| Identification |
|---|
| HMDB Protein ID
| CDBP02144 |
| Secondary Accession Numbers
| Not Available |
| Name
| ADAMTS-like protein 1 |
| Description
| Not Available |
| Synonyms
|
- ADAMTSL-1
- Punctin-1
|
| Gene Name
| ADAMTSL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metallopeptidase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| proteinaceous extracellular matrix |
| extracellular region part |
| extracellular matrix |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| hydrolase activity |
| transition metal ion binding |
| zinc ion binding |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| metallopeptidase activity |
|
| Cellular Location
|
- Secreted
- extracellular space
- extracellular matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9p21.3 |
| SNPs
| ADAMTSL1 |
| Gene Sequence
|
>5289 bp
ATGGAATGCTGCCGTCGGGCAACTCCTGGCACACTGCTCCTCTTTCTGGCTTTCCTGCTC
CTGAGTTCCAGGACCGCACGCTCCGAGGAGGACCGGGACGGCCTATGGGATGCCTGGGGC
CCATGGAGTGAATGCTCACGCACCTGCGGGGGTGGGGCCTCCTACTCTCTGAGGCGCTGC
CTGAGCAGCAAGAGCTGTGAAGGAAGAAATATCCGATACAGAACATGCAGTAATGTGGAC
TGCCCACCAGAAGCAGGTGATTTCCGAGCTCAGCAATGCTCAGCTCATAATGATGTCAAG
CACCATGGCCAGTTTTATGAATGGCTTCCTGTGTCTAATGACCCTGACAACCCATGTTCA
CTCAAGTGCCAAGCCAAAGGAACAACCCTGGTTGTTGAACTAGCACCTAAGGTCTTAGAT
GGTACGCGTTGCTATACAGAATCTTTGGATATGTGCATCAGTGGTTTATGCCAAATTGTT
GGCTGCGATCACCAGCTGGGAAGCACCGTCAAGGAAGATAACTGTGGGGTCTGCAACGGA
GATGGGTCCACCTGCCGGCTGGTCCGAGGGCAGTATAAATCCCAGCTCTCCGCAACCAAA
TCGGATGATACTGTGGTTGCAATTCCCTATGGAAGTAGACATATTCGCCTTGTCTTAAAA
GGTCCTGATCACTTATATCTGGAAACCAAAACCCTCCAGGGGACTAAAGGTGAAAACAGT
CTCAGCTCCACAGGAACTTTCCTTGTGGACAATTCTAGTGTGGACTTCCAGAAATTTCCA
GACAAAGAGATACTGAGAATGGCTGGACCACTCACAGCAGATTTCATTGTCAAGATTCGT
AACTCGGGCTCCGCTGACAGTACAGTCCAGTTCATCTTCTATCAACCCATCATCCACCGA
TGGAGGGAGACGGATTTCTTTCCTTGCTCAGCAACCTGTGGAGGAGGTTATCAGCTGACA
TCGGCTGAGTGCTACGATCTGAGGAGCAACCGTGTGGTTGCTGACCAATACTGTCACTAT
TACCCAGAGAACATCAAACCCAAACCCAAGCTTCAGGAGTGCAACTTGGATCCTTGTCCA
GCCAGTGACGGATACAAGCAGATCATGCCTTATGACCTCTACCATCCCCTTCCTCGGTGG
GAGGCCACCCCATGGACCGCGTGCTCCTCCTCGTGTGGGGGGGGCATCCAGAGCCGGGCA
GTTTCCTGTGTGGAGGAGGACATCCAGGGGCATGTCACTTCAGTGGAAGAGTGGAAATGC
ATGTACACCCCTAAGATGCCCATCGCGCAGCCCTGCAACATTTTTGACTGCCCTAAATGG
