Showing Protein V-type proton ATPase subunit d 2 (CDBP02393)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP02393
Secondary Accession Numbers Not Available
Name V-type proton ATPase subunit d 2
Description Not Available
Synonyms
  1. V-ATPase subunit d 2
  2. Vacuolar proton pump subunit d 2
Gene Name ATP6V0D2
Protein Type Enzyme
Biological Properties
General Function Involved in hydrogen ion transmembrane transporter activity
Specific Function Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis
GO Classification
Component
macromolecular complex
protein complex
proton-transporting two-sector atpase complex, proton-transporting domain
proton-transporting v-type atpase, v0 domain
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
transporter activity
Process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs ATP6V0D2
Gene Sequence 
>1053 bp
ATGCTCGAAGGTGCGGAGCTGTACTTCAACGTGGACCATGGCTACCTGGAGGGCCTGGTT
CGAGGATGCAAGGCCAGCCTCCTGACCCAGCAAGACTATATCAACCTGGTCCAGTGTGAG
ACCCTAGAAGACCTGAAAATTCATCTCCAGACTACTGATTATGGTAACTTTTTGGCTAAT
CACACAAATCCTCTTACTGTTTCCAAAATTGACACTGAGATGAGGAAAAGACTATGTGGA
GAATTTGAGTATTTCCGGAATCATTCCCTGGAGCCCCTCAGCACATTTCTCACCTATATG
ACGTGCAGTTATATGATAGACAATGTGATTCTGCTGATGAATGGTGCATTGCAGAAAAAA
TCTGTGAAAGAAATTCTGGGGAAGTGCCACCCCTTGGGCCGTTTCACAGAAATGGAAGCT
GTCAACATTGCAGAGACACCTTCAGATCTCTTTAATGCCATTCTGATCGAAACGCCATTA
GCTCCATTCTTCCAAGACTGCATGTCTGAAAATGCTCTAGATGAACTGAATATTGAATTG
CTACGCAATAAACTATACAAGTCTTACCTTGAGGCATTCTATAAATTCTGTAAGAATCAT
GGTGATGTCACAGCAGAAGTTATGTGTCCCATTCTTGAGTTTGAGGCCGACAGACGTGCT
TTTATCATCACTCTTAACTCCTTTGGCACTGAATTGAGCAAAGAAGACCGAGAGACCCTC
TATCCAACCTTCGGCAAACTCTATCCTGAGGGGTTGCGGCTGTTGGCTCAAGCAGAAGAC
TTTGACCAGATGAAGAACGTAGCGGATCATTACGGAGTATACAAACCTTTATTTGAAGCT
GTAGGTGGCAGTGGGGGAAAGACATTGGAGGACGTGTTTTACGAGCGTGAGGTACAAATG
AATGTGCTGGCATTCAACAGACAGTTCCACTACGGTGTGTTTTATGCATATGTAAAGCTG
AAGGAACAGGAAATTAGAAATATTGTGTGGATAGCAGAATGTATTTCACAGAGGCATCGA
ACTAAAATCAACAGTTACATTCCAATTTTATAA
Protein Properties
Number of Residues 350
Molecular Weight 40426.0
Theoretical pI 4.97
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>V-type proton ATPase subunit d 2
MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLAN
HTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKK
SVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIEL
LRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETL
YPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQM
NVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL
GenBank ID Protein 21755413
UniProtKB/Swiss-Prot ID Q8N8Y2
UniProtKB/Swiss-Prot Entry Name VA0D2_HUMAN
PDB IDs Not Available
GenBank Gene ID AK096027
GeneCard ID ATP6V0D2
GenAtlas ID ATP6V0D2
HGNC ID HGNC:18266
References
General References Not Available