Cannabis Compound Database: Showing Protein Cardiolipin synthase (CDBP02348)

Identification Biological properties Gene properties Protein properties External links References XML Show 0 compounds

Identification

HMDB Protein ID

CDBP02348

Secondary Accession Numbers

Not Available

Name

Cardiolipin synthase

Description

Not Available

Synonyms

CLS
Protein GCD10 homolog

Gene Name

CRLS1

Protein Type

Enzyme

Biological Properties

General Function

Involved in phosphotransferase activity, for other substituted phosphate groups

Specific Function

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.

GO Classification

Biological Process
small molecule metabolic process
cardiolipin biosynthetic process
phosphatidylglycerol acyl-chain remodeling
Cellular Component
integral to membrane
mitochondrial inner membrane
Component
membrane
cell part
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, for other substituted phosphate groups
Molecular Function
phosphotransferase activity, for other substituted phosphate groups
Process
metabolic process
phospholipid biosynthetic process
organophosphate metabolic process
phospholipid metabolic process

Cellular Location

Mitochondrion inner membrane
Multi-pass membrane protein

Pathways

Name	SMPDB/Pathwhiz	KEGG
Phospholipid Biosynthesis
Glycerophospholipid metabolism	Not Available
Cardiolipin Biosynthesis CL(i-13:0/i-16:0/i-13:0/i-17:0)		Not Available
Cardiolipin Biosynthesis CL(i-14:0/i-15:0/i-20:0/i-18:0)		Not Available
Cardiolipin Biosynthesis CL(a-13:0/i-12:0/a-15:0/i-12:0)		Not Available

Gene Properties

Chromosome Location

Locus

20p13-p12.3

SNPs

CRLS1

Gene Sequence

>906 bp
ATGCTAGCCTTGCGCGTGGCGCGCGGCTCGTGGGGGGCCCTGCGCGGCGCCGCTTGGGCT
CCGGGAACGCGGCCGAGTAAGCGACGCGCCTGCTGGGCCCTGCTGCCGCCCGTGCCCTGC
TGCTTGGGCTGCCTGGCCGAACGCTGGAGGCTGCGTCCGGCCGCTCTTGGCTTGCGGCTG
CCCGGGATCGGCCAGCGGAACCACTGTTCGGGCGCGGGGAAGGCGGCTCCCAGGCCAGCG
GCCGGAGCGGGCGCCGCTGCCGAAGCCCCGGGCGGCCAGTGGGGCCCGGCGAGCACCCCC
AGCCTGTATGAAAACCCATGGACAATCCCGAATATGTTGTCAATGACGAGAATTGGCTTG
GCCCCAGTTCTGGGCTATTTGATTATTGAAGAAGATTTTAATATTGCACTAGGAGTTTTT
GCTTTAGCTGGACTAACAGATTTGTTGGATGGATTTATTGCTCGAAACTGGGCCAATCAA
AGATCAGCTTTGGGAAGTGCTCTTGATCCACTTGCTGATAAAATACTTATCAGTATCTTA
TATGTTAGCTTGACCTATGCAGATCTTATTCCAGTTCCACTTACTTACATGATCATTTCG
AGAGATGTAATGTTGATTGCTGCTGTTTTTTATGTCAGATACCGAACTCTTCCAACACCA
CGAACACTTGCCAAGTATTTCAATCCTTGCTATGCCACTGCTAGGTTAAAACCAACATTC
ATCAGCAAGGTGAATACAGCAGTCCAGTTAATCTTGGTGGCAGCTTCTTTGGCAGCTCCA
GTTTTCAACTATGCTGACAGCATTTATCTTCAGATACTATGGTGTTTTACAGCTTTCACC
ACAGCTGCATCAGCTTATAGTTACTATCATTATGGCCGGAAGACTGTTCAGGTGATAAAA
GACTGA

Protein Properties

Number of Residues

301

Molecular Weight

22583.205

Theoretical pI

8.683

Pfam Domain Function

CDP-OH_P_transf (PF01066 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Cardiolipin synthase
MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRL
PGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGL
APVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISIL
YVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTF
ISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIK
D

External Links

GenBank ID Protein

12005485

UniProtKB/Swiss-Prot ID

Q9UJA2

UniProtKB/Swiss-Prot Entry Name

CRLS1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF241784

GeneCard ID