| Identification |
| HMDB Protein ID
| CDBP02123 |
| Secondary Accession Numbers
| Not Available |
| Name
| Myosin regulatory light chain 12A |
| Description
| Not Available |
| Synonyms
|
- MLC-2B
- Myosin RLC
- Myosin regulatory light chain 2, nonsarcomeric
- Myosin regulatory light chain MRLC3
|
| Gene Name
| MYL12A |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in calcium ion binding |
| Specific Function
| Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 18p11.31 |
| SNPs
| MYL12A |
| Gene Sequence
|
>516 bp
ATGTCGAGCAAAAGAACAAAGACCAAGACCAAGAAGCGCCCTCAGCGTGCAACATCCAAT
GTGTTTGCTATGTTTGACCAGTCACAGATTCAGGAGTTCAAAGAGGCCTTCAACATGATT
GATCAGAACAGAGATGGTTTCATCGACAAGGAAGATTTGCATGATATGCTTGCTTCATTG
GGGAAGAATCCAACTGATGAGTATCTAGATGCCATGATGAATGAGGCTCCAGGCCCCATC
AATTTCACCATGTTCCTCACCATGTTTGGTGAGAAGTTAAATGGCACAGATCCTGAAGAT
GTCATCAGAAATGCCTTTGCTTGCTTTGATGAAGAAGCAACTGGCACCATACAGGAAGAT
TACTTGAGAGAGCTGCTGACAACCATGGGGGATCGGTTTACAGATGAGGAAGTGGATGAG
CTGTACAGAGAAGCACCTATTGATAAAAAGGGGAATTTCAATTACATCGAGTTCACACGC
ATCCTGAAACATGGAGCCAAAGACAAAGATGACTGA
|
| Protein Properties |
| Number of Residues
| 171 |
| Molecular Weight
| 19794.0 |
| Theoretical pI
| 4.4 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Myosin regulatory light chain 12A
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL
GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED
YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
|
| External Links |
| GenBank ID Protein
| 16741043 |
| UniProtKB/Swiss-Prot ID
| P19105 |
| UniProtKB/Swiss-Prot Entry Name
| ML12A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC016372 |
| GeneCard ID
| MYL12A |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
| General References
| Not Available |