Showing Protein Anthrax toxin receptor 1 (CDBP02038)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02038
Secondary Accession Numbers Not Available
Name Anthrax toxin receptor 1
Description Not Available
Synonyms
  1. Tumor endothelial marker 8
Gene Name ANTXR1
Protein Type Receptor
Biological Properties
General Function Involved in receptor activity
Specific Function Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
receptor activity
molecular transducer activity
signal transducer activity
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
  3. Single-pass type I membrane protein
  4. Cell projection
  5. Cell projection
  6. lamellipodium membrane
  7. filopodium membrane
  8. Single- pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p13.1
SNPs ANTXR1
Gene Sequence 
>1695 bp
ATGGCCACGGCGGAGCGGAGAGCCCTCGGCATCGGCTTCCAGTGGCTCTCTTTGGCCACT
CTGGTGCTCATCTGCGCCGGGCAAGGGGGACGCAGGGAGGATGGGGGTCCAGCCTGCTAC
GGCGGATTTGACCTGTACTTCATTTTGGACAAATCAGGAAGTGTGCTGCACCACTGGAAT
GAAATCTATTACTTTGTGGAACAGTTGGCTCACAAATTCATCAGCCCACAGTTGAGAATG
TCCTTTATTGTTTTCTCCACCCGAGGAACAACCTTAATGAAACTGACAGAAGACAGAGAA
CAAATCCGTCAAGGCCTAGAAGAACTCCAGAAAGTTCTGCCAGGAGGAGACACTTACATG
CATGAAGGATTTGAAAGGGCCAGTGAGCAGATTTATTATGAAAACAGACAAGGGTACAGG
ACAGCCAGCGTCATCATTGCTTTGACTGATGGAGAACTCCATGAAGATCTCTTTTTCTAT
TCAGAGAGGGAGGCTAATAGGTCTCGAGATCTTGGTGCAATTGTTTACTGTGTTGGTGTG
AAAGATTTCAATGAGACACAGCTGGCCCGGATTGCGGACAGTAAGGATCATGTGTTTCCC
GTGAATGACGGCTTTCAGGCTCTGCAAGGCATCATCCACTCAATTTTGAAGAAGTCCTGC
ATCGAAATTCTAGCAGCTGAACCATCCACCATATGTGCAGGAGAGTCATTTCAAGTTGTC
GTGAGAGGAAACGGCTTCCGACATGCCCGCAACGTGGACAGGGTCCTCTGCAGCTTCAAG
ATCAATGACTCGGTCACACTCAATGAGAAGCCCTTTTCTGTGGAAGATACTTATTTACTG
TGTCCAGCGCCTATCTTAAAAGAAGTTGGCATGAAAGCTGCACTCCAGGTCAGCATGAAC
GATGGCCTCTCTTTTATCTCCAGTTCTGTCATCATCACCACCACACACTGTTCTGACGGT
TCCATCCTGGCCATCGCCCTGCTGATCCTGTTCCTGCTCCTAGCCCTGGCTCTCCTCTGG
TGGTTCTGGCCCCTCTGCTGCACTGTGATTATCAAGGAGGTCCCTCCACCCCCTGCCGAG
GAGAGTGAGGAAGAAGATGATGATGGTCTGCCTAAGAAAAAGTGGCCAACGGTAGACGCC
TCTTATTATGGTGGGAGAGGCGTTGGAGGCATTAAAAGAATGGAGGTTCGTTGGGGAGAA
AAGGGCTCCACAGAAGAAGGTGCTAAGTTGGAAAAGGCAAAGAATGCAAGAGTCAAGATG
CCGGAGCAGGAATATGAATTCCCTGAGCCGCGAAATCTCAACAACAATATGCGTCGGCCT
TCTTCCCCCCGGAAGTGGTACTCTCCAATCAAGGGAAAACTCGATGCCTTGTGGGTCCTA
CTGAGGAAAGGATATGATCGTGTGTCTGTGATGCGTCCACAGCCAGGAGACACGGGGCGC
TGCATCAACTTCACCAGGGTCAAGAACAACCAGCCAGCCAAGTACCCACTCAACAACGCC
TACCACACCTCCTCGCCGCCTCCTGCCCCCATCTACACTCCCCCACCTCCTGCGCCCCAC
TGCCCTCCCCCGCCCCCCAGCGCCCCTACCCCTCCCATCCCGTCCCCACCTTCCACCCTT
CCCCCTCCTCCCCAGGCTCCACCTCCCAACAGGGCACCTCCTCCCTCCCGCCCTCCTCCA
AGGCCTTCTGTCTAG
Protein Properties
Number of Residues 564
Molecular Weight 62788.4
Theoretical pI 7.66
Pfam Domain Function
Signals
  • ["1-32"]
Transmembrane Regions
  • ["322-342"]
Protein Sequence 
>Anthrax toxin receptor 1
MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN
EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM
HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV
KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV
VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN
DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE
ESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKM
PEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGR
CINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL
PPPPQAPPPNRAPPPSRPPPRPSV
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9H6X2
UniProtKB/Swiss-Prot Entry Name ANTR1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF279145
GeneCard ID ANTXR1
GenAtlas ID ANTXR1
HGNC ID HGNC:21014
References
General References Not Available