Showing Protein Thioredoxin domain-containing protein 12 (CDBP02610)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02610
Secondary Accession Numbers Not Available
Name Thioredoxin domain-containing protein 12
Description Not Available
Synonyms
  1. ER protein 18
  2. ER protein 19
  3. ERp18
  4. ERp19
  5. Endoplasmic reticulum resident protein 18
  6. Endoplasmic reticulum resident protein 19
  7. Thioredoxin-like protein p19
  8. hTLP19
Gene Name TXNDC12
Protein Type Enzyme
Biological Properties
General Function Involved in cell redox homeostasis
Specific Function Possesses significant protein thiol-disulfide oxidase activity.
GO Classification
Biological Process
cell redox homeostasis
Cellular Component
endoplasmic reticulum lumen
Molecular Function
protein-disulfide reductase (glutathione) activity
Process
cellular process
cellular homeostasis
cell redox homeostasis
Cellular Location
  1. Endoplasmic reticulum lumen
Pathways
Gene Properties
Chromosome Location 1
Locus 1p32.3
SNPs TXNDC12
Gene Sequence 
>519 bp
ATGGAGACGCGGCCTCGTCTCGGGGCCACCTGTTTGCTGGGCTTCAGTTTCCTGCTCCTC
GTCATCTCTTCTGATGGACATAATGGGCTTGGAAAGGGTTTTGGAGATCATATTCATTGG
AGGACACTGGAAGATGGGAAGAAAGAAGCAGCTGCCAGTGGACTGCCCCTGATGGTGATT
ATTCATAAATCCTGGTGTGGAGCTTGCAAAGCTCTAAAGCCCAAATTTGCAGAATCTACG
GAAATTTCAGAACTCTCCCATAATTTTGTTATGGTAAATCTTGAGGATGAAGAGGAACCC
AAAGATGAAGATTTCAGCCCTGACGGGGGTTATATTCCACGAATCCTTTTTCTGGATCCC
AGTGGCAAGGTGCATCCTGAAATCATCAATGAGAATGGAAACCCCAGCTACAAGTATTTT
TATGTCAGTGCCGAGCAAGTTGTTCAGGGGATGAAGGAAGCTCAGGAAAGGCTGACGGGT
GATGCCTTCAGAAAGAAACATCTTGAAGATGAATTGTAA
Protein Properties
Number of Residues 172
Molecular Weight 19205.615
Theoretical pI 5.405
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Thioredoxin domain-containing protein 12
METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVI
IHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDP
SGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
GenBank ID Protein 4406577
UniProtKB/Swiss-Prot ID O95881
UniProtKB/Swiss-Prot Entry Name TXD12_HUMAN
PDB IDs
GenBank Gene ID AF131758
GeneCard ID TXNDC12
GenAtlas ID TXNDC12
HGNC ID HGNC:24626
References
General References Not Available