| Identification |
|---|
| HMDB Protein ID
| CDBP02029 |
| Secondary Accession Numbers
| Not Available |
| Name
| Brevican core protein |
| Description
| Not Available |
| Synonyms
|
- BEHAB
- Brain-enriched hyaluronan-binding protein
- Chondroitin sulfate proteoglycan 7
|
| Gene Name
| BCAN |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sugar binding |
| Specific Function
| May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans |
| GO Classification
|
| Function |
| binding |
| pattern binding |
| polysaccharide binding |
| glycosaminoglycan binding |
| hyaluronic acid binding |
| carbohydrate binding |
| sugar binding |
| Process |
| cell adhesion |
| cellular process |
|
| Cellular Location
|
- Lipid-anchor
- GPI- anchor
- Isoform 2:Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q31 |
| SNPs
| BCAN |
| Gene Sequence
|
>2736 bp
ATGGCCCAGCTGTTCCTGCCCCTGCTGGCAGCCCTGGTCCTGGCCCAGGCTCCTGCAGCT
TTAGCAGATGTTCTGGAAGGAGACAGCTCAGAGGACCGCGCTTTTCGCGTGCGCATCGCG
GGCGACGCGCCACTGCAGGGCGTGCTCGGCGGCGCCCTCACCATCCCTTGCCACGTCCAC
TACCTGCGGCCACCGCCGAGCCGCCGGGCTGTGCTGGGCTCTCCGCGGGTCAAGTGGACT
TTCCTGTCCCGGGGCCGGGAGGCAGAGGTGCTGGTGGCGCGGGGAGTGCGCGTCAAGGTG
AACGAGGCCTACCGGTTCCGCGTGGCACTGCCTGCGTACCCAGCGTCGCTCACCGACGTC
TCCCTGGCGCTGAGCGAGCTGCGCCCCAACGACTCAGGTATCTATCGCTGTGAGGTCCAG
CACGGCATCGATGACAGCAGCGACGCTGTGGAGGTCAAGGTCAAAGGGGTCGTCTTTCTC
TACCGAGAGGGCTCTGCCCGCTATGCTTTCTCCTTTTCTGGGGCCCAGGAGGCCTGTGCC
CGCATTGGAGCCCACATCGCCACCCCGGAGCAGCTCTATGCCGCCTACCTTGGGGGCTAT
GAGCAATGTGATGCTGGCTGGCTGTCGGATCAGACCGTGAGGTATCCCATCCAGACCCCA
CGAGAGGCCTGTTACGGAGACATGGATGGCTTCCCCGGGGTCCGGAACTATGGTGTGGTG
GACCCGGATGACCTCTATGATGTGTACTGTTATGCTGAAGACCTAAATGGAGAATTGTTC
CTGGGTGACCCTCCAGAGAAGCTGACATTGGAGGAAGCACGGGCGTACTGCCAGGAGCGG
GGTGCAGAGATTGCCACCACGGGCCAACTGTATGCAGCCTGGGATGGTGGCCTGGACCAC
TGCAGCCCAGGGTGGCTAGCTGATGGCAGTGTGCGCTACCCCATCGTCACACCCAGCCAG
CGCTGTGGTGGGGGCTTGCCTGGTGTCAAGACTCTCTTCCTCTTCCCCAACCAGACTGGC
TTCCCCAATAAGCACAGCCGCTTCAACGTCTACTGCTTCCGAGACTCGGCCCAGCCTTCT
GCCATCCCTGAGGCCTCCAACCCAGCCTCCAACCCAGCCTCTGATGGACTAGAGGCTATC
GTCACAGTGACAGAGACCCTGGAGGAACTGCAGCTGCCTCAGGAAGCCACAGAGAGTGAA
TCCCGTGGGGCCATCTACTCCATCCCCATCATGGAGGACGGAGGAGGTGGAAGCTCCACT
CCAGAAGACCCAGCAGAGGCCCCTAGGACGCTCCTAGAATTTGAAACACAATCCATGGTA
CCGCCCACGGGGTTCTCAGAAGAGGAAGGTAAGGCATTGGAGGAAGAAGAGAAATATGAA
GATGAAGAAGAGAAAGAGGAGGAAGAAGAAGAGGAGGAGGTGGAGGATGAGGCTCTGTGG
GCATGGCCCAGCGAGCTCAGCAGCCCGGGCCCTGAGGCCTCTCTCCCCACTGAGCCAGCA
GCCCAGGAGGAGTCACTCTCCCAGGCGCCAGCAAGGGCAGTCCTGCAGCCTGGTGCATCA
CCACTTCCTGATGGAGAGTCAGAAGCTTCCAGGCCTCCAAGGGTCCATGGACCACCTACT
GAGACTCTGCCCACTCCCAGGGAGAGGAACCTAGCATCCCCATCACCTTCCACTCTGGTT
