Showing Protein V-type proton ATPase subunit C 2 (CDBP02395)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP02395
Secondary Accession Numbers Not Available
Name V-type proton ATPase subunit C 2
Description Not Available
Synonyms
  1. V-ATPase subunit C 2
  2. Vacuolar proton pump subunit C 2
Gene Name ATP6V1C2
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Specific Function Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells
GO Classification
Component
proton-transporting two-sector atpase complex, catalytic domain
proton-transporting v-type atpase, v1 domain
macromolecular complex
protein complex
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
hydrolase activity, acting on acid anhydrides
Process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs ATP6V1C2
Gene Sequence 
>1284 bp
ATGTCGGAGTTTTGGTTAATTTCTGCCCCTGGCGATAAGGAAAATTTGCAAGCTCTGGAG
AGGATGAATACTGTAACCTCCAAGTCCAACCTGTCTTATAATACCAAATTCGCTATTCCT
GACTTCAAGGTGGGGACCTTGGATTCCCTGGTTGGCCTCTCTGATGAGTTGGGGAAACTC
GACACCTTTGCTGAAAGCCTCATAAGGAGAATGGCTCAGAGCGTGGTGGAAGTCATGGAG
GACTCAAAGGGGAAGGTCCAGGAGCACCTCCTGGCAAACGGAGTTGACTTAACATCCTTT
GTGACCCACTTTGAATGGGACATGGCCAAATATCCTGTCAAGCAGCCGCTCGTGAGTGTG
GTGGACACAATAGCCAAGCAACTGGCGCAGATCGAGATGGACCTGAAGTCCCGAACGGCC
GCCTACAACACTCTGAAGACAAACCTGGAGAACCTGGAAAAGAAATCCATGGGGAACCTC
TTCACCCGGACACTGAGTGATATTGTGAGCAAAGAGGACTTCGTGCTGGATTCTGAATAT
CTCGTCACACTTCTGGTCATCGTCCCCAAACCAAACTACTCACAATGGCAAAAAACCTAC
GAATCTCTCTCAGACATGGTGGTCCCTCGATCAACCAAACTCATTACTGAGGACAAGGAA
GGGGGCCTTTTCACTGTGACTCTGTTTCGAAAAGTGATTGAAGATTTCAAAACCAAGGCC
AAAGAAAACAAGTTCACTGTTCGTGAATTTTACTATGATGAGAAGGAAATTGAAAGGGAA
AGGGAGGAGATGGCCAGATTGCTGTCTGATAAGAAGCAACAGTATCAAACTTCCTGTGTT
GCTCTTAAAAAGGGATCATCCACCTTCCCGGACCACAAGGTTAAGGTAACCCCGCTAGGT
AACCCTGATAGGCCTGCTGCGGGGCAGACCGACAGAGAGAGAGAGAGTGAGGGCGAGGGT
GAGGGCCCCCTGCTGCGCTGGCTCAAGGTGAACTTCAGTGAAGCCTTCATTGCCTGGATC
CACATCAAGGCCCTGAGAGTGTTTGTGGAGTCCGTGCTCAGGTATGGACTACCAGTGAAC
TTCCAGGCAGTGCTCCTGCAGCCGCATAAGAAGTCATCCACCAAGCGTTTAAGAGAGGTT
CTAAACTCTGTCTTCCGACATCTGGATGAAGTAGCCGCTACAAGTATACTGGATGCATCT
GTGGAGATCCCGGGACTGCAACTCAATAACCAAGACTATTTTCCTTATGTCTACTTCCAT
ATTGACCTTAGTCTTCTTGACTAG
Protein Properties
Number of Residues 427
Molecular Weight 48758.4
Theoretical pI 5.99
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>V-type proton ATPase subunit C 2
MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKL
DTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSV
VDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEY
LVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKA
KENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLG
NPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVN
FQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFH
IDLSLLD
GenBank ID Protein 87159812
UniProtKB/Swiss-Prot ID Q8NEY4
UniProtKB/Swiss-Prot Entry Name VATC2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001039362.1
GeneCard ID ATP6V1C2
GenAtlas ID ATP6V1C2
HGNC ID HGNC:18264
References
General References Not Available