| Identification |
|---|
| HMDB Protein ID
| CDBP02275 |
| Secondary Accession Numbers
| Not Available |
| Name
| Pyrroline-5-carboxylate reductase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| P5CR2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| L-proline + NAD(P)(+) = 1-pyrroline-5- carboxylate + NAD(P)H |
| GO Classification
|
| Function |
| catalytic activity |
| pyrroline-5-carboxylate reductase activity |
| oxidoreductase activity, acting on the ch-nh group of donors |
| oxidoreductase activity, acting on the ch-nh group of donors, nad or nadp as acceptor |
| oxidoreductase activity |
| Process |
| metabolic process |
| cellular metabolic process |
| glutamine family amino acid metabolic process |
| proline metabolic process |
| proline biosynthetic process |
| oxidation reduction |
| cellular amino acid and derivative metabolic process |
| cellular amino acid metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| P5CR2 |
| Gene Sequence
|
>960 bp
ATGAGCGTGGGCTTCATCGGGGCCGGCCAGCTGGCTATGCTCTGGCGCGGGGCTTCACGG
CCGCAGATTCCTGTCGGCTCACAAGATAATAGCCAGCTCCCCAGAAATGAACCTGCCCAC
GGTGTCCGCGCTCAGGAAGATGGGTGTGAACCTGACACGCAGCAACAAGGAGACGGTGAA
GCACAGCGACGTCCTGTTTCTGGCTGTGAAGCACATATCATCCCCTTCATCCTGGTTGAG
ATTGGGGCCGACGTGCAAGCCAGACACATCGTGGTCTCCTGTGCGGCTGGTGTTACCATC
AGCTCTGTGGAGAAGAAGCTGATGGAATTCCAGCCAGCCCCCAAAGTGATTCGCTGCATG
ACCAACACACCTGTGGTAGTGCAGGAAGGCGCTACAGTGTACGCCACGGGCACCCATGCC
CTGGTGGAGGATGGGCAGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCTGCACTGAG
GTGGAAGAGGACCTCATCGATGCCGTCACGGGGCTCAGTGGCAGCAAACCTGCCTATGCA
TTCATGGCTCTGGACGCATTGGCTGATGGTGGGGTGAAGATGGGTTTGCCACGGCGCCTG
GCAATCCAACTCGGGGCCCAGGCTTTGCTGGGAGCTGCCAAGATGCTGCTGGACTCGGAG
CAGCATCCATGCCAGCTTAAGGACAATGTCTGCTCCCCTGGGGGAGCCACCATCCACGCC
CTGCACTTTCTAGAGAGTGGGGGCTTCCGCTCTCTGCTCATCAATGCAGTTGAGGCCTCC
TGTATCCGAACACGAGAGCTACAGTCCATGGCCGACCAAGAAAAGATCTCCCCAGCTGCC
CTTAAGAAGACCCTCTTAGACAGAGTGAAGCTGGAATCCCCCACAGTCTCCACACTGACC
CCCTCCAGCCCAGGGAAGCTCCTCACAAGAAGCCTGGCCCTGGGAGGCAAGAAGGACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 319 |
| Molecular Weight
| 33726.4 |
| Theoretical pI
| 5.91 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Pyrroline-5-carboxylate reductase
MSVGFIGAGQLAMLWRGASRPQIPVGSQDNSQLPRNEPAHGVRAQEDGCEPDTQQQGDGE
AQRRPVSGCEAHIIPFILVEIGADVQARHIVVSCAAGVTISSVEKKLMEFQPAPKVIRCM
TNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSKPAYA
FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHA
LHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLT
PSSPGKLLTRSLALGGKKD
|
| External Links |
|---|
| GenBank ID Protein
| 4960118 |
| UniProtKB/Swiss-Prot ID
| Q4W8W1 |
| UniProtKB/Swiss-Prot Entry Name
| Q4W8W1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF151351 |
| GeneCard ID
| P5CR2 |
| GenAtlas ID
| P5CR2 |
| HGNC ID
| HGNC:30262 |
| References |
|---|
| General References
| Not Available |