CTGGCACAGGAGTGGTCTCCGTGCACAGTGACATGTGGCCAGGGCCTCAGATACCGTGTG
GTCCTCTGCATCGACCATCGAGGAATGCACACAGGAGGCTGTAGCCCAAAAACAAAGCCC
CACATAAAAGAGGAATGCATCGTACCCACTCCCTGCTATAAACCCAAAGAGAAACTTCCA
GTCGAGGCCAAGTTGCCATGGTTCAAACAAGCTCAAGAGCTAGAAGAAGGAGCTGCTGTG
TCAGAGGAGCCCTCGTTCATCCCAGAGGCCTGGTCGGCCTGCACAGTCACCTGTGGTGTG
GGGACCCAGGTGCGAATAGTCAGGTGCCAGGTGCTCCTGTCTTTCTCTCAGTCCGTGGCT
GACCTGCCTATTGACGAGTGTGAAGGGCCCAAGCCAGCATCCCAGCGTGCCTGTTATGCA
GGCCCATGCAGCGGGGAAATTCCTGAGTTCAACCCAGACGAGACAGATGGGCTCTTTGGT
GGCCTGCAGGATTTCGACGAGCTGTATGACTGGGAGTATGAGGGGTTCACCAAGTGCTCC
GAGTCCTGTGGAGGAGGTGTCCAGGAGGCTGTGGTGAGCTGCTTGAACAAACAGACTCGG
GAGCCTGCTGAGGAGAACCTGTGCGTGACCAGCCGCCGGCCCCCACAGCTCCTGAAGTCC
TGCAATTTGGATCCCTGCCCAGCAAGGTGGGAAATTGGCAAGTGGAGTCCATGTAGTCTC
ACATGTGGGGTCGGCCTACAGACCAGAGACGTCTTCTGCAGCCACCTGCTTTCCAGAGAG
ATGAATGAAACAGTCATCCTGGCTGATGAGCTGTGTCGCCAGCCCAAGCCCAGCACGGTG
CAAGCTTGTAACCGCTTTAATTGCCCCCCAGCCTGGTACCCTGCACAGTGGCAGCCGTGT
TCCAGAACGTGTGGCGGGGGTGTTCAGAAACGTGAGGTTCTTTGCAAGCAGCGCATGGCT
GATGGCAGCTTCCTGGAGCTTCCTGAGACCTTCTGTTCAGCTTCAAAACCTGCCTGCCAG
CAAGCATGCAAGAAAGATGACTGTCCCAGCGAGTGGCTTCTCTCAGACTGGACAGAGTGT
TCCACAAGCTGCGGGGAAGGCACCCAGACTCGAAGCGCCATTTGCCGAAAGATGCTGAAA
ACCGGCCTCTCAACGGTTGTCAATTCCACCCTGTGCCCGCCCCTGCCTTTCTCTTCCTCC
ATCAGGCCCTGTATGCTGGCAACCTGTGCAAGGCCCGGGCGGCCATCCACGAAGCACAGC
CCGCACATCGCGGCCGCCAGGAAGGTCTACATACAGACTCGCAGGCAGAGGAAGCTGCAC
TTCGTGGTGGGGGGCTTCGCCTACCTGCTCCCCAAGACGGCGGTGGTGCTGCGCTGCCCG
GCGCGCAGGGTCCGCAAGCCCCTCATCACCTGGGAGAAGGACGGCCAGCACCTCATCAGC
TCGACGCACGTCACGGTGGCCCCCTTCGGCTATCTCAAGATCCACCGCCTCAAGCCCTCG
GATGCAGGCGTCTACACCTGCTCAGCGGGCCCGGCCCGGGAGCACTTTGTGATTAAGCTC
ATCGGAGGCAACCGCAAGCTCGTGGCCCGGCCCTTGAGCCCGAGAAGTGAGGAAGAGGTG
CTTGCGGGGAGGAAGGGCGGCCCGAAGGAGGCCCTGCAGACCCACAAACACCAGAACGGG
ATCTTCTCCAACGGCAGCAAGGCGGAGAAGCGGGGCCTGGCCGCCAACCCGGGGAGCCGC
TACGACGACCTCGTCTCCCGGCTGCTGGAGCAGGGCGGCTGGCCCGGAGAGCTGCTGGCC
TCGTGGGAGGCGCAGGACTCTGCGGAAAGGAACACGACCTCGGAGGAGGACCCGGGTGCA
GAGCAAGTGCTCCTGCACCTGCCCTTCACCATGGTGACCGAGCAGCGGCGCCTGGACGAC
ATCCTGGGGAACCTCTCCCAGCAGCCCGAGGAGCTGCGCGACCTCTACAGCAAGCACCTG
GTGGCCCAGCTGGCCCAGGAGATCTTCCGCAGCCACCTGGAGCACCAGGACACGCTCCTG
AAGCCCTCGGAGCGCAGGACTTCCCCAGTGACTCTCTCGCCTCATAAACACGTGTCTGGC
