| Identification |
|---|
| HMDB Protein ID
| CDBP02662 |
| Secondary Accession Numbers
| Not Available |
| Name
| Anoctamin-9 |
| Description
| Not Available |
| Synonyms
|
- Transmembrane protein 16J
- Tumor protein p53-inducible protein 5
- p53-induced gene 5 protein
|
| Gene Name
| ANO9 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chloride channel activity |
| Specific Function
| May act as a calcium-activated chloride channel |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.5 |
| SNPs
| ANO9 |
| Gene Sequence
|
>2349 bp
ATGCAGGGCGAAGAGAGCCTCCGGATCCTGGTGGAGCCCGAAGGGGACAGCTTCCCGCTG
ATGGAGATCAGCACCTGTGAGACCGAGGCCTCCGAGCAGTGGGACTATGTCCTCGTGGCC
CAACGTCACACCCAGAGAGACCCCCGGCAGGCGCGGCAGCAACAGTTCCTGGAGGAGCTC
AGGAGAAAGGGCTTCCACATTAAGGTGATCCGGGACCAGAAACAGGTCTTCTTTGGGATC
CGTGCTGACAACAGTGTCTTTGGCCTGTACCGCACTCTCCTCCTGGAGCCTGAGGGGCCT
GCCCCCCACGCCGAGCTGGCCGCGCCGACCACCATCCCGGTCACCACGAGTCTCAGAATC
CGAATCGTGAACTTCGTTGTCATGAACAACAAGACCTCGGCTGGTGAGACCTTCGAGGAT
CTGATGAAGGACGGGGTCTTTGAGGCCAGGTTCCCCCTGCACAAGGGGGAGGGACGCCTG
AAGAAGACGTGGGCGCGGTGGAGACACATGTTCCGGGAGCAGCCAGTTGATGAAATCAGG
AACTACTTTGGGGAAAAGGTGGCCCTGTACTTCGTCTGGCTGGGCTGGTACACCTACATG
CTGGTGCCGGCCGCCCTGACGGGCCTCTTAGTCTTTCTGAGCGGATTCTCGCTGTTTGAG
GCCAGCCAGATCAGCAAGGAGATCTGTGAGGCCCACGACATCCTCATGTGTCCCCTCGGC
GACCACAGCCGCAGGTACCAGCGGCTCTCGGAAACCTGCACTTTTGCCAAGCTCACCCAC
CTCTTTGACAATGATGGCACGGTGGTGTTCGCCATCTTCATGGCTCTCTGGGCCACGGTG
TTCCTGGAGATCTGGAAGCGGCAGCGCGCCCGCGTGGTCCTGCACTGGGACCTGTACGTG
TGGGACGAGGAACAGGAGGAAATGGCACTTCAGCTCATTAACTGCCCCGACTACAAGCTC
CGGCCATACCAGCACTCCTACCTACGCAGCACCGTCATCCTCGTCCTGACCCTGCTCATG
ATCTGCCTCATGATCGGCATGGCCCACGTCCTGGTGGTCTACCGCGTCCTGGCCTCCGCG
CTCTTCAGCAGCTCGGCCGTGCCCTTCCTGGAGGAGCAGGTGACCACGGCCGTGGTGGTG
ACCGGGGCTCTGGTGCACTATGTGACCATCATCATCATGACCAAGATCAACAGGTGCGTG
GCCCTGAAGCTTTGTGACTTCGAGATGCCCAGGACCTTCTCGGAGCGAGAGAGCAGGTTC
ACCATCCGCTTCTTCACACTGCAGTTCTTCACCCATTTCTCGTCTCTCATCTACATCGCC
TTCATCCTGGGCAGGATCAACGGCCACCCCGGGAAGTCCACGCGCCTGGCGGGCTTGTGG
AAGCTGGAAGAGTGCCACGCCAGCGGCTGCATGATGGACCTCTTCGTGCAGATGGCCATC
ATCATGGGCCTGAAGCAGACGCTCAGCAACTGCGTCGAGTACCTGGTCCCGTGGGTGACC
CACAAGTGCCGCTCTCTGCGGGCCTCCGAGTCCGGGCACCTGCCCCGGGACCCCGAGCTC
AGGGACTGGCGGCGCAACTACCTTCTGAACCCGGTCAACACCTTCAGCCTGTTCGACGAG
TTCATGGAGATGATGATCCAGTACGGCTTCACCACCATCTTCGTGGCCGCCTTCCCGCTG
GCGCCGCTGCTCGCGCTCTTCAGCAACCTCGTGGAGATCCGCCTGGACGCCATCAAGATG
GTCTGGTTGCAGCGGCGCCTGGTGCCGCGCAAGGCCAAGGACATCGGGACCTGGCTGCAG
GTGCTGGAGACCATCGGTGTGCTGGCGGTCATTGCCAATGGGATGGTCATTGCCTTCACA
TCTGAGTTCATCCCCCGAGTGGTCTACAAGTACCGCTATAGCCCATGCCTGAAAGAAGGC
AACTCTACTGTCGACTGCCTCAAGGGCTACGTCAACCACAGCCTGTCCGTCTTCCACACC
AAGGACTTCCAGGACCCTGATGGGATTGAGGGCTCAGAAAACGTGACTCTGTGCAGATAC
AGGGACTACCGCAATCCCCCCGATTACAACTTCTCCGAGCAGTTCTGGTTCCTCCTGGCC
ATCCGCCTGGCCTTCGTCATCCTCTTTGAGCACGTGGCCTTGTGCATCAAGCTCATCGCC
GCCTGGTTCGTGCCCGACATCCCTCAGTCGGTGAAGAACAAGGTTCTGGAGGTGAAGTAC
CAGAGGCTGCGTGAGAAGATGTGGCATGGAAGGCAGAGGCTGGGTGGGGTGGGGGCAGGC
TCTCGGCCCCCAATGCCTGCCCATCCCACCCCAGCATCCATCTTCAGTGCCAGGAGCACA
GACGTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 782 |
| Molecular Weight
| 90366.5 |
| Theoretical pI
| 8.24 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["199-219", "265-285", "332-352", "374-394", "424-444", "553-573", "605-625", "704-724"]
|
| Protein Sequence
|
>Anoctamin-9
MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQQFLEEL
RRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTFLLEPEGPAPHAELAAPTTIPVTTSLRI
RIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGRLKKTWARWRHMFREQPVDEIR
NYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLG
DHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYV
WDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASA
LFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRF
TIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAI
IMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDE
FMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQ
VLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHT
KDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIA
AWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARST
DV
|
| External Links |
|---|
| GenBank ID Protein
| 145611446 |
| UniProtKB/Swiss-Prot ID
| A1A5B4 |
| UniProtKB/Swiss-Prot Entry Name
| ANO9_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001012302.2 |
| GeneCard ID
| ANO9 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |