| Identification |
|---|
| HMDB Protein ID
| CDBP02544 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphatidylethanolamine-binding protein 4 |
| Description
| Not Available |
| Synonyms
|
- PEBP-4
- Protein cousin-of-RKIP 1
- hPEBP4
|
| Gene Name
| PEBP4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Lysosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:8 |
| Locus
| 8p21.3 |
| SNPs
| PEBP4 |
| Gene Sequence
|
>684 bp
ATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTC
ACTGGAGACGAGGATGAGAACAGCCCGTGTGCCCATGAGGCCCTCTTGGACGAGGACACC
CTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGGTT
GTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAG
TTCCCGGGGGCCGTGGACGGCGCAACCTATATCCTGGTGATGGTGGATCCAGATGCCCCT
AGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGGGC
GCCGACCTGAAGGAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCC
CCACCGGCACACAGTGGCTTCCATCGCTACCAGTTCTTTGTCTATCTTCAGGAAGGAAAA
GTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGCTCTTGGAAAATGGACAGATTT
CTGAACCGTTTCCACCTGGGCGAACCTGAAGCAAGCACCCAGTTCATGACCCAGAACTAC
CAGGACTCACCAACCCTCCAGGCTCCCAGAGAAAGGGCCAGCGAGCCCAAGCACAAAAAC
CAGGCGGAGATAGCTGCCTGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 227 |
| Molecular Weight
| 25733.2 |
| Theoretical pI
| 6.51 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Phosphatidylethanolamine-binding protein 4
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKV
VPDCNNYRQKITSWMEPIVKFPGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKG
ADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGSWKMDRF
LNRFHLGEPEASTQFMTQNYQDSPTLQAPRERASEPKHKNQAEIAAC
|
| External Links |
|---|
| GenBank ID Protein
| 14585855 |
| UniProtKB/Swiss-Prot ID
| Q96S96 |
| UniProtKB/Swiss-Prot Entry Name
| PEBP4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY037148 |
| GeneCard ID
| PEBP4 |
| GenAtlas ID
| PEBP4 |
| HGNC ID
| HGNC:28319 |
| References |
|---|
| General References
| Not Available |