| Identification |
|---|
| HMDB Protein ID
| CDBP02461 |
| Secondary Accession Numbers
| Not Available |
| Name
| S-adenosylmethionine mitochondrial carrier protein |
| Description
| Not Available |
| Synonyms
|
- Mitochondrial S-adenosylmethionine transporter
- Solute carrier family 25 member 26
|
| Gene Name
| SLC25A26 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in binding |
| Specific Function
| Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria.
|
| GO Classification
|
| Biological Process |
| S-adenosylmethionine transport |
| Cellular Component |
| nucleus |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| Function |
| binding |
| Molecular Function |
| S-adenosylmethionine transmembrane transporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3p14.1 |
| SNPs
| SLC25A26 |
| Gene Sequence
|
>825 bp
ATGGACCGGCCGGGGTTCGTGGCAGCGCTGGTGGCTGGTGGGGTAGCAGGTGTTTCTGTT
GACTTGATATTATTTCCTCTGGATACCATTAAAACCAGGCTGCAGAGTCCCCAAGGATTT
AATAAGGCTGGTGGTTTTCATGGAATATATGCTGGCGTTCCTTCTGCTGCTATTGGATCC
TTTCCTAATGCTGCTGCATTTTTTATCACCTATGAATATGTGAAGTGGTTTTTGCATGCT
GATTCATCTTCATATTTGACACCTATGAAACATATGTTGGCTGCCTCTGCTGGAGAAGTG
GTTGCCTGCCTGATTCGAGTTCCATCTGAAGTGGTTAAGCAGAGGGCACAGGTATCTGCT
TCTACAAGAACATTTCAGATTTTCTCTAACATCTTATATGAAGAGGGTATCCAAGGGTTG
TATCGAGGCTATAAAAGCACAGTTTTAAGAGAGATTCCTTTTTCTTTGGTCCAGTTTCCC
TTATGGGAGTCCTTAAAAGCCCTCTGGTCCTGGAGGCAGGATCATGTGGTGGATTCTTGG
CAGTCAGCAGTCTGTGGAGCTTTTGCAGGTGGATTTGCCGCTGCAGTCACCACCCCTCTA
GACGTGGCAAAGACAAGAATTACGCTGGCAAAGGCTGGCTCCAGCACTGCTGATGGGAAT
GTGCTCTCTGTCCTGCATGGGGTCTGGCGGTCACAGGGGCTGGCAGGATTATTTGCAGGT
GTCTTCCCTCGAATGGCAGCCATCAGTCTGGGAGGTTTCATCTTTCTGGGGGCTTATGAC
CGAACGCACAGCTTGCTGTTGGAAGTTGGCAGAAAGAGTCCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 274 |
| Molecular Weight
| 20116.095 |
| Theoretical pI
| 9.6 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>S-adenosylmethionine mitochondrial carrier protein
MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKAGGFHGIYAGVPSAAIGS
FPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSA
STRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVDSW
QSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAG
VFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
|
| External Links |
|---|
| GenBank ID Protein
| 41351486 |
| UniProtKB/Swiss-Prot ID
| Q70HW3 |
| UniProtKB/Swiss-Prot Entry Name
| SAMC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ580932 |
| GeneCard ID
| SLC25A26 |
| GenAtlas ID
| SLC25A26 |
| HGNC ID
| HGNC:20661 |
| References |
|---|
| General References
| Not Available |