| Identification |
|---|
| HMDB Protein ID
| CDBP02353 |
| Secondary Accession Numbers
| Not Available |
| Name
| L-lactate dehydrogenase C chain |
| Description
| Not Available |
| Synonyms
|
- CT32
- Cancer/testis antigen 32
- LDH testis subunit
- LDH-C
- LDH-X
|
| Gene Name
| LDHC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| Specific Function
| Possible role in sperm motility.
|
| GO Classification
|
| Biological Process |
| sperm motility |
| ATP biosynthetic process |
| lactate biosynthetic process from pyruvate |
| lactate oxidation |
| glycolysis |
| cellular carbohydrate metabolic process |
| Cellular Component |
| cytoplasm |
| microtubule-based flagellum |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| catalytic activity |
| lactate dehydrogenase activity |
| l-lactate dehydrogenase activity |
| oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor |
| oxidoreductase activity, acting on ch-oh group of donors |
| oxidoreductase activity |
| Molecular Function |
| L-lactate dehydrogenase activity |
| nucleotide binding |
| Process |
| carbohydrate metabolic process |
| cellular carbohydrate metabolic process |
| small molecule metabolic process |
| alcohol metabolic process |
| monosaccharide metabolic process |
| hexose metabolic process |
| glucose metabolic process |
| oxidation reduction |
| glucose catabolic process |
| glycolysis |
| metabolic process |
| primary metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | pyruvate fermentation to lactate | Not Available | Not Available | | Glycolysis / Gluconeogenesis | Not Available |  | | Cysteine and methionine metabolism | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| 11p15.1 |
| SNPs
| LDHC |
| Gene Sequence
|
>999 bp
ATGTCAACTGTCAAGGAGCAGCTAATTGAGAAGCTAATTGAGGATGATGAAAACTCCCAG
TGTAAAATTACTATTGTTGGAACTGGTGCCGTAGGCATGGCTTGTGCTATTAGTATCTTA
CTGAAGGATTTGGCTGATGAACTTGCCCTTGTTGATGTTGCATTGGACAAACTGAAGGGA
GAAATGATGGATCTTCAGCATGGCAGTCTTTTCTTTAGTACTTCAAAGGTTACTTCTGGA
AAAGATTACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAG
CAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATGTGGCTATAATGAAAATAATC
ATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTG
GATATTTTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGA
AGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAATTGGAGAAAAGTTGGGTGTC
CACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTA
TGGAGTGGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACG
GATTCAGATAAGGAACACTGGAAAAATATCCATAAACAAGTTATTCAAAGTGCCTATGAA
ATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATCTGGTA
GGATCCATTTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTA
TATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTC
TCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCA
GAAACACTTTGGAATATTCAAAAGGATCTAATATTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 332 |
| Molecular Weight
| 36310.965 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>L-lactate dehydrogenase C chain
MSTVKEQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKG
EMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSI
IPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGV
HPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYE
IIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGV
SDVVKINLNSEEEALFKKSAETLWNIQKDLIF
|
| External Links |
|---|
| GenBank ID Protein
| 307120 |
| UniProtKB/Swiss-Prot ID
| P07864 |
| UniProtKB/Swiss-Prot Entry Name
| LDHC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| J02938 |
| GeneCard ID
| LDHC |
| GenAtlas ID
| LDHC |
| HGNC ID
| HGNC:6544 |
| References |
|---|
| General References
| Not Available |