| Identification |
|---|
| HMDB Protein ID
| CDBP02247 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial glutamate carrier 2 |
| Description
| Not Available |
| Synonyms
|
- GC-2
- Glutamate/H(+) symporter 2
- Solute carrier family 25 member 18
|
| Gene Name
| SLC25A18 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in binding |
| Specific Function
| Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+).
|
| GO Classification
|
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| mitochondrial inner membrane |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| Function |
| binding |
| Molecular Function |
| symporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| 22q11.2 |
| SNPs
| SLC25A18 |
| Gene Sequence
|
>948 bp
ATGACCCACCAGGATCTGAGCATCACAGCCAAACTCATCAATGGAGGTGTAGCAGGGCTC
GTGGGGGTGACCTGCGTGTTCCCCATCGACTTGGCCAAGACTCGCCTGCAGAACCAGCAT
GGGAAAGCCATGTACAAAGGAATGATCGACTGCCTGATGAAGACGGCTCGGGCGGAGGGC
TTCTTCGGCATGTACCGAGGGGCTGCAGTGAACCTCACTCTGGTCACTCCAGAGAAGGCC
ATCAAGCTGGCGGCCAACGACTTTTTCCGGCGGCTGCTCATGGAAGATGGGATGCAGCGG
AACCTGAAGATGGAGATGCTTGCCGGGTGTGGGGCTGGGATGTGCCAGGTCGTGGTGACC
TGTCCCATGGAAATGCTCAAGATTCAGCTGCAGGATGCTGGACGCCTGGCCGTCCATCAT
CAGGGCTCGGCCTCAGCACCCTCCACCTCCAGGTCCTACACAACTGGTTCGGCTTCCACC
CACAGGCGCCCCTCTGCCACCCTCATTGCCTGGGAGCTGCTCCGCACTCAGGGCCTGGCT
GGGCTCTACAGGGGCCTGGGTGCCACTCTCCTCAGAGACATTCCTTTCTCCATCATCTAC
TTCCCACTGTTTGCCAACCTTAACAACCTGGGGTTCAACGAGCTCGCCGGTAAGGCGTCC
TTTGCACATTCCTTCGTGTCAGGCTGTGTGGCAGGTTCCATAGCTGCGGTCGCAGTGACG
CCTCTAGATGTTCTGAAAACTCGAATCCAAACCCTCAAGAAAGGCCTGGGCGAGGACATG
TACAGTGGGATCACCGACTGTGCCAGGAAACTCTGGATTCAGGAGGGACCATCTGCCTTC
ATGAAAGGCGCTGGCTGCCGGGCACTGGTCATAGCACCTCTCTTTGGGATTGCTCAAGGG
GTCTATTTTATTGGGATTGGAGAGCGCATCTTAAAGTGTTTTGACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 315 |
| Molecular Weight
| 33848.44 |
| Theoretical pI
| 9.242 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mitochondrial glutamate carrier 2
MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG
FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT
CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA
GLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVT
PLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQG
VYFIGIGERILKCFD
|
| External Links |
|---|
| GenBank ID Protein
| 21322707 |
| UniProtKB/Swiss-Prot ID
| Q9H1K4 |
| UniProtKB/Swiss-Prot Entry Name
| GHC2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ428203 |
| GeneCard ID
| SLC25A18 |
| GenAtlas ID
| SLC25A18 |
| HGNC ID
| HGNC:10988 |
| References |
|---|
| General References
| Not Available |