Cannabis Compound Database: Showing Protein V-type proton ATPase subunit E 2 (CDBP02394)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP02394

Secondary Accession Numbers

Not Available

Name

V-type proton ATPase subunit E 2

Description

Not Available

Synonyms

V-ATPase subunit E 2
Vacuolar proton pump subunit E 2

Gene Name

ATP6V1E2

Protein Type

Enzyme

Biological Properties

General Function

Involved in proton-transporting ATPase activity, rotational mechanism

Specific Function

Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome

GO Classification

Component
proton-transporting two-sector atpase complex, catalytic domain
macromolecular complex
protein complex
Function
proton-transporting atpase activity, rotational mechanism
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
transporter activity
Process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

2p21

SNPs

ATP6V1E2

Gene Sequence

>681 bp
ATGGCCCTGAGTGATGTCGATGTGAAAAAGCAGATTAAGCACATGATGGCTTTCATTGAG
CAGGAAGCCAATGAGAAAGCAGAGGAAATCGATGCCAAGGCTGAGGAAGAGTTTAACATT
GAGAAAGGACGCCTCGTGCAAACCCAACGACTGAAGATTATGGAGTATTATGAGAAAAAG
GAGAAGCAGATAGAGCAGCAGAAGAAAATCCTGATGTCCACCATGAGGAATCAGGCGAGG
CTGAAAGTCCTGAGAGCCCGAAATGACCTCATCTCAGATTTGCTCAGTGAGGCGAAGCTG
AGACTCAGCAGGATTGTGGAGGACCCAGAGGTCTACCAGGGGCTGCTGGATAAACTGGTG
CTCCAGGGTCTGCTCCGACTGCTGGAACCTGTGATGATTGTACGCTGCCGGCCACAAGAC
CTCCTCCTGGTGGAGGCTGCTGTACAAAAAGCCATCCCCGAGTACATGACAATTTCCCAG
AAACATGTGGAGGTCCAGATTGATAAAGAGGCATACCTGGCTGTGAATGCAGCTGGAGGT
GTGGAGGTCTACAGTGGCAATCAGAGAATAAAGGTTTCAAATACCTTGGAAAGCCGACTG
GATCTCTCAGCCAAGCAAAAGATGCCAGAAATACGAATGGCCTTGTTTGGTGCTAACACC
AACAGAAAGTTCTTTATATAA

Protein Properties

Number of Residues

226

Molecular Weight

26074.3

Theoretical pI

9.24

Pfam Domain Function

vATP-synt_E (PF01991 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>V-type proton ATPase subunit E 2
MALSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
EKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLV
LQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGG
VEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI

External Links

GenBank ID Protein

21392390

UniProtKB/Swiss-Prot ID

Q96A05

UniProtKB/Swiss-Prot Entry Name

VATE2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB074759

GeneCard ID