Cannabis Compound Database: Showing Protein Myotubularin-related protein 3 (CDBP02207)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP02207

Secondary Accession Numbers

Not Available

Name

Myotubularin-related protein 3

Description

Not Available

Synonyms

FYVE domain-containing dual specificity protein phosphatase 1
FYVE-DSP1
Zinc finger FYVE domain-containing protein 10

Gene Name

MTMR3

Protein Type

Metal Binding

Biological Properties

General Function

Involved in phosphatase activity

Specific Function

Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues.

GO Classification

Biological Process
small molecule metabolic process
phosphatidylinositol biosynthetic process
phosphatidylinositol dephosphorylation
Cellular Component
membrane
cytosol
nucleus
Function
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
ion binding
cation binding
metal ion binding
hydrolase activity, acting on ester bonds
binding
catalytic activity
hydrolase activity
transition metal ion binding
zinc ion binding
phosphoric ester hydrolase activity
phosphatase activity
Molecular Function
phosphatidylinositol-3-phosphatase activity
protein tyrosine phosphatase activity
protein serine/threonine phosphatase activity
metal ion binding
Process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation
metabolic process
cellular metabolic process

Cellular Location

Cytoplasm
Peripheral membrane protein
Membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

22q12.2

SNPs

MTMR3

Gene Sequence

>3597 bp
ATGGATGAAGAGACTCGGCACAGCCTTGAGTGCATCCAGGCCAATCAGATCTTTCCCAGG
AAGCAGCTGATCCGGGAGGATGAGAATCTTCAGGTTCCTTTCCTTGAACTTCATGGAGAG
AGCACAGAGTTTGTGGGCCGTGCCGAGGATGCCATCATTGCCCTTTCCAATTACAGACTT
CACATCAAGTTCAAGGAGTCTCTTGTTAATGTTCCATTACAGCTTATAGAAAGTGTTGAA
TGCCGAGATATATTTCAGCTTCATTTGACTTGCAAAGACTGCAAAGTTATCAGGTGTCAG
TTTTCAACCTTTGAGCAGTGTCAAGAGTGGCTGAAGAGACTGAACAACGCAATCCGACCA
CCTGCTAAAATAGAAGATCTCTTCTCATTTGCATACCATGCTTGGTGCATGGAGGTCTAT
GCCAGTGAAAAAGAGCAACATGGAGACCTGTGCAGACCAGGGGAGCATGTAACTTCAAGG
TTTAAAAACGAGGTGGAGAGGATGGGTTTTGATATGAACAACGCCTGGAGGATTTCCAAC
ATCAATGAGAAGTACAAATTATGTGGTAGCTATCCTCAAGAGCTCATAGTGCCTGCCTGG
ATCACTGACAAAGAACTGGAAAGTGTATCAAGTTTCAGGTCCTGGAAGCGCATCCCTGCC
GTCATCTACAGGCACCAGAGCAATGGAGCTGTCATTGCCCGCTGTGGACAGCCAGAGGTT
AGCTGGTGGGGCTGGCGAAATGCAGATGATGAGCATCTGGTACAGTCAGTAGCCAAAGCT
TGTGCCTCTGACTCCCGATCGAGTGGCAGCAAGCTGTCAACTAGGAACACTTCTCGAGAC
TTTCCCAATGGGGGAGACCTTTCTGACGTGGAGTTCGATTCTTCTCTGTCAAATGCTTCA
GGAGCAGAGAGTTTAGCCATCCAACCGCAGAAGCTTTTGATCTTGGATGCACGCTCCTAT
GCAGCTGCTGTGGCAAACCGAGCCAAAGGAGGAGGCTGCGAATGCCCAGAGTATTACCCA
AACTGTGAAGTTGTGTTTATGGGGATGGCAAACATTCATTCTATTCGGAGGAGTTTTCAG
TCTCTGCGGTTGCTGTGCACTCAGATGCCAGATCCGGGAAATTGGCTATCAGCTCTTGAA
AGCACAAAATGGCTCCATCACTTGTCTGTGCTTCTGAAATCAGCGCTTCTGGTAGTGCAT
GCTGTGGATCAGGATCAGCGGCCGGTGCTAGTACACTGCTCAGATGGCTGGGACCGCACC
CCCCAGATTGTGGCATTGGCTAAGCTCTTGCTGGACCCTTATTACCGAACCATAGAGGGT
TTCCAGGTCCTCGTGGAAATGGAGTGGCTGGATTTTGGCCATAAATTTGCTGACCGGTGT
GGTCATGGGGAGAACTCGGATGATCTGAATGAACGTTGCCCAGTGTTTCTGCAGTGGCTT
GACTGTGTTCATCAGCTTCAGAGGCAATTTCCTTGCTCTTTTGAGTTCAATGAAGCATTC
CTTGTGAAACTGGTGCAGCATACCTATTCCTGCCTGTTTGGAACATTCCTGTGCAACAAC
GCCAAGGAGAGAGGGGAAAAGCATACTCAGGAACGGACATGTTCCGTGTGGTCACTTCTT
CGGGCAGGCAACAAGGCTTTCAAAAACCTACTGTATTCCTCTCAGTCAGAAGCCGTGCTG
TACCCTGTGTGCCATGTGCGTAACCTGATGCTGTGGAGTGCAGTGTACCTGCCCTGCCCA
TCCCCAACCACCCCTGTGGACGACAGCTGTGCACCATACCCAGCCCCAGGCACCAGCCCT
