| Identification |
|---|
| HMDB Protein ID
| CDBP02576 |
| Secondary Accession Numbers
| Not Available |
| Name
| Membrane-associated phosphatidylinositol transfer protein 2 |
| Description
| Not Available |
| Synonyms
|
- NIR-3
- PITPnm 2
- Phosphatidylinositol transfer protein, membrane-associated 2
- Pyk2 N-terminal domain-interacting receptor 3
|
| Gene Name
| PITPNM2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| Process |
| establishment of localization |
| transport |
|
| Cellular Location
|
- Endomembrane system
- Peripheral membrane protein (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12q24.31 |
| SNPs
| PITPNM2 |
| Gene Sequence
|
>4050 bp
ATGATTATAAAGGAATATCGGATTCCTCTGCCAATGACCGTGGAGGAGTACCGCATCGCC
CAGCTGTACATGATACAGAAGAAGAGCCGTAACGAGACATATGGCGAAGGCAGCGGCGTG
GAGATCCTGGAGAACCGGCCGTACACAGATGGCCCAGGCGGCTCTGGGCAGTACACACAC
AAGGTGTATCATGTGGGCATGCACATTCCCAGCTGGTTCCGCTCCATCCTGCCCAAGGCA
GCCCTGCGGGTGGTGGAGGAGTCTTGGAATGCCTACCCCTACACCCGAACCAGGTTCACC
TGTCCTTTCGTGGAGAAATTCTCCATCGACATTGAAACCTTTTATAAAACTGATGCTGGA
GAAAACCCCGACGTGTTCAACCTCTCTCCTGTGGAAAAGAACCAGCTGACAATCGACTTC
ATCGACATTGTCAAAGACCCTGTGCCCCACAACGAGTATAAGACAGAAGAGGACCCCAAG
CTGTTCCAGTCAACCAAGACCCAGCGGGGGCCCCTGTCCGAGAACTGGATCGAGGAGTAC
AAGAAGCAGGTCTTCCCCATCATGTGCGCATACAAGCTCTGCAAGGTGGAGTTCCGCTAC
TGGGGCATGCAGTCCAAGATCGAGAGGTTCATCCACGACACCGGACTACGGAGGGTGATG
GTGCGGGCTCACCGGCAGGCCTGGTGCTGGCAGGACGAGTGGTATGGGCTGAGCATGGAG
AACATCCGGGAGCTGGAGAAGGAGGCACAGCTCATGCTTTCCCGTAAGATGGCCCAGTTC
AATGAGGATGGTGAGGAGGCCACTGAGCTCGTCAAGCACGAAGCCGTCTCGGACCAGACC
TCTGGGGAGCCCCCGGAGCCCAGCAGCAGCAATGGGGAGCCCCTAGTGGGGCGCGGCCTC
AAGAAACAGTGGTCCACATCCTCCAAGTCGTCTCGGTCGTCCAAGCGGGGAGCGAGTCCT
TCCCGCCACAGCATCTCAGAGTGGAGGATGCAGAGTATTGCCAGGGACTCGGATGAGAGC
TCAGATGATGAGTTCTTCGATGCGCACGAGGACCTGTCCGACACAGAGGAAATGTTCCCC
AAGGACATCACCAAGTGGAGCTCCAATGACCTCATGGACAAGATCGAGAGCCCAGAGCCG
GAAGACACACAAGATGGTCTGTACCGCCAGGGTGCCCCTGAGTTCAGGGTGGCCTCCAGT
GTGGAGCAGCTGAACATCATAGAGGACGAGGTTAGCCAGCCGCTGGCTGCACCGCCCTCC
AAGATCCACGTGCTGCTACTGGTGCTGCACGGAGGCACCATCCTGGACACAGGCGCCGGG
GACCCCAGCTCCAAGAAGGGCGATGCTAACACCATCGCCAACGTGTTCGACACCGTCATG
CGCGTGCACTACCCCAGCGCCCTGGGCCGCCTTGCCATCCGCCTGGTGCCCTGCCCGCCC
GTCTGCTCTGACGCCTTTGCCCTGGTCTCCAACCTCAGCCCCTACAGCCATGACGAAGGC
TGTCTGTCCAGCAGTCAGGACCACATTCCCCTGGCTGCCCTCCCCCTGCTGGCCACCTCC
