| Identification |
|---|
| HMDB Protein ID
| CDBP02671 |
| Secondary Accession Numbers
| Not Available |
| Name
| Annexin A8 |
| Description
| Not Available |
| Synonyms
|
- Annexin VIII
- Annexin-8
- VAC-beta
- Vascular anticoagulant-beta
|
| Gene Name
| ANXA8 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium-dependent phospholipid binding |
| calcium ion binding |
| lipid binding |
| phospholipid binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10q11.22 |
| SNPs
| ANXA8 |
| Gene Sequence
|
>984 bp
ATGGCCTGGTGGAAATCCTGGATTGAACAGGAGGGTGTCACAGTGAAGAGCAGCTCCCAC
TTCAACCCAGACCCTGATGCAGAGACCCTCTACAAAGCCATGAAGGGGATCGGGACCAAC
GAGCAGGCTATCATCGATGTGCTCACCAAGAGAAGCAACACGCAGCGGCAGCAGATCGCC
AAGTCCTTCAAGGCTCAGTTCGGCAAGGACCTCACTGAGACCTTGAAGTCTGAGCTCAGT
GGCAAGTTTGAGAGGCTCATTGTGGCCCTTATGTACCCGCCATACAGATACGAAGCCAAG
GAGCTGCATGACGCCATGAAGGGCTTAGGAACCAAGGAGGGTGTCATCATTGAGATCCTG
GCCTCTCGGACCAAGAACCAGCTGCGGGAGATAATGAAGGCGTATGAGGAAGACTATGGG
TCCAGCCTGGAGGAGGACATCCAAGCAGACACAAGTGGCTACCTGGAGAGGATCCTGGTG
TGCCTCCTGCAGGGCAGCAGGGATGATGTGAGCAGCTTTGTGGACCCAGGACTGGCCCTC
CAAGACGCACAGGATCTGTATGCGGCAGGCGAGAAGATTCGTGGGACTGATGAGATGAAA
TTCATCACCATCCTGTGCACGCGCAGTGCCACTCACCTGCTGAGAGTGTTTGAAGAGTAT
GAGAAAATTGCCAACAAGAGCATTGAGGACAGCATCAAGAGTGAGACCCATGGCTCACTG
GAGGAGGCCATGCTCACTGTGGTGAAATGCACCCAAAACCTCCACAGCTACTTTGCAGAG
AGACTCTACTATGCCATGAAGGGAGCAGGGACGCGTGATGGGACCCTGATAAGAAACATC
GTTTCAAGGAGCGAGATTGACTTAAATCTTATCAAATGTCACTTCAAGAAGATGTACGGC
AAGACCCTCAGCAGCATGATCATGGAAGACACCAGCGGTGACTACAAGAACGCCCTGCTG
AGCCTGGTGGGCAGCGACCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 327 |
| Molecular Weight
| 36880.6 |
| Theoretical pI
| 5.51 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Annexin A8
MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIA
KSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEIL
ASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLAL
QDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSL
EEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYG
KTLSSMIMEDTSGDYKNALLSLVGSDP
|
| External Links |
|---|
| GenBank ID Protein
| 55665641 |
| UniProtKB/Swiss-Prot ID
| P13928 |
| UniProtKB/Swiss-Prot Entry Name
| ANXA8_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL591684 |
| GeneCard ID
| ANXA8 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |