Showing Protein Large neutral amino acids transporter small subunit 3 (CDBP02185)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP02185
Secondary Accession Numbers Not Available
Name Large neutral amino acids transporter small subunit 3
Description Not Available
Synonyms
  1. L-type amino acid transporter 3
  2. Prostate cancer overexpressed gene 1 protein
  3. Solute carrier family 43 member 1
Gene Name SLC43A1
Protein Type Enzyme
Biological Properties
General Function Involved in transmembrane transport
Specific Function Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer
GO Classification
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11p11.2-p11.1
SNPs SLC43A1
Gene Sequence 
>1680 bp
ATGGCCCCCACGCTGCAACAGGCGTACCGGAGGCGCTGGTGGATGGCCTGCACGGCTGTG
CTGGAGAACCTCTTCTTCTCTGCTGTACTCCTGGGCTGGGGCTCCCTGTTGATCATTCTG
AAGAACGAGGGCTTCTATTCCAGCACGTGCCCAGCTGAGAGCAGCACCAACACCACCCAG
GATGAGCAGCGCAGGTGGCCAGGCTGTGACCAGCAGGACGAGATGCTCAACCTGGGCTTC
ACCATTGGTTCCTTCGTGCTCAGCGCCACCACCCTGCCACTGGGGATCCTCATGGACCGC
TTTGGCCCCCGACCCGTGCGGCTGGTTGGCAGTGCCTGCTTCACTGCGTCCTGCACCCTC
ATGGCCCTGGCCTCCCGGGACGTGGAAGCTCTGTCTCCGTTGATATTCCTGGCGCTGTCC
CTGAATGGCTTTGGTGGCATCTGCCTAACGTTCACTTCACTCACGCTGCCCAACATGTTT
GGGAACCTGCGCTCCACGTTAATGGCCCTCATGATTGGCTCTTACGCCTCTTCTGCCATT
ACGTTCCCAGGAATCAAGCTGATCTACGATGCCGGTGTGGCCTTCGTGGTCATCATGTTC
ACCTGGTCTGGCCTGGCCTGCCTTATCTTTCTGAACTGCACCCTCAACTGGCCCATCGAA
GCCTTTCCTGCCCCTGAGGAAGTCAATTACACGAAGAAGATCAAGCTGAGTGGGCTGGCC
CTGGACCACAAGGTGACAGGTGACCTCTTCTACACCCATGTGACCACCATGGGCCAGAGG
CTCAGCCAGAAGGCCCCCAGCCTGGAGGACGGTTCGGATGCCTTCATGTCACCCCAGGAT
GTTCGGGGCACCTCAGAAAACCTTCCTGAGAGGTCTGTCCCCTTACGCAAGAGCCTCTGC
TCCCCCACTTTCCTGTGGAGCCTCCTCACCATGGGCATGACCCAGCTGCGGATCATCTTC
TACATGGCTGCTGTGAACAAGATGCTGGAGTACCTTGTGACTGGTGGCCAGGAGCATGAG
ACAAATGAACAGCAACAAAAGGTGGCAGAGACAGTTGGGTTCTACTCCTCCGTCTTCGGG
GCCATGCAGCTGTTGTGCCTTCTCACCTGCCCCCTCATTGGCTACATCATGGACTGGCGG
ATCAAGGACTGCGTGGACGCCCCAACTCAGGGCACTGTCCTCGGAGATGCCAGGGACGGG
GTTGCTACCAAATCCATCAGACCACGCTACTGCAAGATCCAAAAGCTCACCAATGCCATC
AGTGCCTTCACCCTGACCAACCTGCTGCTTGTGGGTTTTGGCATCACCTGTCTCATCAAC
AACTTACACCTCCAGTTTGTGACCTTTGTCCTGCACACCATTGTTCGAGGTTTCTTCCAC
TCAGCCTGTGGGAGTCTCTATGCTGCAGTGTTCCCATCCAACCACTTTGGGACGCTGACA
GGCCTGCAGTCCCTCATCAGTGCTGTGTTCGCCTTGCTTCAGCAGCCACTTTTCATGGCG
ATGGTGGGACCCCTGAAAGGAGAGCCCTTCTGGGTGAATCTGGGCCTCCTGCTATTCTCA
CTCCTGGGATTCCTGTTGCCTTCCTACCTCTTCTATTACCGTGCCCGGCTCCAGCAGGAG
TACGCCGCCAATGGGATGGGCCCACTGAAGGTGCTTAGCGGCTCTGAGGTGACCGCATAG
Protein Properties
Number of Residues 559
Molecular Weight 61476.2
Theoretical pI 7.73
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["20-40", "78-98", "105-124", "131-151", "168-188", "191-211", "304-324", "357-377", "419-439", "446-466", "485-505", "510-530"]
Protein Sequence 
>Large neutral amino acids transporter small subunit 3
MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQ
DEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTL
MALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAI
TFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLA
LDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLC
SPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFG
AMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAI
SAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLT
GLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQE
YAANGMGPLKVLSGSEVTA
GenBank ID Protein 38015938
UniProtKB/Swiss-Prot ID O75387
UniProtKB/Swiss-Prot Entry Name LAT3_HUMAN
PDB IDs Not Available
GenBank Gene ID AB103033
GeneCard ID SLC43A1
GenAtlas ID SLC43A1
HGNC ID HGNC:9225
References
General References Not Available