TCCCCCCAGTACCAGGAGGCAGTTGCCACAGTGATTCAGCGAGCCAACCTTGCCTATGGG
GACTTCATCAAGTCCCAGGAGGGCATGACCTTCAATGGGCAGGTCTGCCTGATTGGGGAC
TGCGTCGGGGGCATCCTGGCATTTGATGCCCTGTGCTACAGTAACCAGCCGGTGTCTGAG
AGTCAGAGCAGCAGCCGCCGGGGCAGCGTGGTCAGCATGCAGGACAATGACCTGCTGTCC
CCGGGCATCCTGATGAATGCAGCACACTGCTGCGGTGGTGGCGGTGGCGGCGGTGGCGGT
GGTGGCAGCAGTGGTGGTGGTGGCAGTAGTGGTGGCTCCAGCCTGGAGAGCAGTCGGCAC
CTGAGCCGAAGCAACGTCGACATCCCCCGCAGCAACGGCACTGAGGACCCCAAAAGGCAA
CTGCCCCGCAAGAGGAGCGACTCATCCACCTACGAGCTGGATACCATCCAGCAGCACCAG
GCCTTCCTGTCCAGCCTCCATGCCAGCGTGCTGAGGACTGAGCCCTGCTCACGCCATTCC
AGCAGCTCCACCATGCTGGATGGCACAGGTGCCCTGGGCAGGTTTGACTTTGAGATCACC
GACCTCTTCCTCTTCGGGTGCCCGCTGGGGCTGGTCCTGGCCTTGAGGAAGACTGTCATC
CCAGCCCTGGATGTTTTCCAGCTGCGGCCGGCCTGCCAGCAAGTCTACAACCTCTTCCAC
CCCGCGGACCCGTCAGCTTCACGCCTGGAGCCGCTGCTGGAACGGCGCTTTCACGCCCTG
CCGCCTTTCAGCGTCCCCCGCTACCAACGCTACCCGCTGGGGGATGGCTGCTCCACGCTG
CTGGCGGATGTGCTCCAGACCCACAATGCAGCCTTCCAAGAGCATGGCGCCCCCTCCTCG
CCGGGCACTGCCCCTGCCAGTCGTGGCTTCCGCCGAGCCAGTGAGATCAGCATCGCCAGC
CAGGTGTCAGGCATGGCTGAGAGCTACACGGCATCCAGCATCGCCCAGAAGGCCCCCGAT
GCGCTCAGCCATACCCCCAGCGTCAGGCGTCTGTCCCTGCTCGCCCTGCCCGCCCCCAGC
CCCACCACCCCTGGCCCCCACCCTCCAGCCAGGAAGGCAAGCCCTGGCCTGGAGAGGGCC
CCTGGCCTCCCTGAGCTGGACATTGGAGAAGTCGCTGCAAAGTGGTGGGGCCAGAAGCGG
ATCGACTACGCCCTGTACTGCCCTGACGCCCTCACGGCCTTCCCCACGGTGGCTCTGCCT
CACCTCTTCCACGCCAGCTACTGGGAGTCAACAGACGTGGTCTCCTTTCTGCTGAGACAG
GTCATGAGGCATGACAACTCCAGCATCTTGGAGCTGGATGGCAAGGAAGTGTCGGTGTTC
ACCCCCTCAAAGCCAAGGGAGAAGTGGCAGCGCAAGCGGACCCACGTGAAGCTGCGGAAC
GTGACGGCCAACCACCGGATCAATGATGCCCTTGCCAATGAGGACGGCCCCCAGGTTCTG
ACGGGCAGGTTCATGTATGGGCCCCTGGACATGGTCACCCTGACTGGGGAGAAGGTGGAT
GTGCACATCATGACCCAGCCGCCCTCAGGCGAGTGGCTCTACCTGGATACGCTGGTGACC
AACAACAGTGGGCGTGTCTCCTACACCATCCCTGAGTCGCACCGCCTGGGCGTGGGTGTC
TACCCTATCAAGATGGTGGTCAGGGGAGACCACACGTTTGCCGACAGCTACATCACCGTG
CTGCCCAAGGGCACAGAGTTCGTGGTCTTCAGCATCGACGGTTCCTTTGCCGCTAGCGTG
TCCATCATGGGCAGCGACCCCAAGGTGCGGGCCGGGGCCGTGGACGTGGTGCGGCACTGG
CAGGACCTGGGCTACCTCATCATCTACGTGACGGGCCGGCCCGACATGCAGAAGCAGCGG
GTGGTGGCGTGGCTGGCCCAGCACAACTTCCCCCATGGCGTGGTGTCCTTCTGTGACGGC
CTGGTGCATGACCCGCTGCGGCACAAGGCCAACTTCCTGAAGCTGCTCATCTCCGAGCTG
CACCTGCGCGTGCACGCGGCCTATGGCTCCACCAAGGACGTGGCGGTGTACAGCGCCATT
AGCCTGTCCCCCATGCAGATCTACATCGTGGGCCGGCCCACCAAGAAGCTGCAGCAGCAG
TGCCAGTTCATCACGGATGGCTACGCGGCCCACCTGGCGCAGCTGAAGTACAGCCACCGG
GCGCGGCCCGCTCGCAACACGGCCACCCGCATGGCGCTGCGCAAGGGCAGCTTCGGCCTG