TTCAGCAGCTCCCTGCGGACCTCCTCCACCGGGGACGCCGGGGGAGGCTCTCGAAGGCCA
CACCGCAAGCCCACCATCCTGCGCAAGATCTCAGCGGCCCAGCAGCTCTCAGCCTCGGAG
GTGGTCACCCACCTGGGGCAGACGGTGGCCCTGGCCAGCGGGACACTGAGTGTTCTTCTG
CACTGTGAGGCCATCGGCCACCCAAGGCCTACCATCAGCTGGGCCAGGAATGGAGAAGAA
GTTCAGTTCAGTGACAGGATTCTTCTACAGCCAGATGATTCCTTACAGATCTTGGCACCA
GTGGAAGCAGATGTGGGTTTCTACACTTGCAATGCCACCAATGCCTTGGGATACGACTCT
GTCTCCATTGCCGTCACATTAGCAGGAAAGCCACTAGTGAAAACGTCACGAATGACAGTG
ATCAACACGGAGAAGCCTGCAGTCACAGTCGATATAGGAAGCACCATCAAAACAGTGCAG
GGAGTGAATGTGACAATCAACTGCCAGGTTGCAGGAGTGCCTGAAGCTGAAGTCACTTGG
TTCAGGAATAAAAGCAAACTGGGCTCCCCGCACCATCTGCACGAAGGCTCCTTGCTGCTC
ACAAACGTGTCCTCCTCGGATCAGGGCCTGTACTCCTGCAGGGCGGCCAATCTTCATGGA
GAGCTGACTGAGAGCACCCAGCTGCTGATCCTAGATCCCCCCCAAGTCCCCACACAGTTG
GAAGACATCAGGGCCTTGCTCGCTGCCACTGGACCGAACCTTCCTTCAGTGCTGACGTCT
CCTCTGGGAACACAGCTGGTCCTGGATCCTGGGAATTCTGCTCTCCTTGGCTGCCCCATC
AAAGGTCACCCTGTCCCTAATATCACCTGGTTTCATGGTGGTCAGCCAATTGTCACTGCC
ACAGGACTGACGCATCACATCTTGGCAGCTGGACAGATCCTTCAAGTTGCAAACCTTAGC
GGTGGGTCTCAAGGGGAATTCAGCTGCCTTGCTCAGAATGAGGCAGGGGTGCTCATGCAG
AAGGCATCTTTAGTGATCCAAGATTACTGGTGGTCTGTGGACAGACTGGCAACCTGCTCA
GCCTCCTGTGGTAACCGGGGGGTTCAGCAGCCCCGCTTGAGGTGCCTGCTGAACAGCACG
GAGGTCAACCCTGCCCACTGCGCAGGGAAGGTTCGCCCTGCGGTGCAGCCCATCGCGTGC
AACCGGAGAGACTGCCCTTCTCGGTGGATGGTGACCTCCTGGTCTGCCTGTACCCGGAGC
TGTGGGGGAGGTGTCCAGACCCGCAGGGTGACCTGTCAAAAGCTGAAAGCCTCTGGGATC
TCCACCCCTGTGTCCAATGACATGTGCACCCAGGTCGCCAAGCGGCCTGTGGACACCCAG
GCCTGTAACCAGCAGCTGTGTGTGGAGTGGGCCTTCTCCAGCTGGGGCCAGTGCAATGGG
CCTTGCATCGGGCCTCACCTAGCTGTGCAACACAGACAAGTCTTCTGCCAGACACGGGAT
GGCATCACCTTACCATCAGAGCAGTGCAGTGCTCTTCCGAGGCCTGTGAGCACCCAGAAC
TGCTGGTCAGAGGCCTGCAGTGTACACTGGAGAGTCAGCCTGTGGACCCTGTGCACAGCT
ACCTGTGGCAACTACGGCTTCCAGTCCCGGCGTGTGGAGTGTGTGCATGCCCGCACCAAC
AAGGCAGTGCCTGAGCACCTGTGCTCCTGGGGGCCCCGGCCTGCCAACTGGCAGCGCTGC
AACATCACCCCATGTGAAAACATGGAGTGCAGAGACACCACCAGGTACTGCGAGAAGGTG
AAACAGCTGAAACTCTGCCAACTCAGCCAGTTTAAATCTCGCTGCTGTGGAACTTGTGGC
AAAGCGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1762 |
| Molecular Weight
| 193407.5 |
| Theoretical pI
| 7.81 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>ADAMTS-like protein 1
MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRC
LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCS
LKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNG
DGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTKGENS
LSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPIIHR
WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP
ASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKC
MYTPKMPIAQPCNIFDCPKWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSPKTKP
HIKEECIVPTPCYKPKEKLPVEAKLPWFKQAQELEEGAAVSEEPSFIPEAWSACTVTCGV
GTQVRIVRCQVLLSFSQSVADLPIDECEGPKPASQRACYAGPCSGEIPEFNPDETDGLFG
GLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKS
CNLDPCPARWEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETVILADELCRQPKPSTV
QACNRFNCPPAWYPAQWQPCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQ
QACKKDDCPSEWLLSDWTECSTSCGEGTQTRSAICRKMLKTGLSTVVNSTLCPPLPFSSS
IRPCMLATCARPGRPSTKHSPHIAAARKVYIQTRRQRKLHFVVGGFAYLLPKTAVVLRCP
ARRVRKPLITWEKDGQHLISSTHVTVAPFGYLKIHRLKPSDAGVYTCSAGPAREHFVIKL
IGGNRKLVARPLSPRSEEEVLAGRKGGPKEALQTHKHQNGIFSNGSKAEKRGLAANPGSR
YDDLVSRLLEQGGWPGELLASWEAQDSAERNTTSEEDPGAEQVLLHLPFTMVTEQRRLDD
ILGNLSQQPEELRDLYSKHLVAQLAQEIFRSHLEHQDTLLKPSERRTSPVTLSPHKHVSG
FSSSLRTSSTGDAGGGSRRPHRKPTILRKISAAQQLSASEVVTHLGQTVALASGTLSVLL
HCEAIGHPRPTISWARNGEEVQFSDRILLQPDDSLQILAPVEADVGFYTCNATNALGYDS
VSIAVTLAGKPLVKTSRMTVINTEKPAVTVDIGSTIKTVQGVNVTINCQVAGVPEAEVTW
FRNKSKLGSPHHLHEGSLLLTNVSSSDQGLYSCRAANLHGELTESTQLLILDPPQVPTQL
EDIRALLAATGPNLPSVLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTA
TGLTHHILAAGQILQVANLSGGSQGEFSCLAQNEAGVLMQKASLVIQDYWWSVDRLATCS
ASCGNRGVQQPRLRCLLNSTEVNPAHCAGKVRPAVQPIACNRRDCPSRWMVTSWSACTRS
CGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLCVEWAFSSWGQCNG
PCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQNCWSEACSVHWRVSLWTLCTA
TCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPCENMECRDTTRYCEKV
KQLKLCQLSQFKSRCCGTCGKA
|
| External Links |
|---|
| GenBank ID Protein
| 154275767 |
| UniProtKB/Swiss-Prot ID
| Q8N6G6 |
| UniProtKB/Swiss-Prot Entry Name
| ATL1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001040272.4 |
| GeneCard ID
| ADAMTSL1 |
| GenAtlas ID
| ADAMTSL1 |
| HGNC ID
| HGNC:14632 |
| References |
|---|
| General References
| Not Available |