Cannabis Compound Database: Showing Protein Beta-1,4-galactosyltransferase 7 (CDBP02172)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP02172

Secondary Accession Numbers

Not Available

Name

Beta-1,4-galactosyltransferase 7

Description

Not Available

Synonyms

Beta-1,4-GalTase 7
Beta4Gal-T7
Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7
UDP-galactose:beta-xylose beta-1,4-galactosyltransferase
XGPT
XGalT-1
Xylosylprotein 4-beta-galactosyltransferase
Xylosylprotein beta-1,4-galactosyltransferase
b4Gal-T7

Gene Name

B4GALT7

Protein Type

Enzyme

Biological Properties

General Function

Involved in transferase activity, transferring glycosyl groups

Specific Function

Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts.

GO Classification

Biological Process
glycosaminoglycan biosynthetic process
extracellular fibril organization
negative regulation of fibroblast proliferation
protein glycosylation
cellular protein modification process
carbohydrate metabolic process
chondroitin sulfate metabolic process
Cellular Component
Golgi cisterna membrane
integral to membrane
Golgi membrane
Function
transferase activity
transferase activity, transferring glycosyl groups
catalytic activity
Molecular Function
metal ion binding
xylosylprotein 4-beta-galactosyltransferase activity
Process
metabolic process
primary metabolic process
carbohydrate metabolic process

Cellular Location

Single-pass type II membrane protein
Golgi apparatus
Golgi stack membrane

Pathways

Name	SMPDB/Pathwhiz	KEGG
protein glycosylation	Not Available	Not Available
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	Not Available
Glycosaminoglycan biosynthesis - heparan sulfate / heparin	Not Available

Gene Properties

Chromosome Location

Locus

5q35.2-q35.3

SNPs

B4GALT7

Gene Sequence

>984 bp
ATGTTCCCCTCGCGGAGGAAAGCGGCGCAGCTGCCCTGGGAGGACGGCAGGTCCGGGTTG
CTCTCCGGCGGCCTCCCTCGGAAGTGTTCCGTCTTCCACCTGTTCGTGGCCTGCCTCTCG
CTGGGCTTCTTCTCCCTACTCTGGCTGCAGCTCAGCTGCTCTGGGGACGTGGCCCGGGCA
GTCAGGGGACAAGGGCAGGAGACCTCGGGCCCTCCCCGCGCCTGCCCCCCAGAGCCGCCC
CCTGAGCACTGGGAAGAAGACGCATCCTGGGGCCCCCACCGCCTGGCAGTGCTGGTGCCC
TTCCGCGAACGCTTCGAGGAGCTCCTGGTCTTCGTGCCCCACATGCGCCGCTTCCTGAGC
AGGAAGAAGATCCGGCACCACATCTACGTGCTCAACCAGGTGGACCACTTCAGGTTCAAC
CGGGCAGCGCTCATCAACGTGGGCTTCCTGGAGAGCAGCAACAGCACGGACTACATTGCC
ATGCACGACGTTGACCTGCTCCCTCTCAACGAGGAGCTGGACTATGGCTTTCCTGAGGCT
GGGCCCTTCCACGTGGCCTCCCCGGAGCTCCACCCTCTCTACCACTACAAGACCTATGTC
GGCGGCATCCTGCTGCTCTCCAAGCAGCACTACCGGCTGTGCAATGGGATGTCCAACCGC
TTCTGGGGCTGGGGCCGCGAGGACGACGAGTTCTACCGGCGCATTAAGGGAGCTGGGCTC
CAGCTTTTCCGCCCCTCGGGAATCACAACTGGGTACAAGACATTTCGCCACCTGCACGAC
CCAGCCTGGCGGAAGAGGGACCAGAAGCGCATCGCAGCTCAAAAACAGGAGCAGTTCAAG
GTGGACAGGGAGGGAGGCCTGAACACTGTGAAGTACCATGTGGCTTCCCGCACTGCCCTG
TCTGTGGGCGGGGCCCCCTGCACTGTCCTCAACATCATGTTGGACTGTGACAAGACCGCC
ACACCCTGGTGCACATTCAGCTGA

Protein Properties

Number of Residues

327

Molecular Weight

37405.53

Theoretical pI

8.982

Pfam Domain Function

Galactosyl_T_2 (PF02709 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Beta-1,4-galactosyltransferase 7
MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARA
VRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLS
RKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEA
GPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGL
QLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTAL
SVGGAPCTVLNIMLDCDKTATPWCTFS

External Links

GenBank ID Protein

5738915

UniProtKB/Swiss-Prot ID

Q9UBV7

UniProtKB/Swiss-Prot Entry Name

B4GT7_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB028600

GeneCard ID