GATGATCCCCCCCTGAGCCGGCTACCAAAGACTAGATCATACGACAATCTGACCACAGCC
TGTGACAACACAGTGCCTCTGGCCAGCCGGCGCTGCAGCGACCCCAGCCTGAACGAGAAG
TGGCAGGAGCACCGGCGCTCACTAGAGCTGAGCAGCCTGGCTGGCCCTGGAGAGGATCCC
CTTTCTGCCGACAGCCTAGGGAAGCCCACCAGAGTGCCGGGGGGTGCCGAGCTTTCTGTT
GCAGCCGGAGTAGCTGAGGGGCAGATGGAGAACATCTTGCAGGAGGCCACCAAAGAGGAG
AGTGGAGTAGAGGAACCTGCCCACAGGGCAGGCATTGAGATACAGGAGGGTAAAGAGGAC
CCTCTCTTAGAAAAGGAGAGCAGGAGGAAGACACCTGAGGCCTCAGCCATTGGACTTCAC
CAAGACCCAGAACTGGGTGATGCTGCTCTGAGGAGCCATCTGGATATGAGCTGGCCTCTG
TTCTCACAGGGCATTTCTGAACAGCAGAGTGGGCTCAGTGTTCTCCTCAGTTCTCTCCAG
GTCCCCCCCAGGGGAGAGGATTCCCTGGAGGTCCCTGTGGAGCAGTTTCGAATAGAAGAG
ATTGCAGAGGGTAGGGAGGAAGCAGTTCTTCCAATCCCAGTAGATGCAAAAGTTGGCTAT
GGTACCTCACAGTCATGTTCTCTGCTACCTTCCCAAGTCCCTTTTGAGACCAGAGGACCA
AACGTGGACAGTTCTACAGACATGTTAGTGGAAGATAAGGTGAAGTCAGTAAGTGGGCCC
CAAGGTCATCATAGATCTTGCCTTGTAAATAGTGGCAAGGACAGGCTTCCTCAGACCATG
GAACCCAGCCCTTCAGAGACAAGCCTGGTCGAGAGGCCCCAAGTGGGGTCTGTGGTGCAT
AGGACTTCCCTTGGCAGCACTCTCAGCCTGACACGTTCCCCTTGTGCCTTGCCTTTAGCC
GAATGTAAAGAGGGGCTTGTGTGCAATGGTGCCCCAGAGACTGAAAACAGGGCCTCAGAG
CAGCCCCCAGGTCTTAGCACCCTCCAGATGTACCCCACACCCAATGGGCATTGCGCCAAT
GGGGAGGCTGGTAGGAGCAAGGACTCACTGAGCCGTCAGCTGTCTGCTATGAGCTGCAGC
TCTGCCCACTTACACTCAAGGAACTTGCACCACAAGTGGCTGCATAGCCACTCAGGAAGG
CCATCTGCAACCAGCAGCCCCGACCAGCCTTCCCGCAGCCACCTGGACGATGATGGCATG
TCAGTGTACACAGACACGATCCAACAGCGCCTGCGTCAGATTGAGTCAGGCCACCAGCAG
GAAGTAGAAACTTTGAAGAAACAAGTCCAGGAGCTGAAGAGTCGCCTGGAGAGCCAGTAC
CTGACCAGCTCCCTACACTTTAATGGAGACTTTGGGGATGAGGTGACTTCAATCCCCGAC
TCGGAAAGCAATCTGGATCAGAACTGTTTGTCTCGCTGCAGCACAGAGATTTTCTCTGAA
GCCAGCTGGGAGCAGGTGGATAAACAGGACACAGAGATGACCCGTTGGCTTCCTGACCAC
CTGGCCGCCCACTGCTATGCGTGCGACAGTGCCTTCTGGCTTGCCAGCAGGAAGCACCAC
TGCAGGAATTGTGGGAACGTATTCTGCTCCAGTTGTTGTAACCAGAAGGTTCCAGTTCCC
AGCCAGCAGCTCTTTGAACCCAGTCGAGTATGCAAGTCTTGCTATAGCAGCCTACATCCC
ACAAGCTCCAGCATTGACCTTGAACTGGATAAGCCCATTGCTGCCACTTCCAACTGA

Protein Properties

Number of Residues

1198

Molecular Weight

133617.635

Theoretical pI

5.8

Pfam Domain Function

FYVE (PF01363 )
Myotub-related (PF06602 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Myotubularin-related protein 3
MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL
HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP
PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN
INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV
SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS
GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ
SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT
PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL
DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL
RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP
DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP
LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED
PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ
VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP
NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH
RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN
GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM
SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD
SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH
CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN

External Links

GenBank ID Protein

10835109

UniProtKB/Swiss-Prot ID

Q13615

UniProtKB/Swiss-Prot Entry Name

MTMR3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_021090.3

GeneCard ID