Showing Protein Midkine (CDBP01993)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP01993
Secondary Accession Numbers Not Available
Name Midkine
Description Not Available
Synonyms
  1. ARAP
  2. Amphiregulin-associated protein
  3. MK
  4. Midgestation and kidney protein
  5. Neurite outgrowth-promoting factor 2
  6. Neurite outgrowth-promoting protein
Gene Name MDK
Protein Type Enzyme
Biological Properties
General Function Involved in growth factor activity
Specific Function Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11p11.2
SNPs MDK
Gene Sequence 
>432 bp
ATGCAGCACCGAGGCTTCCTCCTCCTCACCCTCCTCGCCCTGCTGGCGCTCACCTCCGCG
GTCGCCAAAAAGAAAGATAAGGTGAAGAAGGGCGGCCCGGGGAGCGAGTGCGCTGAGTGG
GCCTGGGGGCCCTGCACCCCCAGCAGCAAGGATTGCGGCGTGGGTTTCCGCGAGGGCACC
TGCGGGGCCCAGACCCAGCGCATCCGGTGCAGGGTGCCCTGCAACTGGAAGAAGGAGTTT
GGAGCCGACTGCAAGTACAAGTTTGAGAACTGGGGTGCGTGTGATGGGGGCACAGGCACC
AAAGTCCGCCAAGGCACCCTGAAGAAGGCGCGCTACAATGCTCAGTGCCAGGAGACCATC
CGCGTCACCAAGCCCTGCACCCCCAAGACCAAAGCAAAGGCCAAAGCCAAGAAAGGGAAG
GGAAAGGACTAG
Protein Properties
Number of Residues 143
Molecular Weight 15585.1
Theoretical pI 10.49
Pfam Domain Function
Signals
  • ["1-20"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Midkine
MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGT
CGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETI
RVTKPCTPKTKAKAKAKKGKGKD
GenBank ID Protein 15079798
UniProtKB/Swiss-Prot ID P21741
UniProtKB/Swiss-Prot Entry Name MK_HUMAN
PDB IDs
GenBank Gene ID BC011704
GeneCard ID MDK
GenAtlas ID MDK
HGNC ID HGNC:6972
References
General References Not Available