Showing Protein Pulmonary surfactant-associated protein A2 (CDBP02045)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02045
Secondary Accession Numbers Not Available
Name Pulmonary surfactant-associated protein A2
Description Not Available
Synonyms
  1. 35 kDa pulmonary surfactant-associated protein
  2. Alveolar proteinosis protein
  3. Collectin-5
  4. PSP-A
  5. PSPA
  6. SP-A
  7. SP-A2
Gene Name SFTPA2
Protein Type Enzyme
Biological Properties
General Function Involved in sugar binding
Specific Function In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration
GO Classification
Function
binding
Cellular Location
  1. Secreted
  2. Secreted
  3. extracellular space
  4. extracellular space
  5. extracellular matrix
  6. surface film
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q22.3
SNPs SFTPA2
Gene Sequence 
>747 bp
ATGTGGCTGTGCCCTCTGGCCCTCAACCTCATCTTGATGGCAGCCTCTGGTGCTGCGTGC
GAAGTGAAGGACGTTTGTGTTGGAAGCCCTGGTATCCCCGGCACTCCTGGATCCCACGGC
CTGCCAGGCAGGGACGGGAGAGATGGTGTCAAAGGAGACCCTGGCCCTCCAGGCCCCATG
GGTCCGCCTGGAGAAACACCATGTCCTCCTGGGAATAATGGGCTGCCTGGAGCCCCTGGT
GTCCCTGGAGAGCGTGGAGAGAAGGGGGAGGCTGGCGAGAGAGGCCCTCCAGGGCTTCCA
GCTCATCTAGATGAGGAGCTCCAAGCCACACTCCACGACTTCAGACATCAAATCCTGCAG
ACAAGGGGAGCCCTCAGTCTGCAGGGCTCCATAATGACAGTAGGAGAGAAGGTCTTCTCC
AGCAATGGGCAGTCCATCACTTTTGATGCCATTCAGGAGGCATGTGCCAGAGCAGGCGGC
CGCATTGCTGTCCCAAGGAATCCAGAGGAAAATGAGGCCATTGCAAGCTTCGTGAAGAAG
TACAACACATATGCCTATGTAGGCCTGACTGAGGGTCCCAGCCCTGGAGACTTCCGCTAC
TCAGATGGGACCCCTGTAAACTACACCAACTGGTACCGAGGGGAGCCTGCAGGTCGGGGA
AAAGAGCAGTGTGTGGAGATGTACACAGATGGGCAGTGGAATGACAGGAACTGCCTGTAC
TCCCGACTGACCATCTGTGAGTTCTGA
Protein Properties
Number of Residues 248
Molecular Weight 26182.1
Theoretical pI 4.82
Pfam Domain Function
Signals
  • ["1-20"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Pulmonary surfactant-associated protein A2
MWLCPLALNLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPM
GPPGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLPAHLDEELQATLHDFRHQILQ
TRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKK
YNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLY
SRLTICEF
GenBank ID Protein 27501930
UniProtKB/Swiss-Prot ID Q8IWL1
UniProtKB/Swiss-Prot Entry Name SFPA2_HUMAN
PDB IDs Not Available
GenBank Gene ID AY206682
GeneCard ID SFTPA2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available