| Identification |
|---|
| HMDB Protein ID
| CDBP02509 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable saccharopine dehydrogenase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| SCCPDH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| Process |
| metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q44 |
| SNPs
| SCCPDH |
| Gene Sequence
|
>1290 bp
ATGGCGACCGAGCAGAGGCCTTTCCACCTGGTGGTGTTCGGCGCGTCTGGCTTCACCGGC
CAGTTCGTGACCGAGGAGGTGGCCCGGGAGCAGGTGGACCCGGAGCGGAGCTCCCGCCTG
CCCTGGGCCGTGGCGGGCCGCTCCCGGGAGAAGCTGCAGCGGGTGCTGGAGAAGGCGGCC
CTGAAGCTGGGAAGACCAACACTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCT
AATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCGTAGGA
CCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGT
ATCGACATCAGTGGAGAACCTCAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAA
GCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAGCAGAT
CTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTC
CTGACTATACATTCAGGACCTGAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCA
ATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATCTGAAA
CCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAA
CTCAAAGGTTATTCCATTCCTTTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAA
CGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAACTGTG
GGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTG
AGGTTTGGAATTGGAAGGCAACTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTAT
TTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGACATTC
TTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATT
TGTACTCAGGTGAAAGGACCAGAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAG
GCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCTTCACA
CCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAG
TTTAGTGTTATTAGCAGCTCTGAAGTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 429 |
| Molecular Weight
| 47151.0 |
| Theoretical pI
| 9.53 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable saccharopine dehydrogenase
MATEQRPFHLVVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAA
LKLGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASC
IDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESF
LTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRE
LKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFV
RFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKI
CTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNKHGIE
FSVISSSEV
|
| External Links |
|---|
| GenBank ID Protein
| 55770836 |
| UniProtKB/Swiss-Prot ID
| Q8NBX0 |
| UniProtKB/Swiss-Prot Entry Name
| SCPDH_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_016002.2 |
| GeneCard ID
| SCCPDH |
| GenAtlas ID
| SCCPDH |
| HGNC ID
| HGNC:24275 |
| References |
|---|
| General References
| Not Available |