| Identification |
| HMDB Protein ID
| CDBP02398 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma |
| Description
| Not Available |
| Synonyms
|
- PI(5)P 4-kinase type II gamma
- PIP4KII-gamma
- Phosphatidylinositol-5-phosphate 4-kinase type II gamma
|
| Gene Name
| PIP4K2C |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in phosphatidylinositol phosphate kinase activity |
| Specific Function
| May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum |
| GO Classification
|
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| phosphatidylinositol phosphate kinase activity |
| lipid kinase activity |
| Process |
| metabolic process |
| phosphatidylinositol metabolic process |
| organophosphate metabolic process |
| phospholipid metabolic process |
| glycerophospholipid metabolic process |
| phosphoinositide metabolic process |
|
| Cellular Location
|
- Cytoplasm
- Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 12q13.3 |
| SNPs
| PIP4K2C |
| Gene Sequence
|
>1266 bp
ATGGCGTCCTCCTCGGTCCCACCAGCCACGGTATCGGCGGCGACAGCAGGCCCCGGCCCA
GGTTTCGGCTTCGCCTCCAAGACCAAGAAGAAGCATTTCGTGCAGCAGAAGGTGAAGGTG
TTCCGGGCGGCCGACCCGCTGGTGGGTGTGTTCCTGTGGGGCGTAGCCCACTCGATCAAT
GAGCTCAGCCAGGTGCCTCCCCCGGTGATGCTGCTGCCAGATGACTTTAAGGCCAGCTCC
AAGATCAAGGTCAACAATCACCTTTTCCACAGGGAAAATCTGCCCAGTCATTTCAAGTTC
AAGGAGTATTGTCCCCAGGTCTTCAGGAACCTCCGTGATCGATTTGGCATTGATGACCAA
GATTACTTGGTGTCCCTTACCCGAAACCCCCCCAGCGAAAGTGAAGGCAGTGATGGTCGC
TTCCTTATCTCCTACGATCGGACTCTGGTCATCAAAGAAGTATCCAGTGAGGACATTGCT
GACATGCATAGCAACCTCTCCAACTATCACCAGTACATTGTGAAGTGCCATGGCAACACG
CTTCTGCCCCAGTTCCTGGGGATGTACCGAGTCAGTGTGGACAACGAAGACAGCTACATG
CTTGTGATGCGCAATATGTTTAGCCACCGTCTTCCTGTGCACAGGAAGTATGACCTCAAG
GGTTCCCTAGTGTCCCGGGAAGCCAGCGATAAGGAAAAGGTTAAAGAATTGCCCACCCTT
AAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAA
ATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGAC
TACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCG
CCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCT
CTGGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGG
CCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAA
GGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGAT
GCCAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATC
TCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTT
GCCTAA
|
| Protein Properties |
| Number of Residues
| 421 |
| Molecular Weight
| 47285.5 |
| Theoretical pI
| 6.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEG
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
A
|
| External Links |
| GenBank ID Protein
| 226371739 |
| UniProtKB/Swiss-Prot ID
| Q8TBX8 |
| UniProtKB/Swiss-Prot Entry Name
| PI42C_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001146258.1 |
| GeneCard ID
| PIP4K2C |
| GenAtlas ID
| PIP4K2C |
| HGNC ID
| HGNC:23786 |
| References |
| General References
| Not Available |