| Identification |
|---|
| HMDB Protein ID
| CDBP02604 |
| Secondary Accession Numbers
| Not Available |
| Name
| Enoyl-CoA delta isomerase 2, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- D3,D2-enoyl-CoA isomerase
- DBI-related protein 1
- DRS-1
- Delta(3),delta(2)-enoyl-CoA isomerase
- Diazepam-binding inhibitor-related protein 1
- Dodecenoyl-CoA isomerase
- Hepatocellular carcinoma-associated antigen 88
- Renal carcinoma antigen NY-REN-1
- pECI
- Peroxisomal 3,2-trans-enoyl-CoA isomerase
|
| Gene Name
| ECI2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acyl-CoA binding |
| Specific Function
| Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity).
|
| GO Classification
|
| Biological Process |
| fatty acid catabolic process |
| Cellular Component |
| peroxisomal matrix |
| mitochondrion |
| Function |
| binding |
| catalytic activity |
| fatty acid binding |
| acyl-coa binding |
| lipid binding |
| Molecular Function |
| fatty-acyl-CoA binding |
| dodecenoyl-CoA delta-isomerase activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Isoform 2:Peroxisome matrix
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Peroxisome | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| 6p24.3 |
| SNPs
| PECI |
| Gene Sequence
|
>1185 bp
ATGGCGATGGCGTACTTGGCTTGGAGACTGGCGCGGCGTTCGTGTCCGAGTTCTCTGCAG
GTCACTAGTTTCCCGGTAGTTCAGCTGCACATGAATAGAACAGCAATGAGAGCCAGTCAG
AAGGACTTTGAAAATTCAATGAATCAAGTGAAACTCTTGAAAAAGGATCCAGGAAACGAA
GTGAAGCTAAAACTCTACGCGCTATATAAGCAGGCCACTGAAGGACCTTGTAACATGCCC
AAACCAGGTGTATTTGACTTGATCAACAAGGCCAAATGGGACGCATGGAATGCCCTTGGC
AGCCTGCCCAAGGAAGCTGCCAGGCAGAACTATGTGGATTTGGTGTCCAGTTTGAGTCCT
TCATTGGAATCCTCTAGTCAGGTGGAGCCTGGAACAGACAGGAAATCAACTGGGTTTGAA
ACTCTGGTGGTGACCTCCGAAGATGGCATCACAAAGATCATGTTCAACCGGCCCAAAAAG
AAAAATGCCATAAACACTGAGATGTATCATGAAATTATGCGTGCACTTAAAGCTGCCAGC
AAGGATGACTCAATCATCACTGTTTTAACAGGAAATGGTGACTATTACAGTAGTGGGAAT
GATCTGACTAACTTCACTGATATTCCCCCTGGTGGAGTAGAGGAGAAAGCTAAAAATAAT
GCCGTTTTACTGAGGGAATTTGTGGGCTGTTTTATAGATTTTCCTAAGCCTCTGATTGCA
GTGGTCAATGGTCCAGCTGTGGGCATCTCCGTCACCCTCCTTGGGCTATTCGATGCCGTG
TATGCATCTGACAGGGCAACATTTCATACACCATTTAGTCACCTAGGCCAAAGTCCGGAA
GGATGCTCCTCTTACACTTTTCCGAAGATAATGAGCCCAGCCAAGGCAACAGAGATGCTT
ATTTTTGGAAAGAAGTTAACAGCGGGAGAGGCATGTGCTCAAGGACTTGTTACTGAAGTT
TTCCCTGATAGCACTTTTCAGAAAGAAGTCTGGACCAGGCTGAAGGCATTTGCAAAGCTT
CCCCCAAATGCCTTGAGAATTTCAAAAGAGGTAATCAGGAAAAGAGAGAGAGAAAAACTA
CACGCTGTTAATGCTGAAGAATGCAATGTCCTTCAGGGAAGATGGCTATCAGATGAATGC
ACAAATGCTGTGGTGAACTTCTTATCCAGAAAATCAAAACTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 394 |
| Molecular Weight
| 40182.735 |
| Theoretical pI
| 8.767 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Peroxisomal 3,2-trans-enoyl-CoA isomerase
MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNE
VKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVDLVSSLSP
SLESSSQVEPGTDRKSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAAS
KDDSIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVGCFIDFPKPLIA
VVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEML
IFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRKREREKL
HAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL
|
| External Links |
|---|
| GenBank ID Protein
| 260274832 |
| UniProtKB/Swiss-Prot ID
| O75521 |
| UniProtKB/Swiss-Prot Entry Name
| PECI_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_206836.2 |
| GeneCard ID
| PECI |
| GenAtlas ID
| PECI |
| HGNC ID
| HGNC:14601 |
| References |
|---|
| General References
| Not Available |