GAGGCAAGAGAGGTGGGGGAGGCAACTGGTGGTCCTGAGCTATCTGGGGTCCCTCGAGGA
GAGAGCGAGGAGACAGGAAGCTCCGAGGGTGCCCCTTCCCTGCTTCCAGCCACACGGGCC
CCTGAGGGTACCAGGGAGCTGGAGGCCCCCTCTGAAGATAATTCTGGAAGAACTGCCCCA
GCAGGGACCTCAGTGCAGGCCCAGCCAGTGCTGCCCACTGACAGCGCCAGCCGAGGTGGA
GTGGCCGTGGTCCCCGCATCAGGTGACTGTGTCCCCAGCCCCTGCCACAATGGTGGGACA
TGCTTGGAGGAGGAGGAAGGGGTCCGCTGCCTATGTCTGCCTGGCTATGGGGGGGACCTG
TGCGATGTTGGCCTCCGCTTCTGCAACCCCGGCTGGGACGCCTTCCAGGGCGCCTGCTAC
AAGCACTTTTCCACACGAAGGAGCTGGGAGGAGGCAGAGACCCAGTGCCGGATGTACGGC
GCGCATCTGGCCAGCATCAGCACACCCGAGGAACAGGACTTCATCAACAACCGGTACCGG
GAGTACCAGTGGATCGGACTCAACGACAGGACCATCGAAGGCGACTTCTTGTGGTCGGAT
GGCGTCCCCCTGCTCTATGAGAACTGGAACCCTGGGCAGCCTGACAGCTACTTCCTGTCT
GGAGAGAACTGCGTGGTCATGGTGTGGCATGATCAGGGACAATGGAGTGACGTGCCCTGC
AACTACCACCTGTCCTACACCTGCAAGATGGGGCTGGTGTCCTGTGGGCCGCCACCGGAG
CTGCCCCTGGCTCAAGTGTTCGGCCGCCCACGGCTGCGCTATGAGGTGGACACTGTGCTT
CGCTACCGGTGCCGGGAAGGACTGGCCCAGCGCAATCTGCCGCTGATCCGATGCCAAGAG
AACGGTCGTTGGGAGGCCCCCCAGATCTCCTGTGTGCCCAGAAGACCTGCCCGAGCTCTG
CACCCAGAGGAGGACCCAGAAGGACGTCAGGGGAGGCTACTGGGACGCTGGAAGGCGCTG
TTGATCCCCCCTTCCAGCCCCATGCCAGGTCCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 911 |
| Molecular Weight
| 99117.1 |
| Theoretical pI
| 4.28 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Brevican core protein
MAQLFLPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVH
YLRPPPSRRAVLGSPRVKWTFLSRGREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDV
SLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACA
RIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVV
DPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDH
CSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPS
AIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSST
PEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALW
AWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT
ETLPTPRERNLASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRA
PEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPCHNGGT
CLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYG
AHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLS
GENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVL
RYRCREGLAQRNLPLIRCQENGRWEAPQISCVPRRPARALHPEEDPEGRQGRLLGRWKAL
LIPPSSPMPGP
|
| External Links |
|---|
| GenBank ID Protein
| 10798901 |
| UniProtKB/Swiss-Prot ID
| Q96GW7 |
| UniProtKB/Swiss-Prot Entry Name
| PGCB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF228710 |
| GeneCard ID
| BCAN |
| GenAtlas ID
| BCAN |
| HGNC ID
| HGNC:23059 |
| References |
|---|
| General References
| Not Available |