| Identification |
|---|
| HMDB Protein ID
| CDBP02562 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphatidate phosphatase PPAPDC1A |
| Description
| Not Available |
| Synonyms
|
- Phosphatidic acid phosphatase type 2 domain-containing protein 1A
|
| Gene Name
| PPAPDC1A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol.
|
| GO Classification
|
| Biological Process |
| phospholipid dephosphorylation |
| Cellular Component |
| integral to membrane |
| Component |
| membrane |
| cell part |
| Function |
| catalytic activity |
| Molecular Function |
| phosphatidate phosphatase activity |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10q26.12 |
| SNPs
| PPAPDC1A |
| Gene Sequence
|
>816 bp
ATGCGGGAGCTGGCCATTGAGATCGGGGTGCGAGCCCTGCTCTTCGGAGTCTTCGTTTTT
ACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAA
AATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTC
ACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATT
AAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACT
ATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGA
GTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAA
AGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTAC
TTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGT
GCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTAC
AAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATT
TGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGT
CTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGC
TTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 271 |
| Molecular Weight
| 30394.27 |
| Theoretical pI
| 8.179 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphatidate phosphatase PPAPDC1A
MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFL
TPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDG
VMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLC
AAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVS
LRVPASLKKEERPTADSAPSLPLEGITEGPV
|
| External Links |
|---|
| GenBank ID Protein
| 73611920 |
| UniProtKB/Swiss-Prot ID
| Q5VZY2 |
| UniProtKB/Swiss-Prot Entry Name
| PPC1A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001030059.1 |
| GeneCard ID
| PPAPDC1A |
| GenAtlas ID
| PPAPDC1A |
| HGNC ID
| HGNC:23531 |
| References |
|---|
| General References
| Not Available |