| Identification |
|---|
| HMDB Protein ID
| CDBP02653 |
| Secondary Accession Numbers
| Not Available |
| Name
| Anoctamin-10 |
| Description
| Not Available |
| Synonyms
|
- Transmembrane protein 16K
|
| Gene Name
| ANO10 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chloride channel activity |
| Specific Function
| May act as a calcium-activated chloride channel |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p22.1 |
| SNPs
| ANO10 |
| Gene Sequence
|
>1983 bp
ATGAAAGTGACCTTATCAGCTTTGGATACTTCTGAGAGTTCTTTCACACCTTTGGTGGTC
ATAGAACTTGCTCAGGATGTCAAAGAAGAAACCAAAGAATGGCTGAAAAACAGAATTATA
GCTAAAAAAAAAGATGGAGGTGCCCAGTTGTTGTTTAGACCATTGTTAAATAAATATGAA
CAAGAAACACTAGAAAATCAGAACTTATATCTTGTTGGTGCCTCCAAGATTAGAATGTTA
CTAGGGGCAGAAGCAGTGGGATTGGTAAAAGAGTGCAATGATAACACCATGAGAGCCTTC
ACATACAGAACCAGACAGAACTTCAAAGGTTTTGATGATAACAATGATGATTTCCTGACA
ATGGCAGAATGTCAATTCATTATCAAACATGAACTTGAAAATCTTAGAGCTAAAGATGAA
AAAATGATCCCTGGTTACCCTCAGGCAAAGTTGTATCCAGGAAAATCATTGTTGAGAAGA
TTGCTCACGTCTGGCATCGTGATTCAGGTGTTTCCACTGCATGACAGTGAAGCCCTGAAG
AAGCTTGAGGACACCTGGTACACTCGGTTTGCTTTGAAGTATCAGCCCATAGACAGTATT
CGTGGCTACTTTGGGGAAACAATTGCTCTGTACTTTGGATTTTTGGAGTATTTCACTTTT
GCATTAATCCCCATGGCTGTCATTGGGTTACCTTACTACTTGTTTGTGTGGGAAGACTAT
GACAAGTACGTGATCTTTGCCTCGTTCAACCTCATCTGGTCCACGGTGATTCTGGAACTG
TGGAAGCGTGGCTGTGCCAACATGACCTACAGGTGGGGGACACTGCTCATGAAGAGAAAG
TTTGAGGAGCCCCGGCCAGGATTTCATGGTGTCTTGGGTATCAATTCCATCACTGGGAAG
GAGGAGCCTCTGTACCCCAGCTACAAGAGACAGTTGCGCATTTACCTGGTCTCCCTGCCA
TTCGTGTGCCTCTGCCTCTATTTCTCACTGTATGTCATGATGATTTACTTCGACATGGAG
GTTTGGGCCTTGGGTCTACATGAGAACAGCGGGTCTGAGTGGACCAGTGTCCTGTTGTAT
GTGCCCAGCATCATCTATGCCATTGTGATTGAGATCATGAATCGTCTCTATCGATATGCT
GCCGAGTTTTTAACTTCATGGGAGAATCACAGATTGGAATCTGCCTATCAGAACCATCTA
ATTCTGAAAGTTTTAGTGTTCAACTTCCTCAATTGCTTTGCCTCACTCTTCTATATTGCC
TTTGTCTTGAAAGATATGAAGCTTTTGCGCCAGAGCTTGGCCACTCTCCTAATTACCTCC
CAGATCCTCAACCAAATTATGGAATCTTTTCTTCCTTATTGGCTCCAAAGGAAGCATGGT
GTGCGGGTGAAGAGGAAGGTGCAGGCTTTAAAGGCAGACATTGATGCTACATTATATGAA
CAAGTCATCCTGGAAAAAGAAATGGGAACTTATTTGGGCACCTTTGATGATTACTTGGAG
TTATTCCTGCAGTTTGGTTATGTGAGCCTTTTCTCCTGTGTTTACCCATTAGCAGCTGCC
TTTGCTGTGTTAAATAACTTCACTGAAGTAAATTCAGATGCCTTAAAAATGTGCAGGGTC
TTCAAACGTCCATTCTCAGAACCTTCAGCCAATATTGGTGTGTGGCAGTTGGCTTTTGAA
ACGATGAGTGTTATATCTGTGGTCACTAACTGTGCGCTGATTGGAATGTCACCACAAGTG
AATGCAGTCTTTCCAGAATCAAAAGCAGACCTCATTTTGATTGTAGTAGCAGTGGAGCAC
GCACTCCTGGCTTTAAAGTTTATACTTGCATTTGCCATACCTGATAAGCCACGGCATATC
CAGATGAAACTAGCCAGACTGGAATTTGAGTCTTTGGAGGCACTCAAGCAGCAGCAAATG
AAGCTCGTGACCGAGAACCTGAAGGAGGAACCAATGGAAAGCGGGAAGGAGAAGGCAACC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 660 |
| Molecular Weight
| 76328.6 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["208-228", "241-261", "317-337", "353-373", "401-421", "501-521", "554-574", "591-611"]
|
| Protein Sequence
|
>Anoctamin-10
MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYE
QETLENQNLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLT
MAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALK
KLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWEDY
DKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLGINSITGK
EEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLY
VPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIA
FVLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRKVQALKADIDATLYE
QVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRV
FKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPESKADLILIVVAVEH
ALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT
|
| External Links |
|---|
| GenBank ID Protein
| 94536803 |
| UniProtKB/Swiss-Prot ID
| Q9NW15 |
| UniProtKB/Swiss-Prot Entry Name
| ANO10_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018075.3 |
| GeneCard ID
| ANO10 |
| GenAtlas ID
| ANO10 |
| HGNC ID
| HGNC:25519 |
| References |
|---|
| General References
| Not Available |