Cannabis Compound Database: Showing Protein Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (CDBP02585)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP02585

Secondary Accession Numbers

Not Available

Name

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

Description

Not Available

Synonyms

Lipid phosphatase TPIP
TPTE and PTEN homologous inositol lipid phosphatase

Gene Name

TPTE2

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein tyrosine/serine/threonine phosphatase activity

Specific Function

Not Available

GO Classification

Biological Process
small molecule metabolic process
phosphatidylinositol biosynthetic process
peptidyl-tyrosine dephosphorylation
Cellular Component
endoplasmic reticulum membrane
integral to membrane
Golgi membrane
Component
membrane
cell part
Function
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
protein tyrosine/serine/threonine phosphatase activity
transporter activity
ion channel activity
Molecular Function
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
ion channel activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
Process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation
protein amino acid dephosphorylation
metabolic process
establishment of localization
transport
cellular metabolic process
transmembrane transport
ion transport

Cellular Location

Isoform 4:Cytoplasm

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

13q12.11

SNPs

TPTE2

Gene Sequence

>1569 bp
ATGAATGAAAGTCCACAGACAAACGAATTTAAAGGAACAACCGAGGAGGCACCTGCGAAA
GAAAGCCCACACACAAGTGAATTTAAAGGAGCAGCCCTGGTGTCACCTATCAGTAAAAGT
ATGTTAGAACGACTTTCCAAGTTTGAAGTTGAAGATGCTGAAAATGTTGCTTCATATGAC
AGCAAGATTAAGAAAATTGTGCATTCAATTGTATCATCCTTTGCATTTGGAATATTTGGA
GTTTTCCTGGTCTTACTGGATGTCACTCTCCTCCTTGCCGACCTAATTTTCACTGACAGC
AAACTTTATATTCCTTTGGAGTATCGTTCTATTTCTCTAGCTATTGGCTTATTTTTTCTC
ATGGATGTTCTTCTTCGAGTATTTGTAGAAGGGAGACAGCAGTATTTTTCTGACTTATTT
AACATTTTAGATACTGCCATTATTGTGATTCCTCTGCTGGTTGATGTCATTTACATTTTT
TTTGACATTAAGTTGCTTAGGAATATTCCCAGATGGACACATTTAGTTCGACTTCTACGA
CTTATTATTCTGATAAGAATTTTTCATCTGCTTCATCAAAAAAGACAACTTGAAAAGCTG
ATGAGAAGGCTGGTTTCAGAAAACAAAAGGCGATACACAAGGGATGGATTTGACCTAGAC
CTCACTTACGTTACAGAACGTATTATTGCTATGTCATTTCCATCTTCTGGAAGGCAGTCT
TTCTATAGAAATCCAATTGAGGAAGTTGTGCGGTTTCTAGATAAGAAACATCGAAACCAC
TATCGAGTCTACAATCTATGCAGTGAAAGAGCTTATGATCCTAAGCACTTCCATAATAGG
GTCAGTAGAATCATGATTGATGATCATAATGTCCCCACTCTACATGAGATGGTGGTTTTC
ACCAAGGAAGTAAATGAGTGGATGGCTCAAGATCTTGAAAACATCGTAGCGATTCACTGT
AAAGGAGGCAAAGGAAGAACCGGGACTATGGTTTGTGCCCTCCTTATTGCCTCCGAAATA
TTTTTAACTGCCGAGGAAAGCCTATATTATTTTGGAGAAAGGCGAACCAATAAAACCCAC
AGCAATAAATTTCAGGGAGTAGAAACTCCTTCTCAGAATAGATATGTTGGATATTTTGCA
CAAGTGAAACATCTCTACAACTGGAATCTCCCTCCAAGACGGATACTCTTTATAAAAAGA
TTCATTATTTATTCGATTCGTGGTGATGTATGTGATCTAAAAGTCCAAGTAGTAATGGAG
AAAAAGGTTGTCTTTTCCAGTACTTCATTAGGAAATTGTTCGATATTGCATGACATTGAA
ACAGACAAAATATTAATTAATGTATATGACGGTCCACCTCTGTATGATGATGTGAAAGTG
CAGTTTTTCTCTTCGAATCTTCCTAAATACTATGACAATTGTCCATTTTTCTTCTGGTTC
AACACGTCTTTTATTCAAAATAACAGGCTTTGTCTACCAAGAAATGAATTGGATAATCCA
CATAAACAAAAAGCATGGAAAATTTATCCACCAGAATTTGCTGTGGAGATACTTTTTGGC
GAGAAATGA

Protein Properties

Number of Residues

522

Molecular Weight

48385.14

Theoretical pI

8.674

Pfam Domain Function

DSPc (PF00782 )
Ion_trans (PF00520 )
PTEN_C2 (PF10409 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2
MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD
SKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL
MDVLLRVFVEGRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIPRWTHLVRLLR
LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF
TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH
SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME
KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF
NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK

External Links

GenBank ID Protein

213972591

UniProtKB/Swiss-Prot ID

Q6XPS3

UniProtKB/Swiss-Prot Entry Name

TPTE2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_199254.2

GeneCard ID