGCACCCTGAACATACCTACTGAGGAACAAAGCCATGCCCGT
AAGCAGATTGAATCCCGAAAGAGAATTGCCAGAACGGTATTGGTGTTGGTGGCTCTGTTT
GCCCTCTGCTGGTTGCCAAATCACCTCCTGTACCTCTACCATTCATTCACTTCTCAAACC
TATGTAGACCCCTCTGCCATGCATTTCATTTTCACCATTTTCTCTCGGGTTTTGGCTTTC
AGCAATTCTTGCGTAAACCCCTTTGCTCTCTACTGGCTGAGCAAAAGCTTCCAGAAGCAT
TTTAAAGCTCAGTTGTTCTGTTGCAAGGCGGAGCGGCCTGAGCCTCCTGTTGCTGACACC
TCTCTTACCACCCTGGCTGTGATGGGAACGGTCCCGGGCACTGGGAGCATACAGATGTCT
GAAATTAGTGTGACCTCGTTCACTGGGTGTAGTGTGAAGCAGGCAGAGGACAGATTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 399 |
| Molecular Weight
| 44410.4 |
| Theoretical pI
| 8.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["42-63", "83-103", "122-143", "164-184", "221-241", "273-293", "314-333"]
|
| Protein Sequence
|
>Bombesin receptor subtype-3
MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFAL
PEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQT
YVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADT
SLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
|
| External Links |
|---|
| GenBank ID Protein
| 50612574 |
| UniProtKB/Swiss-Prot ID
| P32247 |
| UniProtKB/Swiss-Prot Entry Name
| BRS3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY585193 |
| GeneCard ID
| BRS3 |
| GenAtlas ID
| BRS3 |
| HGNC ID
| HGNC:1113 |
| References |
|---|
| General References
| Not Available |