| Identification |
|---|
| HMDB Protein ID
| CDBP02344 |
| Secondary Accession Numbers
| Not Available |
| Name
| Sodium-coupled neutral amino acid transporter 5 |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 38 member 5
- System N transporter 2
|
| Gene Name
| SLC38A5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH- sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glutaminolysis and Cancer |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SLC38A5 |
| Gene Sequence
|
>1419 bp
ATGGAACTGCAGGATCCAAAGATGAATGGAGCCCTCCCTTCGGATGCTGTGGGCTACAGG
CAAGAACGTGAGGGCTTCCTGCCCAGTCGTGGTCCTGCTCCTGGGAGCAAGCCGGTCCAG
TTCATGGATTTCGAGGGGAAGACATCGTTTGGAATGTCAGTGTTCAACCTCAGCAACGCC
ATCATGGGCAGCGGCATCCTGGGGCTGGCCTATGCCATGGCCCACACGGGGGTCATCTTC
TTCCTGGCCCTGCTGCTGTGCATTGCGCTTCTGTCGTCCTACTCCATCCACCTCCTGCTG
ACCTGTGCTGGTATTGCAGGCATCCGAGCCTATGAGCAGCTGGGACAGAGGGCATTCGGG
CCTGCGGGGAAGGTAGTGGTGGCCACAGTCATCTGTCTGCACAATGTTGGGGCCATGTCC
AGTTACCTGTTCATCATCAAATCTGAGCTCCCCCTGGTTATCGGCACCTTCCTGTACATG
GACCCCGAGGGGGACTGGTTCTTGAAGGGAAACCTCCTCATCATCATCGTCAGTGTGTTA
ATCATCCTGCCCCTCGCCCTCATGAAACACTTGGGCTACCTGGGGTACACCAGTGGTCTC
TCTCTGACCTGCATGCTGTTTTTCCTTGTTTCGGTCATCTACAAGAAGTTCCAACTTGGC
TGTGCTATAGGCCACAATGAAACAGCAATGGAGAGTGAAGCTCTCGTGGGACTCCCCAGC
CAAGGACTCAACAGCAGCTGTGAGGCCCAGATGTTCACAGTTGACTCACAGATGTCCTAC
ACAGTGCCCATTATGGCTTTTGCTTTTGTCTGCCACCCTGAGGTGCTGCCCATCTATACG
GAGCTCTGCCGGCCCTCCAAGCGCAGGATGCAGGCCGTGGCCAACGTGTCCATTGGGGCC
ATGTTCTGCATGTATGGGCTCACAGCAACCTTTGGATACCTCACCTTCTACAGCAGTGTG
AAGGCGGAGATGCTGCACATGTACAGCCAGAAGGACCCGCTCATCCTCTGTGTGCGCCTG
GCCGTGCTGCTCGCGGTGACCCTCACTGTGCCAGTCGTGCTGTTCCCTATCCGCCGGGCC
CTGCAGCAGCTGCTTTTCCCAGGCAAGGCCTTCAGCTGGCCACGACATGTGGCCATAGCT
CTGATCCTGCTTGTTTTGGTCAATGTCCTTGTCATCTGTGTGCCAACCATCCGGGATATC
TTTGGAGTTATCGGGTCCACCTCAGCCCCCAGCCTCATCTTCATCCTCCCCAGCATCTTC
TACCTCCGCATTGTACCCTCTGAGGTGGAGCCTTTCTTATCCTGGCCCAAGATCCAGGCC
CTGTGCTTTGGAGTCCTGGGAGTCCTCTTCATGGCCGTCAGTCTAGGCTTTATGTTTGCC
AACTGGGCCACAGGCCAGAGCCGCATGTCTGGACACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 472 |
| Molecular Weight
| 51456.9 |
| Theoretical pI
| 8.28 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["49-71", "88-108", "126-146", "167-187", "193-213", "258-278", "296-316", "335-355", "377-397", "400-420", "440-460"]
|
| Protein Sequence
|
>Sodium-coupled neutral amino acid transporter 5
MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNA
IMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFG
PAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVL
IILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPS
QGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGA
MFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRA
LQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIF
YLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH
|
| External Links |
|---|
| GenBank ID Protein
| 193788624 |
| UniProtKB/Swiss-Prot ID
| Q8WUX1 |
| UniProtKB/Swiss-Prot Entry Name
| S38A5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_033518.2 |
| GeneCard ID
| SLC38A5 |
| GenAtlas ID
| SLC38A5 |
| HGNC ID
| HGNC:18070 |
| References |
|---|
| General References
| Not Available |