CCCGGCCAGGGCGACTTTCTGCGCTCCCGGAACCACCTGCTTCGCACCATCTCGGCCCAG
CCCAGCGGGCCCAGCCACCGGCACGAGCGGACACAGAGCCAGGCGGATGGCGAGCAGCGG
GGCCAGCGCAGCATGAGTGTGGCGGCCGGCTGCTGGGGCCGCGCCATGACTGGCCGCCTG
GAGCCGGGGGCAGCCGCGGGCCCCAAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 1349 |
| Molecular Weight
| 148931.9 |
| Theoretical pI
| 7.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Membrane-associated phosphatidylinositol transfer protein 2
MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGEGSGVEILENRPYTDGPGGSGQYTH
KVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAG
ENPDVFNLSPVEKNQLTIDFIDIVKDPVPHNEYKTEEDPKLFQSTKTQRGPLSENWIEEY
KKQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLSME
NIRELEKEAQLMLSRKMAQFNEDGEEATELVKHEAVSDQTSGEPPEPSSSNGEPLVGRGL
KKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDTEEMFP
KDITKWSSNDLMDKIESPEPEDTQDGLYRQGAPEFRVASSVEQLNIIEDEVSQPLAAPPS
KIHVLLLVLHGGTILDTGAGDPSSKKGDANTIANVFDTVMRVHYPSALGRLAIRLVPCPP
VCSDAFALVSNLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYG
DFIKSQEGMTFNGQVCLIGDCVGGILAFDALCYSNQPVSESQSSSRRGSVVSMQDNDLLS
PGILMNAAHCCGGGGGGGGGGGSSGGGGSSGGSSLESSRHLSRSNVDIPRSNGTEDPKRQ
LPRKRSDSSTYELDTIQQHQAFLSSLHASVLRTEPCSRHSSSSTMLDGTGALGRFDFEIT
DLFLFGCPLGLVLALRKTVIPALDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHAL
PPFSVPRYQRYPLGDGCSTLLADVLQTHNAAFQEHGAPSSPGTAPASRGFRRASEISIAS
QVSGMAESYTASSIAQKAPDALSHTPSVRRLSLLALPAPSPTTPGPHPPARKASPGLERA
PGLPELDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQ
VMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDALANEDGPQVL
TGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLYLDTLVTNNSGRVSYTIPESHRLGVGV
YPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHW
QDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISEL
HLRVHAAYGSTKDVAVYSAISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYSHR
ARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHERTQSQADGEQR
GQRSMSVAAGCWGRAMTGRLEPGAAAGPK
|
| External Links |
|---|
| GenBank ID Protein
| 24308237 |
| UniProtKB/Swiss-Prot ID
| Q9BZ72 |
| UniProtKB/Swiss-Prot Entry Name
| PITM2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_020845.2 |
| GeneCard ID
| PITPNM2 |
| GenAtlas ID
| PITPNM2 |
| HGNC ID
| HGNC:21044 |
| References |
|---|
| General References
| Not Available |