Showing Protein Alkaline ceramidase 3 (CDBP02631)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP02631
Secondary Accession Numbers Not Available
Name Alkaline ceramidase 3
Description Not Available
Synonyms
  1. AlkCDase 3
  2. Alkaline CDase 3
  3. Alkaline dihydroceramidase SB89
  4. Alkaline phytoceramidase
  5. aPHC
Gene Name ACER3
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Specific Function Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
GO Classification
Biological Process
sphingosine biosynthetic process
ceramide metabolic process
positive regulation of cell proliferation
phytosphingosine biosynthetic process
phospholipid metabolic process
Cellular Component
integral to endoplasmic reticulum membrane
integral to Golgi membrane
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Function
phytoceramidase activity
Process
metabolic process
ceramide metabolic process
sphingolipid metabolic process
membrane lipid metabolic process
primary metabolic process
lipid metabolic process
cellular lipid metabolic process
sphingoid metabolic process
Cellular Location
  1. Golgi apparatus membrane
  2. Endoplasmic reticulum membrane
  3. Multi-pass membrane protein
  4. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs ACER3
Gene Sequence 
>804 bp
ATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGG
TGCGAGGAGAACTACTCCGTGACCTGGTACATCGCCGAGTTCTGGAATACAGTGAGTAAC
CTGATCATGATTATACCTCCAATGTTCGGTGCAATTCAGAGTGTTAGAGACGGTCTGGAA
AAACGGTACATTGCTTCTTATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTC
CACATGACTCTGAAATATGAAATGCAGCTATTGGATGAACTCCCAATGATATACAGCTGT
TGCATATTTGTGTACTGCATGTTTGAATGTTTCAAGATCAAGAACTCAGTAAACTACCAT
CTGCTTTTTACCTTAGTTCTATTCAGTTTAATAGTAACCACAGTTTACCTTAAGGTAAAA
GAGCCAATATTCCATCAGGTCATGTATGGAATGTTGGTCTTTACATTAGTACTTCGATCT
ATTTATATTGTTACATGGGTTTATCCATGGCTTAGAGGACTGGGTTATACATCATTGGGT
ATATTTTTATTGGGATTTTTATTTTGGAATATAGATAACATATTTTGTGAGTCACTGAGG
AACTTTCGAAAGAAGGTACCACCTATCATAGGTATTACCACACAATTTCATGCATGGTGG
CATATTTTAACTGGCCTTGGTTCCTATCTTCACATCCTTTTCAGTTTGTATACAAGAACA
CTTTACCTGAGATATAGGCCAAAAGTGAAGTTTCTCTTTGGAATCTGGCCAGTGATCCTG
TTTGAGCCTCTCAGGAAGCATTGA
Protein Properties
Number of Residues 267
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Alkaline ceramidase 3
MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFWNTVSNLIMIIPPMFGAVQSVRDGLE
KRYIASYLALTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKIKNSVNYH
LLFTLVLFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLRGLGYTSLG
IFLLGFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYTRT
LYLRYRPKVKFLFGIWPVILFEPLRKH
GenBank ID Protein 14669436
UniProtKB/Swiss-Prot ID Q9NUN7
UniProtKB/Swiss-Prot Entry Name ACER3_HUMAN
PDB IDs Not Available
GenBank Gene ID AF214454
GeneCard ID ACER3
GenAtlas ID ACER3
HGNC ID HGNC:16066
References
General References Not Available