| Identification |
|---|
| HMDB Protein ID
| CDBP02665 |
| Secondary Accession Numbers
| Not Available |
| Name
| Annexin A11 |
| Description
| Not Available |
| Synonyms
|
- 56 kDa autoantigen
- Annexin XI
- Annexin-11
- CAP-50
- Calcyclin-associated annexin 50
|
| Gene Name
| ANXA11 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis |
| GO Classification
|
| Function |
| metal ion binding |
| binding |
| calcium-dependent phospholipid binding |
| calcium ion binding |
| lipid binding |
| phospholipid binding |
| ion binding |
| cation binding |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
- Cytoplasm
- Melanosome
- cytoskeleton
- Nucleus envelope
- spindle
- nucleoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10q23 |
| SNPs
| ANXA11 |
| Gene Sequence
|
>1518 bp
ATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGT
GGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGAT
AACGTGGCCACCTATGCGGGGCAGTTCAACCAGGACTATCTCTCGGGAATGGCGGCCAAC
ATGTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCT
GGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTT
CCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCTCCAGGATGCCCTCATAT
CCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCC
CCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTC
CCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGGGACTGTCACC
CCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTT
GACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATGAG
CAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGCGGCAGCAGATCCTACTT
TCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGA
AACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAG
ATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCGCT
TCCCGCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAG
ACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCT
CTCTCTCAGGGAAACCGTGATGAAAGCACAAACGTGGACATGTCACTCGCCCAGAGAGAT
GCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAACAGACGAGTCCAAGTTCAAT
GCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGAGTACCAGAGA
ATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGTCCGGGGACCTGGAGGAG
GGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTC
AACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCT
CGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGCGGATGTACGGCAAGTCG
CTGTACCACGACATCTCGGGAGATACTTCAGGGGATTACCGGAAGATTCTGCTGAAGATC
TGTGGTGGCAATGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 505 |
| Molecular Weight
| 54389.3 |
| Theoretical pI
| 7.77 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Annexin A11
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
LYHDISGDTSGDYRKILLKICGGND
|
| External Links |
|---|
| GenBank ID Protein
| 8671171 |
| UniProtKB/Swiss-Prot ID
| P50995 |
| UniProtKB/Swiss-Prot Entry Name
| ANX11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ278463 |
| GeneCard ID
| ANXA11 |
| GenAtlas ID
| ANXA11 |
| HGNC ID
| HGNC:535 |
| References |
|---|
| General References
| Not Available |