| Identification |
|---|
| HMDB Protein ID
| CDBP02590 |
| Secondary Accession Numbers
| Not Available |
| Name
| Glycine N-acyltransferase-like protein 2 |
| Description
| Not Available |
| Synonyms
|
- Acyl-CoA:glycine N-acyltransferase-like protein 2
|
| Gene Name
| GLYATL2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glycine N-acyltransferase activity |
| Specific Function
| Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine.
|
| GO Classification
|
| Cellular Component |
| endoplasmic reticulum |
| mitochondrion |
| Component |
| mitochondrion |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| glycine n-acyltransferase activity |
| catalytic activity |
| transferase activity |
| transferase activity, transferring acyl groups |
| transferase activity, transferring acyl groups other than amino-acyl groups |
| acyltransferase activity |
| n-acyltransferase activity |
| Molecular Function |
| glycine N-acyltransferase activity |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| 11q12.1 |
| SNPs
| GLYATL2 |
| Gene Sequence
|
>885 bp
ATGCTTGTGCTTCATAACTCTCAGAAGCTGCAGATTCTGTATAAATCCTTAGAAAAGAGC
ATCCCTGAATCCATAAAGGTATATGGCGCCATTTTCAACATAAAAGATAAAAACCCTTTC
AACATGGAGGTGCTGGTAGATGCCTGGCCAGATTACCAGATCGTCATTACCCGGCCTCAG
AAACAGGAGATGAAAGATGACCAGGATCATTATACCAACACTTACCACATCTTCACCAAA
GCTCCTGACAAATTAGAGGAAGTCCTGTCATACTCCAATGTAATCAGCTGGGAGCAAACT
TTGCAGATCCAAGGTTGCCAAGAGGGCTTGGATGAAGCAATAAGAAAGGTTGCAACTTCA
AAATCAGTGCAGGTAGATTACATGAAAACCATCCTCTTTATACCGGAATTACCAAAGAAA
CACAAGACCTCAAGTAATGACAAGATGGAGTTATTTGAAGTGGATGATGATAACAAGAAA
GGAAACTTTTCAAACATGTTCTTAGATGCTTCACATGCAGGTCTTGTGAATGAACACTGG
GCCTTTGGGAAAAATGAGAGGAGCTTGAAATATATTGAACGCTGCCTCCAGGATTTTCTA
GGATTTGGCGTGCTGGGTCCAGAGGGCCAGCTTGTCTCTTGGATTGTGATGGAACGGTCC
TGTGAGTTGAGAATGGGTTATACTGTCCCCAAATACAGACACCAAGGCAACATGTTGCAA
ATTGGTTACCATCTTGAAAAGTATCTTTCTCAGAAAGAAATCCCATTTTATTTCCATGTG
GCAGATAATAATGAGAAAAGCCTACAGGCACTGAACAATTTGGGGTTTAAGATTTGTCCC
TGTGGCTGGCATCAGTGGAAATGCACCCCCAAGAAATGTTGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 294 |
| Molecular Weight
| 34277.055 |
| Theoretical pI
| 6.681 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glycine N-acyltransferase-like protein 2
MLVLHNSQKLQILYKSLEKSIPESIKVYGAIFNIKDKNPFNMEVLVDAWPDYQIVITRPQ
KQEMKDDQDHYTNTYHIFTKAPDKLEEVLSYSNVISWEQTLQIQGCQEGLDEAIRKVATS
KSVQVDYMKTILFIPELPKKHKTSSNDKMELFEVDDDNKEGNFSNMFLDASHAGLVNEHW
AFGKNERSLKYIERCLQDFLGFGVLGPEGQLVSWIVMEQSCELRMGYTVPKYRHQGNMLQ
IGYHLEKYLSQKEIPFYFHVADNNEKSLQALNNLGFKICPCGWHQWKCTPKKYC
|
| External Links |
|---|
| GenBank ID Protein
| 29243559 |
| UniProtKB/Swiss-Prot ID
| Q8WU03 |
| UniProtKB/Swiss-Prot Entry Name
| GLYL2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF426250 |
| GeneCard ID
| GLYATL2 |
| GenAtlas ID
| GLYATL2 |
| HGNC ID
| HGNC:24178 |
| References |
|---|
| General References
| Not Available |