| Identification |
|---|
| HMDB Protein ID
| CDBP02179 |
| Secondary Accession Numbers
| Not Available |
| Name
| Pyrroline-5-carboxylate reductase 3 |
| Description
| Not Available |
| Synonyms
|
- P5C reductase 3
- P5CR 3
- Pyrroline-5-carboxylate reductase-like protein
|
| Gene Name
| PYCRL |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| L-proline biosynthetic process |
| Function |
| catalytic activity |
| pyrroline-5-carboxylate reductase activity |
| oxidoreductase activity, acting on the ch-nh group of donors |
| oxidoreductase activity, acting on the ch-nh group of donors, nad or nadp as acceptor |
| oxidoreductase activity |
| binding |
| Molecular Function |
| pyrroline-5-carboxylate reductase activity |
| nucleotide binding |
| Process |
| metabolic process |
| cellular metabolic process |
| glutamine family amino acid metabolic process |
| proline metabolic process |
| proline biosynthetic process |
| oxidation reduction |
| cellular amino acid and derivative metabolic process |
| cellular amino acid metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | L-proline biosynthesis | Not Available | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| 8q24.3 |
| SNPs
| PYCRL |
| Gene Sequence
|
>825 bp
ATGGCAGCTGCGGAGCCGTCTCCGCGGCGCGTGGGCTTCGTGGGCGCGGGCCGCATGGCG
GGGGCCATCGCGCAGGGCCTCATCAGAGCAGGAAAAGTGGAAGCTCAGCACATACTGGCC
AGTGCACCAACAGACAGGAACCTATGTCACTTTCAAGCTCTGGGTTGCCGGACCACGCAC
TCCAACCAGGAGGTGCTGCAGAGCTGCCTGCTCGTCATCTTTGCCACCAAGCCTCATGTG
CTGCCAGCTGTCCTGGCAGAGGTGGCTCCTGTGGTCACCACTGAACACATCTTGGTGTCC
GTGGCTGCTGGGGTGTCTCTGAGCACCCTGGAGGAGCTGCTGCCCCCGAACACACGGGTG
CTGCGGGTCTTGCCCAACCTGCCCTGTGTGGTCCAGGAAGGGGCCATAGTGATGGCGCGG
GGCCGCCACGTGGGGAGCAGCGAGACCAACCTCCTGCAGCATCTGCTGGAGGCCTGTGGG
CGGTGTGAGGAGGTGCCTGAAGCCTACGTCGACATCCACACTGGCCTCAGTGGCAGTGGC
GTGGCCTTCGTGTGTGCATTCTCCGAGGCCCTGGCTGAAGGAGCCGTCAAGATGGGCATG
CCCAGCAGCCTGGCCCACCGCATCGCTGCCCAGACCCTGCTGGGGACGGCCAAGATGCTG
CTGCACGAGGGCCAACACCCAGCCCAGCTGCGCTCAGACGTGTGCACCCCGGGTGGCACC
ACCATCTATGGACTCCACGCCCTGGAGCAGGGCGGGCTGCGAGCAGCCACCATGAGCGCC
GTGGAGGCTGCCACCTGCCGGGCCAAGGAGCTCAGCAGAAAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 274 |
| Molecular Weight
| 29892.415 |
| Theoretical pI
| 8.109 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Pyrroline-5-carboxylate reductase 3
MAAAEPSPRRVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQALGCRTTH
SNQEVLQSCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLPPNTRV
LRVLPNLPCVVQEGAIVMARGRHVGSSETNLLQHLLEACGRCEEVPEAYVDIHTGLSGSG
VAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGT
TIYGLHALEQGGLRAATMSAVEAATCRAKELSRK
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q53H96 |
| UniProtKB/Swiss-Prot Entry Name
| P5CR3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK001500 |
| GeneCard ID
| PYCRL |
| GenAtlas ID
| PYCRL |
| HGNC ID
| HGNC:25846 |
| References |
|---|
| General References
| Not Available |